#OTU ID	AB	AB	AB	AB	AB	AB	AB	AB	AB	AB	AB	AB	AB	AB	AB	AB	AB	AB	AB	AB	AB	AB	AB	AB	AB	AB	AB	KO	KO	KO	KO	KO	AB	AB	AB	AB	AB	KO	KO	KO	KO	KO	KO	KO	KO	KO	KO	KO	KO	KO	KO	AB	AB	AB	AB	AB	KO	KO	KO	KO	KO	KO	KO	KO	KO	KO
Cellular Processes|Cell Communication|Adherens junction	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Cellular Processes|Cell Communication|Focal adhesion	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Cellular Processes|Cell Communication|Tight junction	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Cellular Processes|Cell Growth and Death|Apoptosis	49.0	5.0	6.0	4.0	46.0	1000.0	87.0	32.0	58.0	75.0	222.0	71.0	13.0	153.0	191.0	110.0	68.0	77.0	37.0	18.0	2.0	16.0	5.0	16.0	59.0	16.0	111.0	2.0	33.0	13.0	9.0	87.0	675.0	117.0	72.0	57.0	110.0	2445.0	739.0	249.0	231.0	173.0	244.0	106.0	116.0	114.0	538.0	1051.0	408.0	1024.0	505.0	917.0	20.0	37.0	315.0	444.0	843.0	513.0	797.0	984.0	467.0	776.0	73.0	324.0	30.0	611.0
Cellular Processes|Cell Growth and Death|Cell cycle	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Cellular Processes|Cell Growth and Death|Cell cycle - Caulobacter	74347.0	84094.0	68466.0	60937.0	47713.0	68709.0	78798.0	87826.0	76565.0	66206.0	64395.0	70365.0	71853.0	84024.0	64054.0	54591.0	69895.0	77928.0	47567.0	61495.0	77057.0	72243.0	102448.0	72382.0	72983.0	117569.0	81465.0	54360.0	66314.0	87394.0	65591.0	63366.0	116169.0	99270.0	93272.0	96555.0	68597.0	119036.0	93470.0	75794.0	128898.0	54323.0	89731.0	66232.0	70620.0	109156.0	66806.0	58655.0	47683.0	59240.0	43405.0	68771.0	65247.0	52513.0	62321.0	96690.0	63833.0	36661.0	59398.0	60669.0	67446.0	70045.0	66235.0	118418.0	96762.0	94283.0
Cellular Processes|Cell Growth and Death|Cell cycle - yeast	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Cellular Processes|Cell Growth and Death|Meiosis - yeast	617.0	948.0	1051.0	1162.0	101.0	3220.0	4434.0	4748.0	4211.0	4649.0	2046.0	1799.0	1845.0	2067.0	1528.0	670.0	406.0	403.0	345.0	283.0	3.0	84.0	1426.0	4517.0	5420.0	2918.0	2530.0	697.0	970.0	1743.0	1585.0	2445.0	2897.0	2199.0	752.0	1609.0	1350.0	1110.0	958.0	1592.0	2816.0	1282.0	4120.0	2610.0	2572.0	3198.0	4335.0	3137.0	2474.0	3115.0	2198.0	613.0	1925.0	1601.0	854.0	1039.0	1539.0	1013.0	1324.0	1181.0	1691.0	241.0	106.0	3882.0	3983.0	3775.0
Cellular Processes|Cell Growth and Death|Oocyte meiosis	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Cellular Processes|Cell Growth and Death|p53 signaling pathway	0.0	0.0	0.0	0.0	0.0	10.0	4.0	1.0	2.0	0.0	0.0	0.0	0.0	2.0	6.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	2.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2400.0	737.0	0.0	2.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.0	0.0	2.0	0.0	1.0	0.0	1.0	0.0
Cellular Processes|Cell Motility|Bacterial chemotaxis	30492.0	32969.0	23668.0	20875.0	39394.0	33392.0	52037.0	55928.0	47684.0	41120.0	25665.0	30665.0	29138.0	36848.0	25067.0	20053.0	19190.0	19366.0	17793.0	22199.0	42024.0	40297.0	154299.0	46208.0	38698.0	60260.0	58085.0	20422.0	17497.0	30363.0	20727.0	22154.0	53572.0	55159.0	50319.0	56866.0	30002.0	103310.0	82292.0	66616.0	138916.0	26826.0	87881.0	71332.0	92130.0	164336.0	24900.0	23203.0	20143.0	19386.0	16710.0	39075.0	31739.0	24006.0	33200.0	49541.0	20227.0	11904.0	25432.0	21314.0	24329.0	64727.0	70343.0	72315.0	47549.0	72657.0
Cellular Processes|Cell Motility|Bacterial motility proteins	92363.0	111620.0	74545.0	64689.0	82476.0	106964.0	174916.0	183535.0	158483.0	133747.0	71122.0	83379.0	82219.0	106597.0	65245.0	70467.0	64268.0	63145.0	59486.0	78046.0	128141.0	87053.0	432925.0	120960.0	97778.0	138496.0	150855.0	50514.0	48955.0	72481.0	61298.0	66253.0	110383.0	122970.0	111738.0	127614.0	69527.0	291482.0	242804.0	196009.0	424360.0	77178.0	257381.0	187671.0	244607.0	450452.0	66216.0	62880.0	61538.0	47819.0	45005.0	92790.0	84058.0	62053.0	66890.0	100063.0	61758.0	36143.0	79371.0	69600.0	73982.0	194957.0	220020.0	223351.0	149706.0	172864.0
Cellular Processes|Cell Motility|Cytoskeleton proteins	46592.0	50278.0	40037.0	36165.0	31085.0	33006.0	41771.0	46525.0	41026.0	31953.0	38502.0	43153.0	43864.0	50725.0	38451.0	28838.0	39646.0	44497.0	24898.0	34029.0	41787.0	44253.0	54143.0	41979.0	43600.0	75339.0	48668.0	30121.0	34914.0	51580.0	35869.0	36485.0	73511.0	64477.0	61247.0	62390.0	45042.0	56489.0	46813.0	38764.0	63842.0	32128.0	38877.0	29142.0	31872.0	48502.0	29024.0	24365.0	19928.0	24884.0	18639.0	41044.0	36701.0	31526.0	39893.0	61224.0	41118.0	23202.0	34340.0	36057.0	40065.0	39826.0	41969.0	73491.0	52868.0	56273.0
Cellular Processes|Cell Motility|Flagellar assembly	46198.0	56458.0	36792.0	31876.0	39062.0	48209.0	83617.0	89738.0	75857.0	66021.0	34565.0	41367.0	41095.0	53629.0	29179.0	35566.0	30938.0	29685.0	31646.0	39557.0	56929.0	36049.0	194621.0	39677.0	24530.0	59590.0	57974.0	21814.0	21121.0	33395.0	27857.0	30942.0	36868.0	43589.0	43396.0	51036.0	28237.0	127133.0	105729.0	83429.0	186690.0	35049.0	109727.0	76081.0	99465.0	187351.0	27548.0	27905.0	27397.0	19537.0	19535.0	44571.0	40464.0	29694.0	25343.0	37818.0	28279.0	16722.0	38337.0	31142.0	34293.0	78315.0	88736.0	90497.0	71453.0	74843.0
Cellular Processes|Cell Motility|Regulation of actin cytoskeleton	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Cellular Processes|Transport and Catabolism|Endocytosis	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0
Cellular Processes|Transport and Catabolism|Lysosome	48098.0	51847.0	35438.0	35291.0	12973.0	8774.0	10349.0	11548.0	10177.0	10300.0	38691.0	44755.0	47621.0	42387.0	28861.0	34307.0	45235.0	51677.0	31188.0	41866.0	48833.0	33283.0	25335.0	43763.0	47140.0	66181.0	43652.0	27711.0	38201.0	47075.0	32426.0	31177.0	23949.0	27310.0	23251.0	18848.0	34706.0	41144.0	42833.0	31094.0	48246.0	29069.0	12056.0	8079.0	8611.0	11957.0	9708.0	8299.0	6570.0	8667.0	6238.0	29226.0	27469.0	25154.0	19170.0	38789.0	32818.0	19722.0	33066.0	24903.0	30535.0	6328.0	5114.0	12420.0	11623.0	11810.0
Cellular Processes|Transport and Catabolism|Peroxisome	45115.0	52541.0	37550.0	34018.0	18375.0	34952.0	44773.0	47540.0	42191.0	41379.0	38400.0	41136.0	42673.0	46061.0	32148.0	33301.0	39772.0	44227.0	27655.0	37468.0	45041.0	36767.0	52811.0	34844.0	32398.0	62193.0	38534.0	27389.0	35654.0	45876.0	35546.0	39282.0	45531.0	42633.0	37106.0	39032.0	34125.0	58327.0	49723.0	41219.0	70745.0	32461.0	47971.0	33628.0	35905.0	52267.0	38012.0	30528.0	26073.0	29740.0	22756.0	35449.0	35512.0	29498.0	24660.0	42504.0	35063.0	20703.0	30506.0	31594.0	37613.0	23000.0	20763.0	49468.0	44903.0	42493.0
Cellular Processes|Transport and Catabolism|Phagosome	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Environmental Information Processing|Membrane Transport|ABC transporters	432920.0	492493.0	394681.0	351074.0	304528.0	582307.0	710232.0	794384.0	683249.0	577890.0	389075.0	412980.0	419238.0	555124.0	443634.0	320482.0	381067.0	411219.0	274603.0	347320.0	564684.0	501736.0	1200646.0	552759.0	494843.0	749736.0	621210.0	288940.0	328625.0	478603.0	380144.0	402077.0	880892.0	750000.0	717736.0	756895.0	419383.0	1007327.0	836973.0	758803.0	1395545.0	399447.0	1041132.0	759647.0	858930.0	1381099.0	556356.0	465259.0	378181.0	461483.0	348381.0	490542.0	478823.0	373944.0	446184.0	649693.0	392042.0	222233.0	354061.0	380247.0	436176.0	788386.0	778778.0	1039769.0	836565.0	789986.0
Environmental Information Processing|Membrane Transport|Bacterial secretion system	111915.0	128882.0	96491.0	85038.0	58190.0	105492.0	128466.0	131481.0	118698.0	103961.0	84523.0	90043.0	93809.0	110659.0	79395.0	75818.0	89133.0	96502.0	61905.0	85669.0	116246.0	82049.0	227304.0	119806.0	123597.0	145799.0	130990.0	68020.0	85699.0	113290.0	88768.0	82112.0	124652.0	106651.0	107388.0	114923.0	79120.0	233752.0	185100.0	143215.0	268733.0	77888.0	173662.0	122561.0	143757.0	233945.0	87188.0	79643.0	67366.0	76011.0	57441.0	93698.0	88434.0	73829.0	70836.0	112280.0	82622.0	47071.0	76805.0	78583.0	88801.0	131698.0	129065.0	174207.0	139690.0	120815.0
Environmental Information Processing|Membrane Transport|Phosphotransferase system (PTS)	58679.0	84435.0	88557.0	93446.0	74234.0	118951.0	143662.0	279080.0	190181.0	110673.0	62107.0	66646.0	63729.0	146987.0	140874.0	55275.0	82661.0	84963.0	63886.0	55899.0	116996.0	73212.0	273729.0	108625.0	69295.0	133127.0	115510.0	41282.0	53776.0	80502.0	81650.0	63760.0	242256.0	143287.0	175682.0	156617.0	114986.0	226058.0	179526.0	162038.0	328004.0	67073.0	256583.0	183792.0	213703.0	359002.0	87716.0	83481.0	61391.0	79115.0	61021.0	99704.0	124585.0	85222.0	127713.0	113705.0	83977.0	42338.0	95014.0	85459.0	81753.0	299525.0	290483.0	286990.0	287434.0	242355.0
Environmental Information Processing|Membrane Transport|Secretion system	203195.0	241955.0	183783.0	158629.0	110342.0	228609.0	293696.0	304852.0	270712.0	231946.0	160999.0	170555.0	177621.0	223133.0	160061.0	150168.0	172130.0	182767.0	122186.0	167881.0	249589.0	162871.0	581069.0	226245.0	211965.0	270804.0	265252.0	117708.0	141931.0	192282.0	159027.0	156756.0	254164.0	222865.0	222323.0	242107.0	148379.0	506998.0	413213.0	336313.0	666047.0	160439.0	429870.0	301003.0	363242.0	620629.0	181674.0	171871.0	144461.0	157447.0	120244.0	190497.0	170253.0	139306.0	143170.0	218798.0	159168.0	89936.0	151926.0	156061.0	175434.0	340541.0	343550.0	404429.0	316413.0	280422.0
Environmental Information Processing|Membrane Transport|Transporters	891659.0	1042895.0	863455.0	801943.0	669478.0	1211505.0	1519791.0	1847801.0	1529108.0	1275659.0	838506.0	901267.0	910292.0	1239148.0	1025125.0	720139.0	900775.0	982863.0	641820.0	779636.0	1220959.0	1110097.0	2188481.0	1133142.0	992914.0	1619544.0	1224471.0	617495.0	716045.0	1055351.0	840835.0	902498.0	2048257.0	1639809.0	1592744.0	1633572.0	1012228.0	1894146.0	1570892.0	1468688.0	2625255.0	836092.0	2067249.0	1469691.0	1638492.0	2584618.0	1201376.0	1012286.0	790062.0	999111.0	733719.0	1047985.0	1089872.0	833215.0	991626.0	1389752.0	860079.0	487519.0	782589.0	815317.0	927053.0	1577706.0	1537754.0	2190817.0	1906255.0	1815586.0
Environmental Information Processing|Signal Transduction|Calcium signaling pathway	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	20.0	7.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	499.0	6.0	60.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Environmental Information Processing|Signal Transduction|ErbB signaling pathway	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Environmental Information Processing|Signal Transduction|Hedgehog signaling pathway	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Environmental Information Processing|Signal Transduction|MAPK signaling pathway	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Environmental Information Processing|Signal Transduction|MAPK signaling pathway - yeast	8941.0	9937.0	7425.0	7286.0	6612.0	6812.0	8760.0	10591.0	8680.0	6940.0	8565.0	9501.0	9238.0	10259.0	7151.0	9943.0	11919.0	13448.0	8604.0	11214.0	13750.0	11957.0	11301.0	9492.0	9131.0	17520.0	10689.0	6446.0	8593.0	11056.0	7699.0	7758.0	14778.0	14412.0	13134.0	12019.0	10949.0	11812.0	11162.0	9586.0	14994.0	7841.0	10949.0	7886.0	8545.0	10940.0	6714.0	5851.0	4798.0	6150.0	4346.0	9448.0	9945.0	7633.0	9021.0	11655.0	8384.0	4947.0	7613.0	7118.0	8661.0	6182.0	5884.0	10398.0	7257.0	7907.0
Environmental Information Processing|Signal Transduction|Notch signaling pathway	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Environmental Information Processing|Signal Transduction|Phosphatidylinositol signaling system	19256.0	22118.0	16442.0	15079.0	9927.0	16803.0	20233.0	22589.0	19595.0	16883.0	18582.0	19663.0	20235.0	23706.0	17000.0	13478.0	16694.0	18306.0	11807.0	15095.0	19004.0	14516.0	23019.0	19220.0	20113.0	28713.0	20201.0	11475.0	15115.0	19600.0	15627.0	17370.0	22696.0	19499.0	18343.0	18224.0	14756.0	27435.0	22589.0	18667.0	33893.0	15600.0	21935.0	15867.0	16421.0	24584.0	17273.0	15175.0	12442.0	14809.0	10747.0	17344.0	16340.0	13571.0	12972.0	19231.0	18272.0	10375.0	15598.0	15784.0	18335.0	17392.0	15805.0	28093.0	24375.0	21427.0
Environmental Information Processing|Signal Transduction|TGF-beta signaling pathway	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Environmental Information Processing|Signal Transduction|Two-component system	235349.0	275571.0	196882.0	175638.0	142189.0	216272.0	305878.0	324607.0	283246.0	229981.0	190666.0	208532.0	214039.0	265632.0	187637.0	185736.0	211610.0	224969.0	155573.0	213679.0	306709.0	206037.0	673636.0	276886.0	259397.0	348020.0	324535.0	137290.0	161230.0	222445.0	174850.0	171875.0	287503.0	278810.0	263943.0	278788.0	189752.0	553500.0	467998.0	372150.0	743126.0	183446.0	454774.0	327137.0	408795.0	698983.0	154765.0	145152.0	124481.0	129244.0	106088.0	217676.0	203772.0	160951.0	164352.0	257304.0	189748.0	106510.0	178343.0	174950.0	192157.0	370611.0	380359.0	416603.0	325316.0	296941.0
Environmental Information Processing|Signal Transduction|VEGF signaling pathway	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Environmental Information Processing|Signal Transduction|Wnt signaling pathway	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Environmental Information Processing|Signal Transduction|mTOR signaling pathway	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Environmental Information Processing|Signaling Molecules and Interaction|Bacterial toxins	29617.0	33508.0	25809.0	23133.0	14411.0	23549.0	28763.0	32636.0	28068.0	24974.0	24547.0	25650.0	26219.0	30660.0	24538.0	16237.0	22297.0	25438.0	14856.0	18689.0	23865.0	21640.0	22196.0	27918.0	27001.0	44474.0	25502.0	18796.0	23880.0	29434.0	23778.0	26117.0	45844.0	29914.0	32612.0	30508.0	26780.0	27439.0	25039.0	23502.0	35875.0	20017.0	28119.0	19560.0	20064.0	27863.0	24829.0	21446.0	15218.0	22324.0	15659.0	22321.0	25800.0	20300.0	28265.0	30286.0	23843.0	13684.0	21052.0	22607.0	26009.0	21819.0	20917.0	44434.0	34098.0	34932.0
Environmental Information Processing|Signaling Molecules and Interaction|CAM ligands	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Environmental Information Processing|Signaling Molecules and Interaction|Cellular antigens	17080.0	19133.0	13589.0	12336.0	3168.0	5794.0	7034.0	8026.0	6854.0	6883.0	13298.0	13851.0	14403.0	15130.0	10187.0	8716.0	11529.0	13111.0	7479.0	10874.0	13485.0	8384.0	14420.0	10364.0	10172.0	19658.0	12890.0	8541.0	11925.0	14805.0	10726.0	11994.0	7512.0	8306.0	6319.0	6033.0	9131.0	18519.0	18560.0	14522.0	25539.0	11374.0	11965.0	8244.0	10271.0	13960.0	5899.0	5459.0	4571.0	5241.0	3907.0	10214.0	10452.0	9450.0	5175.0	10635.0	12111.0	7129.0	11028.0	10280.0	13039.0	6116.0	6034.0	7688.0	6590.0	5932.0
Environmental Information Processing|Signaling Molecules and Interaction|Cytokine receptors	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Environmental Information Processing|Signaling Molecules and Interaction|Cytokine-cytokine receptor interaction	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Environmental Information Processing|Signaling Molecules and Interaction|ECM-receptor interaction	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Environmental Information Processing|Signaling Molecules and Interaction|G protein-coupled receptors	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	5.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	13.0
Environmental Information Processing|Signaling Molecules and Interaction|GTP-binding proteins	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Environmental Information Processing|Signaling Molecules and Interaction|Glycan bindng proteins	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Environmental Information Processing|Signaling Molecules and Interaction|Ion channels	4065.0	5071.0	4754.0	4153.0	2789.0	7228.0	7674.0	8280.0	7340.0	7265.0	4236.0	4733.0	4953.0	6524.0	5994.0	3672.0	4414.0	4737.0	3051.0	3417.0	5307.0	3078.0	10694.0	6950.0	6804.0	6384.0	6033.0	2512.0	3272.0	4312.0	4432.0	4936.0	6207.0	4387.0	3649.0	4115.0	2582.0	8748.0	7512.0	7482.0	13422.0	3809.0	11754.0	8287.0	8735.0	13771.0	8350.0	7368.0	5472.0	7318.0	5092.0	4917.0	4647.0	3308.0	3059.0	5878.0	5420.0	3082.0	4672.0	5565.0	4604.0	8707.0	6920.0	12040.0	11805.0	9720.0
Environmental Information Processing|Signaling Molecules and Interaction|Neuroactive ligand-receptor interaction	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Genetic Information Processing|Folding, Sorting and Degradation|Chaperones and folding catalysts	199478.0	222691.0	167706.0	150276.0	99781.0	141123.0	169022.0	180862.0	160410.0	136809.0	157622.0	172953.0	178259.0	205612.0	148101.0	131803.0	165344.0	182147.0	113946.0	153777.0	197203.0	148762.0	295274.0	173792.0	174882.0	274778.0	205219.0	117408.0	148501.0	199924.0	146142.0	145003.0	208577.0	191320.0	180690.0	185021.0	146187.0	318396.0	269632.0	210059.0	382047.0	137341.0	222773.0	164335.0	183997.0	297132.0	131930.0	115155.0	99465.0	111557.0	83963.0	160929.0	148573.0	124986.0	125552.0	199381.0	156399.0	88748.0	140319.0	134493.0	156719.0	180965.0	175333.0	246319.0	203269.0	185899.0
Genetic Information Processing|Folding, Sorting and Degradation|Proteasome	8914.0	10648.0	7511.0	6957.0	3332.0	8305.0	12173.0	12919.0	11544.0	11471.0	7826.0	8659.0	9052.0	9039.0	6524.0	8400.0	9860.0	10984.0	6278.0	9231.0	10827.0	9996.0	10906.0	8466.0	7887.0	13351.0	8158.0	6139.0	7306.0	9771.0	7850.0	9099.0	14682.0	12562.0	11851.0	11981.0	9687.0	12063.0	9425.0	8625.0	14101.0	6894.0	11507.0	7855.0	8557.0	12471.0	9748.0	7491.0	6274.0	7550.0	5669.0	6946.0	7191.0	6057.0	6833.0	10289.0	6562.0	3986.0	6093.0	6602.0	7645.0	4252.0	4624.0	13794.0	10874.0	11097.0
Genetic Information Processing|Folding, Sorting and Degradation|Protein export	102148.0	113597.0	88840.0	79566.0	61557.0	91344.0	102735.0	113059.0	99246.0	81546.0	81479.0	85876.0	87998.0	103398.0	76554.0	73327.0	89108.0	98768.0	61982.0	79942.0	97803.0	83808.0	134118.0	88488.0	87941.0	143009.0	99785.0	65290.0	83691.0	109212.0	82376.0	77632.0	136238.0	111346.0	109295.0	111123.0	83975.0	161891.0	126947.0	100948.0	169702.0	68727.0	116777.0	85255.0	91740.0	141384.0	82378.0	74717.0	59253.0	74202.0	53981.0	88564.0	83604.0	67149.0	74558.0	111764.0	80634.0	45654.0	72205.0	74524.0	86386.0	98095.0	92580.0	154615.0	117717.0	113687.0
Genetic Information Processing|Folding, Sorting and Degradation|Protein processing in endoplasmic reticulum	16213.0	17610.0	12828.0	11955.0	7293.0	5520.0	9324.0	10416.0	9008.0	6984.0	13063.0	14781.0	15014.0	16779.0	11964.0	8090.0	11127.0	12398.0	7617.0	10010.0	11978.0	8499.0	11591.0	14348.0	15489.0	23379.0	15252.0	8903.0	12001.0	15982.0	11351.0	11260.0	12036.0	10587.0	9375.0	9537.0	10359.0	17079.0	15560.0	11254.0	19959.0	10208.0	8382.0	5868.0	6635.0	9971.0	5267.0	4431.0	3947.0	4479.0	3289.0	10316.0	11596.0	9948.0	7564.0	13052.0	12989.0	7283.0	10905.0	9714.0	11290.0	8234.0	9018.0	14215.0	12251.0	9902.0
Genetic Information Processing|Folding, Sorting and Degradation|RNA degradation	90663.0	101939.0	78521.0	70361.0	46958.0	74059.0	92262.0	99938.0	88071.0	75815.0	75261.0	80734.0	82918.0	94252.0	68626.0	61452.0	75801.0	84060.0	52588.0	68934.0	84330.0	71658.0	118897.0	85689.0	86865.0	130936.0	91904.0	55781.0	71398.0	93798.0	71446.0	72988.0	112517.0	95046.0	91146.0	93927.0	72159.0	128695.0	107340.0	87712.0	150765.0	62806.0	101258.0	73522.0	79718.0	121217.0	72704.0	61139.0	51324.0	60985.0	45831.0	73795.0	73957.0	60080.0	65466.0	94178.0	73161.0	41918.0	64090.0	65954.0	76656.0	75521.0	74683.0	126948.0	102005.0	97012.0
Genetic Information Processing|Folding, Sorting and Degradation|Sulfur relay system	42431.0	48114.0	36807.0	31551.0	23011.0	44354.0	54014.0	53863.0	49415.0	41816.0	36684.0	39034.0	41072.0	47144.0	31085.0	34294.0	39146.0	41536.0	26785.0	38313.0	50305.0	36387.0	109598.0	49804.0	50763.0	61204.0	57407.0	22779.0	24441.0	38458.0	28274.0	30945.0	53253.0	51826.0	49177.0	53288.0	34193.0	88247.0	74293.0	61791.0	123332.0	33145.0	77678.0	58970.0	66475.0	113370.0	40094.0	34116.0	29954.0	31596.0	25071.0	39557.0	29854.0	27472.0	29688.0	49870.0	34258.0	19570.0	33371.0	31112.0	36129.0	64336.0	65940.0	81225.0	57464.0	52121.0
Genetic Information Processing|Folding, Sorting and Degradation|Ubiquitin system	6397.0	7469.0	5096.0	4557.0	627.0	4727.0	6502.0	6693.0	6104.0	6524.0	5586.0	5452.0	5867.0	5944.0	3825.0	5264.0	5709.0	6252.0	3850.0	5317.0	6100.0	4282.0	6998.0	5180.0	5087.0	6996.0	4867.0	2721.0	3348.0	4919.0	3801.0	5612.0	5459.0	4880.0	3966.0	4215.0	3968.0	7123.0	6479.0	6221.0	11107.0	4830.0	7636.0	5299.0	5565.0	8137.0	6092.0	4489.0	3788.0	4284.0	3376.0	4201.0	3940.0	3880.0	2341.0	4382.0	4521.0	2728.0	3596.0	3764.0	4888.0	2237.0	2025.0	6051.0	5993.0	5116.0
Genetic Information Processing|Replication and Repair|Base excision repair	63533.0	71736.0	59488.0	53612.0	46229.0	62726.0	72874.0	83594.0	72075.0	58976.0	55502.0	60846.0	62329.0	76008.0	59743.0	51781.0	64594.0	71367.0	44845.0	56552.0	72269.0	61213.0	111221.0	73228.0	74222.0	105767.0	78857.0	43925.0	53782.0	72543.0	56004.0	54261.0	103654.0	84074.0	83016.0	83475.0	61115.0	109700.0	90205.0	74484.0	131679.0	47900.0	91552.0	65536.0	71915.0	114128.0	57500.0	51358.0	41329.0	50777.0	37048.0	61111.0	59245.0	45916.0	57554.0	79960.0	59746.0	33960.0	54646.0	55653.0	60377.0	78916.0	75300.0	113560.0	93736.0	88333.0
Genetic Information Processing|Replication and Repair|Chromosome	263133.0	295919.0	232789.0	207884.0	156233.0	229223.0	276568.0	303135.0	265399.0	229274.0	218324.0	237456.0	243310.0	288210.0	212825.0	179073.0	227562.0	250961.0	154699.0	206259.0	264265.0	220663.0	406248.0	231363.0	224578.0	379040.0	270091.0	164653.0	202892.0	278387.0	207971.0	210657.0	348392.0	298717.0	285276.0	296447.0	220559.0	399682.0	339722.0	280121.0	499631.0	187486.0	331284.0	243807.0	269226.0	423263.0	215761.0	187093.0	157706.0	185229.0	138403.0	232815.0	221655.0	180931.0	195382.0	297742.0	219143.0	124696.0	191743.0	196580.0	225372.0	253835.0	244967.0	401005.0	331433.0	315952.0
Genetic Information Processing|Replication and Repair|DNA repair and recombination proteins	484368.0	550363.0	435618.0	386492.0	291062.0	455426.0	542018.0	598740.0	523625.0	453228.0	408253.0	438849.0	451461.0	537468.0	405998.0	345412.0	432698.0	478571.0	295886.0	384484.0	489164.0	427229.0	717841.0	456646.0	452620.0	714303.0	504943.0	310596.0	384374.0	517092.0	398778.0	408703.0	702142.0	577100.0	558335.0	576425.0	415256.0	742666.0	604889.0	510469.0	893146.0	355161.0	622527.0	448532.0	485982.0	754112.0	437137.0	381692.0	310493.0	379670.0	279797.0	435030.0	415252.0	334804.0	377924.0	554827.0	413666.0	236344.0	361297.0	383018.0	436898.0	480696.0	457944.0	783441.0	651918.0	612361.0
Genetic Information Processing|Replication and Repair|DNA replication	116992.0	131693.0	102766.0	90958.0	67552.0	101471.0	116714.0	128934.0	112882.0	98861.0	94236.0	100192.0	102778.0	122185.0	92029.0	85699.0	107258.0	119266.0	72689.0	95023.0	118789.0	104825.0	148616.0	99504.0	98828.0	162485.0	111676.0	74198.0	93791.0	124037.0	95229.0	94172.0	161521.0	138947.0	132770.0	133147.0	98378.0	171316.0	137948.0	113585.0	190161.0	81797.0	129119.0	94894.0	100913.0	157548.0	97784.0	86388.0	69687.0	86475.0	63599.0	105909.0	96635.0	77743.0	92015.0	130168.0	93858.0	53389.0	82965.0	87991.0	99873.0	100616.0	93863.0	172269.0	142835.0	135918.0
Genetic Information Processing|Replication and Repair|DNA replication proteins	212332.0	237590.0	185810.0	166056.0	128646.0	179102.0	208422.0	231153.0	201757.0	178289.0	170493.0	183888.0	188520.0	220692.0	164844.0	153737.0	193497.0	215172.0	131540.0	173879.0	217848.0	188440.0	291074.0	186047.0	183871.0	303081.0	211965.0	135350.0	169538.0	227386.0	170338.0	168657.0	284418.0	248609.0	236151.0	238041.0	184542.0	315560.0	260093.0	210639.0	359346.0	146015.0	240836.0	176175.0	188963.0	296088.0	173871.0	151467.0	124472.0	150514.0	111317.0	191680.0	177827.0	143006.0	164551.0	236334.0	167349.0	95528.0	149108.0	153389.0	175750.0	175816.0	162580.0	299156.0	249239.0	241626.0
Genetic Information Processing|Replication and Repair|Homologous recombination	168783.0	190095.0	145543.0	129256.0	92978.0	151916.0	179990.0	196512.0	173076.0	151111.0	140570.0	149522.0	153761.0	180724.0	135305.0	111404.0	138866.0	153753.0	94994.0	123531.0	158026.0	142008.0	220499.0	143560.0	140651.0	239645.0	161979.0	105282.0	131462.0	177056.0	135955.0	141069.0	234753.0	189053.0	184253.0	190514.0	137251.0	243649.0	196703.0	166473.0	286746.0	121990.0	199336.0	145101.0	154391.0	236272.0	150606.0	129474.0	105529.0	130242.0	95744.0	147199.0	138687.0	113105.0	125615.0	187045.0	140392.0	80417.0	120649.0	129137.0	150504.0	150074.0	143002.0	260324.0	211925.0	200950.0
Genetic Information Processing|Replication and Repair|Mismatch repair	136486.0	151877.0	119987.0	106321.0	80684.0	114993.0	131335.0	146748.0	127852.0	109875.0	108419.0	117183.0	119825.0	141222.0	106094.0	93381.0	118793.0	132180.0	80398.0	105512.0	133242.0	120018.0	183331.0	120694.0	120927.0	195100.0	136680.0	85280.0	105335.0	144060.0	107312.0	105752.0	187838.0	163129.0	154375.0	156790.0	114125.0	203333.0	164346.0	134264.0	228105.0	93706.0	151621.0	112869.0	120588.0	190584.0	109896.0	97067.0	79319.0	97611.0	71828.0	123480.0	111604.0	90660.0	106845.0	155244.0	107930.0	61494.0	96220.0	100084.0	113985.0	120714.0	114056.0	200879.0	161041.0	156373.0
Genetic Information Processing|Replication and Repair|Non-homologous end-joining	368.0	360.0	293.0	588.0	2189.0	1069.0	1725.0	2196.0	1975.0	51.0	237.0	495.0	617.0	196.0	197.0	10.0	8.0	12.0	23.0	2.0	7.0	541.0	1009.0	5555.0	6871.0	1810.0	2829.0	39.0	151.0	108.0	230.0	46.0	2363.0	827.0	1529.0	1433.0	542.0	77.0	32.0	203.0	4.0	90.0	848.0	768.0	620.0	708.0	928.0	474.0	634.0	512.0	381.0	215.0	303.0	40.0	221.0	1084.0	417.0	146.0	224.0	450.0	286.0	2707.0	3296.0	3292.0	455.0	126.0
Genetic Information Processing|Replication and Repair|Nucleotide excision repair	64194.0	73410.0	59390.0	53042.0	37487.0	65365.0	79834.0	88248.0	77268.0	68044.0	56885.0	61246.0	62722.0	72747.0	56098.0	42076.0	53129.0	59349.0	36556.0	45779.0	57662.0	56442.0	82376.0	67280.0	68540.0	100230.0	67799.0	43404.0	53573.0	72505.0	56449.0	59271.0	105133.0	78185.0	76954.0	80836.0	56053.0	89920.0	71638.0	64563.0	107422.0	48435.0	82635.0	59164.0	62255.0	92848.0	66887.0	55757.0	45014.0	56401.0	41347.0	56771.0	58012.0	46755.0	52296.0	77648.0	56749.0	32923.0	49902.0	53985.0	61007.0	60754.0	59049.0	113787.0	91071.0	89091.0
Genetic Information Processing|Transcription|Basal transcription factors	1.0	1.0	1.0	0.0	0.0	24.0	0.0	0.0	0.0	0.0	2.0	0.0	1.0	3.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.0	0.0	0.0	0.0	1.0	0.0	5.0	3.0	1.0	2.0	0.0	3.0	2.0	2.0	2.0	0.0	12.0	2.0	0.0	0.0	0.0	3.0	5.0	3.0	38.0	2.0	50.0	6.0	32.0	1.0	6.0	0.0	2.0	0.0	3.0	2.0	0.0	0.0	0.0	0.0	223.0	194.0	24.0	6.0	8.0
Genetic Information Processing|Transcription|RNA polymerase	24531.0	28396.0	24557.0	21144.0	16997.0	28796.0	32420.0	35494.0	31162.0	27192.0	21936.0	23091.0	23634.0	29182.0	23003.0	18072.0	23477.0	26213.0	15752.0	19702.0	24699.0	24147.0	35145.0	24776.0	24842.0	37971.0	25831.0	17322.0	21151.0	28492.0	22473.0	22775.0	44673.0	34810.0	33193.0	34427.0	22798.0	39450.0	29326.0	26127.0	43001.0	19020.0	34958.0	25067.0	26264.0	38918.0	27706.0	24708.0	19086.0	24798.0	17865.0	25114.0	23313.0	18354.0	23023.0	33271.0	22770.0	13023.0	19710.0	22090.0	24755.0	28270.0	25887.0	48134.0	40386.0	38739.0
Genetic Information Processing|Transcription|Spliceosome	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Genetic Information Processing|Transcription|Transcription factors	216149.0	259030.0	198575.0	183199.0	180488.0	263207.0	335896.0	399228.0	333453.0	272847.0	193802.0	212777.0	215855.0	284389.0	225472.0	181918.0	214745.0	230569.0	159352.0	200789.0	314694.0	256126.0	656808.0	275381.0	239428.0	381635.0	325538.0	141740.0	158618.0	229601.0	182262.0	192551.0	429686.0	363862.0	362549.0	368221.0	234291.0	526659.0	440403.0	384392.0	738890.0	196108.0	512703.0	368035.0	431358.0	720153.0	226313.0	200233.0	161281.0	189016.0	144380.0	251616.0	241306.0	187253.0	234223.0	325722.0	199739.0	114370.0	197923.0	196492.0	210355.0	408056.0	407439.0	504657.0	403480.0	391058.0
Genetic Information Processing|Transcription|Transcription machinery	158703.0	173245.0	132390.0	124212.0	103409.0	95015.0	122573.0	134416.0	118441.0	95352.0	139283.0	157386.0	163022.0	172823.0	124267.0	120555.0	154212.0	173269.0	105612.0	141609.0	167521.0	146904.0	203252.0	176388.0	187364.0	258995.0	185439.0	102165.0	123994.0	167461.0	117408.0	123526.0	192974.0	175894.0	168815.0	167182.0	153167.0	206556.0	181600.0	137755.0	236950.0	110642.0	131251.0	98737.0	108293.0	165175.0	90858.0	78098.0	67686.0	78037.0	58344.0	135466.0	133237.0	105977.0	117171.0	187425.0	133069.0	76446.0	126029.0	113678.0	130794.0	114817.0	117486.0	189177.0	133626.0	144032.0
Genetic Information Processing|Translation|Aminoacyl-tRNA biosynthesis	171116.0	194148.0	162555.0	142745.0	111915.0	187477.0	214481.0	239285.0	208677.0	179578.0	149562.0	158607.0	161395.0	194489.0	151100.0	123763.0	156878.0	175230.0	106512.0	134104.0	168158.0	164306.0	236945.0	173210.0	173376.0	263319.0	181267.0	118576.0	145793.0	194251.0	153110.0	154135.0	300163.0	233599.0	227066.0	230967.0	157169.0	272048.0	204388.0	178522.0	293511.0	129790.0	233182.0	168887.0	179199.0	264759.0	180855.0	158873.0	124934.0	161364.0	116641.0	162950.0	157656.0	123812.0	152789.0	221370.0	152031.0	87562.0	134099.0	148221.0	166703.0	180052.0	169446.0	314648.0	255867.0	256267.0
Genetic Information Processing|Translation|RNA transport	13804.0	15141.0	13990.0	12206.0	12827.0	12290.0	12627.0	15164.0	12862.0	9885.0	11885.0	13407.0	13606.0	17976.0	13338.0	12115.0	15427.0	16693.0	10238.0	13271.0	14931.0	14668.0	25422.0	15003.0	16114.0	23538.0	18269.0	10799.0	12145.0	17319.0	11447.0	9369.0	24459.0	21546.0	22478.0	23406.0	15270.0	21209.0	18580.0	14421.0	27780.0	9273.0	16691.0	13136.0	14466.0	24099.0	9713.0	10460.0	8069.0	9258.0	6697.0	16152.0	12394.0	10127.0	15678.0	21400.0	12586.0	6841.0	12847.0	11455.0	12017.0	19881.0	17698.0	21287.0	20650.0	21334.0
Genetic Information Processing|Translation|Ribosome	376873.0	425869.0	346504.0	305020.0	232217.0	368910.0	425187.0	469585.0	411415.0	360117.0	317140.0	339064.0	348428.0	410548.0	314618.0	269020.0	341775.0	381916.0	231860.0	297067.0	368199.0	348135.0	484043.0	343079.0	342282.0	554335.0	371674.0	254455.0	317913.0	420832.0	326315.0	324952.0	589102.0	474574.0	455455.0	465976.0	332281.0	559154.0	430875.0	368310.0	607013.0	273379.0	463367.0	334107.0	350607.0	514650.0	363727.0	317306.0	254040.0	321641.0	233568.0	345848.0	326039.0	261001.0	308315.0	456725.0	319302.0	183749.0	281609.0	305085.0	345748.0	348876.0	327193.0	618583.0	508371.0	496067.0
Genetic Information Processing|Translation|Ribosome Biogenesis	217473.0	247658.0	196670.0	173945.0	140759.0	229085.0	260504.0	286420.0	250860.0	217583.0	186920.0	202719.0	208448.0	248543.0	185504.0	162650.0	199759.0	219297.0	138873.0	181133.0	235717.0	202646.0	385607.0	213471.0	207445.0	327968.0	243453.0	145685.0	175670.0	238660.0	182721.0	185118.0	340238.0	278628.0	277407.0	284447.0	198291.0	378972.0	303471.0	255836.0	463412.0	165734.0	328281.0	240054.0	260473.0	407975.0	218922.0	191567.0	158013.0	189536.0	139824.0	205420.0	188390.0	152849.0	187194.0	269513.0	186505.0	107037.0	166888.0	174884.0	202248.0	248344.0	232753.0	373264.0	312633.0	299779.0
Genetic Information Processing|Translation|Ribosome biogenesis in eukaryotes	11419.0	13478.0	10180.0	8644.0	4844.0	11539.0	14429.0	15495.0	13740.0	13139.0	8811.0	9297.0	9631.0	11111.0	8162.0	7332.0	8703.0	9652.0	6058.0	7847.0	9116.0	9155.0	12766.0	8516.0	8100.0	13959.0	8416.0	6968.0	8608.0	10806.0	9167.0	10213.0	15670.0	12286.0	11893.0	12483.0	8290.0	12360.0	9583.0	9362.0	15104.0	7761.0	15126.0	10826.0	11280.0	14197.0	12884.0	10399.0	8648.0	10300.0	7728.0	8878.0	8664.0	7168.0	7639.0	11004.0	8357.0	4954.0	7489.0	8821.0	9928.0	8250.0	8033.0	17744.0	15444.0	14361.0
Genetic Information Processing|Translation|Translation factors	85149.0	95309.0	77953.0	69036.0	52517.0	78757.0	89930.0	99479.0	87051.0	75035.0	70832.0	76673.0	78729.0	92133.0	69861.0	61895.0	79657.0	88887.0	53779.0	70489.0	87303.0	77281.0	119336.0	80989.0	81602.0	127512.0	89178.0	57035.0	71077.0	95403.0	71994.0	70031.0	126581.0	103629.0	101083.0	102717.0	77402.0	130599.0	104641.0	86296.0	146453.0	60304.0	103621.0	75996.0	81088.0	123020.0	75660.0	66244.0	54085.0	66672.0	48736.0	76143.0	72529.0	58265.0	69842.0	101215.0	71785.0	41203.0	63672.0	66357.0	75882.0	79846.0	75697.0	134196.0	109719.0	104634.0
Genetic Information Processing|Translation|mRNA surveillance pathway	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Human Diseases|Cancers|Bladder cancer	1054.0	1458.0	955.0	781.0	15.0	1394.0	1992.0	1844.0	1695.0	1687.0	845.0	920.0	1015.0	1176.0	602.0	837.0	843.0	810.0	616.0	1052.0	1503.0	603.0	4451.0	703.0	386.0	992.0	1230.0	422.0	431.0	684.0	602.0	829.0	415.0	648.0	819.0	1021.0	441.0	3300.0	2805.0	2257.0	5059.0	933.0	2817.0	1864.0	2485.0	4627.0	748.0	750.0	737.0	510.0	508.0	909.0	604.0	636.0	413.0	655.0	732.0	429.0	718.0	586.0	824.0	1891.0	1857.0	1950.0	1862.0	1081.0
Human Diseases|Cancers|Chronic myeloid leukemia	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Human Diseases|Cancers|Colorectal cancer	0.0	0.0	0.0	0.0	0.0	8.0	4.0	1.0	2.0	0.0	0.0	0.0	0.0	2.0	6.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	2.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2400.0	737.0	0.0	2.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.0	0.0	2.0	0.0	1.0	0.0	1.0	0.0
Human Diseases|Cancers|Glioma	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Human Diseases|Cancers|Pancreatic cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Human Diseases|Cancers|Pathways in cancer	6101.0	6742.0	5514.0	5008.0	3637.0	4286.0	5219.0	5537.0	4994.0	3823.0	5119.0	5985.0	6427.0	7214.0	5117.0	6917.0	9066.0	9977.0	5486.0	8509.0	9815.0	6927.0	12709.0	7642.0	8131.0	9713.0	8375.0	4175.0	4810.0	6991.0	4998.0	4374.0	7277.0	8569.0	8147.0	8026.0	7431.0	17501.0	11955.0	6919.0	13254.0	4065.0	6619.0	5222.0	6269.0	10959.0	2722.0	2443.0	2620.0	2320.0	2037.0	5105.0	4662.0	3713.0	4745.0	7358.0	5149.0	2784.0	5056.0	4361.0	4831.0	7394.0	7788.0	9461.0	7370.0	6020.0
Human Diseases|Cancers|Prostate cancer	4885.0	5322.0	3785.0	3939.0	4103.0	1901.0	3206.0	3255.0	2990.0	2037.0	4253.0	5398.0	5802.0	5041.0	3296.0	7584.0	9784.0	11008.0	6309.0	9545.0	10783.0	7980.0	8765.0	5715.0	5738.0	8687.0	6555.0	4268.0	4900.0	6291.0	4254.0	3377.0	7035.0	8240.0	7798.0	7245.0	8786.0	9264.0	7301.0	4438.0	8102.0	3071.0	3241.0	2597.0	3377.0	5959.0	923.0	1051.0	1214.0	1100.0	925.0	3954.0	3260.0	2799.0	4143.0	7327.0	3617.0	2140.0	4523.0	3328.0	3345.0	3854.0	4448.0	5784.0	2683.0	3185.0
Human Diseases|Cancers|Renal cell carcinoma	1273.0	1520.0	1975.0	1489.0	521.0	2377.0	2022.0	2281.0	2012.0	1788.0	1131.0	1050.0	1225.0	2335.0	1957.0	1533.0	2220.0	2325.0	1081.0	1714.0	2066.0	711.0	4645.0	2252.0	2608.0	1258.0	2165.0	558.0	742.0	1218.0	1174.0	1165.0	761.0	1369.0	1082.0	1275.0	700.0	6018.0	4145.0	2578.0	5151.0	1007.0	3378.0	2625.0	2892.0	5000.0	1799.0	1392.0	1406.0	1220.0	1112.0	1153.0	1411.0	916.0	608.0	753.0	1675.0	820.0	1203.0	1267.0	1504.0	3540.0	3339.0	3677.0	4687.0	2835.0
Human Diseases|Cancers|Small cell lung cancer	0.0	0.0	0.0	0.0	0.0	8.0	4.0	1.0	2.0	0.0	0.0	0.0	0.0	2.0	6.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	2.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2400.0	737.0	0.0	2.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.0	0.0	2.0	0.0	1.0	0.0	1.0	0.0
Human Diseases|Cardiovascular Diseases|Arrhythmogenic right ventricular cardiomyopathy (ARVC)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Human Diseases|Cardiovascular Diseases|Dilated cardiomyopathy (DCM)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Human Diseases|Cardiovascular Diseases|Hypertrophic cardiomyopathy (HCM)	0.0	0.0	0.0	0.0	0.0	7.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Human Diseases|Cardiovascular Diseases|Viral myocarditis	0.0	0.0	0.0	0.0	0.0	8.0	4.0	1.0	2.0	0.0	0.0	0.0	0.0	2.0	6.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	2.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2400.0	737.0	0.0	2.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.0	0.0	2.0	0.0	1.0	0.0	1.0	0.0
Human Diseases|Immune System Diseases|Primary immunodeficiency	8054.0	9565.0	7757.0	7119.0	3970.0	9205.0	9656.0	11429.0	9515.0	8612.0	7713.0	8379.0	8579.0	10579.0	8318.0	6951.0	8731.0	9591.0	5941.0	7583.0	10124.0	8824.0	12273.0	6579.0	5243.0	13047.0	8056.0	6016.0	7470.0	9850.0	7706.0	7648.0	13137.0	12403.0	11338.0	11249.0	6962.0	12251.0	10968.0	10045.0	16985.0	6875.0	11754.0	8521.0	9368.0	15224.0	7880.0	7352.0	5812.0	7098.0	5284.0	9348.0	8096.0	6447.0	7854.0	11223.0	7456.0	4167.0	7270.0	7050.0	7804.0	10758.0	8947.0	15357.0	13232.0	12535.0
Human Diseases|Immune System Diseases|Rheumatoid arthritis	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Human Diseases|Immune System Diseases|Systemic lupus erythematosus	2.0	7.0	6.0	16.0	0.0	32.0	0.0	0.0	0.0	0.0	0.0	29.0	3.0	4.0	0.0	0.0	0.0	0.0	2.0	0.0	0.0	0.0	0.0	1516.0	2140.0	245.0	779.0	0.0	2.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	6.0	3.0	2.0	1.0	13.0	5.0	125.0	16.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Human Diseases|Infectious Diseases|African trypanosomiasis	3093.0	4167.0	2935.0	2500.0	122.0	4699.0	8026.0	8004.0	7285.0	6453.0	2764.0	2781.0	2940.0	3259.0	2335.0	2346.0	2353.0	2475.0	1553.0	2271.0	3046.0	2667.0	6203.0	3894.0	3751.0	3787.0	3022.0	1682.0	2114.0	2715.0	2815.0	3777.0	6174.0	3699.0	4187.0	4629.0	1990.0	4797.0	3997.0	4591.0	8059.0	2940.0	7353.0	4685.0	5430.0	8239.0	5158.0	3944.0	3263.0	3721.0	2875.0	2440.0	2830.0	2273.0	1965.0	3105.0	2686.0	1572.0	1709.0	2741.0	3233.0	3655.0	4066.0	8107.0	6248.0	5129.0
Human Diseases|Infectious Diseases|Amoebiasis	3134.0	3332.0	2293.0	2258.0	1030.0	246.0	805.0	667.0	670.0	34.0	742.0	1187.0	1336.0	1038.0	1087.0	887.0	1100.0	1254.0	632.0	928.0	1429.0	1962.0	1070.0	2702.0	3098.0	2461.0	1962.0	1196.0	1885.0	2217.0	1451.0	562.0	1901.0	3175.0	2197.0	1796.0	250.0	3127.0	3453.0	1955.0	477.0	640.0	231.0	107.0	191.0	249.0	13.0	77.0	241.0	124.0	104.0	2432.0	2665.0	1389.0	1316.0	2673.0	788.0	254.0	731.0	748.0	571.0	1548.0	1842.0	1631.0	241.0	689.0
Human Diseases|Infectious Diseases|Bacterial invasion of epithelial cells	1215.0	1693.0	1079.0	897.0	17.0	2329.0	2340.0	2175.0	1994.0	1999.0	1187.0	1084.0	1189.0	1295.0	414.0	979.0	975.0	943.0	719.0	1329.0	652.0	715.0	1432.0	427.0	316.0	1156.0	374.0	444.0	505.0	802.0	704.0	987.0	417.0	1326.0	1050.0	1253.0	552.0	173.0	143.0	286.0	602.0	766.0	170.0	83.0	112.0	93.0	906.0	881.0	851.0	661.0	798.0	1134.0	586.0	502.0	389.0	368.0	838.0	483.0	648.0	669.0	1267.0	1008.0	281.0	2199.0	2174.0	1312.0
Human Diseases|Infectious Diseases|Chagas disease (American trypanosomiasis)	3093.0	4167.0	2935.0	2500.0	122.0	4284.0	6453.0	6674.0	5977.0	6406.0	2763.0	2781.0	2940.0	3258.0	2284.0	2346.0	2349.0	2476.0	1553.0	2270.0	3041.0	2493.0	5872.0	3757.0	3708.0	3686.0	2984.0	1658.0	2044.0	2670.0	2611.0	3771.0	4482.0	3329.0	3212.0	3636.0	1919.0	4766.0	3977.0	4398.0	8059.0	2851.0	6919.0	4480.0	5060.0	7758.0	5158.0	3944.0	3263.0	3721.0	2874.0	2400.0	2574.0	2266.0	1761.0	2493.0	2273.0	1427.0	1521.0	2332.0	2980.0	1906.0	1862.0	5930.0	5956.0	5035.0
Human Diseases|Infectious Diseases|Epithelial cell signaling in Helicobacter pylori infection	11854.0	13206.0	9214.0	8774.0	7959.0	9307.0	10802.0	12724.0	10746.0	8837.0	10118.0	11091.0	11241.0	11982.0	8498.0	7748.0	8909.0	9903.0	6885.0	8963.0	13027.0	11135.0	23258.0	12294.0	12664.0	18902.0	15292.0	8104.0	9662.0	13035.0	9186.0	9083.0	16997.0	15290.0	14814.0	14852.0	11108.0	20954.0	18906.0	15579.0	29108.0	9077.0	17337.0	12689.0	14966.0	24735.0	7830.0	7151.0	6109.0	7305.0	5480.0	10624.0	10427.0	8427.0	10147.0	15265.0	8726.0	5177.0	8327.0	8224.0	10368.0	10322.0	10554.0	15405.0	10099.0	11663.0
Human Diseases|Infectious Diseases|Hepatitis C	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Human Diseases|Infectious Diseases|Influenza A	0.0	0.0	0.0	0.0	0.0	8.0	4.0	1.0	2.0	0.0	0.0	0.0	0.0	2.0	6.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	2.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2400.0	737.0	0.0	2.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.0	0.0	2.0	0.0	1.0	0.0	1.0	0.0
Human Diseases|Infectious Diseases|Leishmaniasis	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Human Diseases|Infectious Diseases|Measles	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Human Diseases|Infectious Diseases|Pathogenic Escherichia coli infection	780.0	1125.0	620.0	560.0	5.0	1010.0	1650.0	1570.0	1405.0	1480.0	610.0	760.0	825.0	770.0	170.0	640.0	635.0	625.0	495.0	1340.0	495.0	485.0	1275.0	435.0	215.0	1300.0	295.0	285.0	335.0	575.0	510.0	765.0	215.0	815.0	1030.0	865.0	355.0	0.0	0.0	0.0	115.0	450.0	0.0	0.0	0.0	0.0	720.0	535.0	500.0	410.0	365.0	630.0	30.0	10.0	125.0	85.0	490.0	285.0	395.0	370.0	480.0	60.0	35.0	1195.0	1460.0	605.0
Human Diseases|Infectious Diseases|Pertussis	19979.0	24386.0	16224.0	14090.0	2194.0	13738.0	20052.0	18701.0	17197.0	17194.0	14086.0	15218.0	16304.0	18279.0	11684.0	12893.0	14322.0	14889.0	10174.0	15937.0	27015.0	9817.0	65916.0	12973.0	8304.0	20007.0	23727.0	8306.0	10231.0	14624.0	10754.0	12469.0	6246.0	9156.0	9609.0	11397.0	8589.0	58739.0	52122.0	40506.0	85432.0	15746.0	43055.0	28886.0	38257.0	72057.0	7771.0	7911.0	7731.0	5614.0	5440.0	14202.0	12477.0	11880.0	6646.0	13200.0	12242.0	6975.0	9940.0	9135.0	12515.0	25523.0	26655.0	21247.0	19221.0	12072.0
Human Diseases|Infectious Diseases|Shigellosis	312.0	450.0	248.0	224.0	2.0	404.0	660.0	628.0	562.0	592.0	244.0	304.0	330.0	318.0	84.0	256.0	254.0	250.0	198.0	536.0	212.0	195.0	529.0	176.0	86.0	522.0	122.0	114.0	134.0	230.0	204.0	306.0	86.0	326.0	412.0	346.0	142.0	7.0	28.0	15.0	106.0	184.0	0.0	2.0	0.0	6.0	288.0	214.0	200.0	164.0	146.0	254.0	16.0	4.0	50.0	40.0	196.0	114.0	158.0	148.0	192.0	28.0	18.0	478.0	584.0	242.0
Human Diseases|Infectious Diseases|Staphylococcus aureus infection	368.0	481.0	3774.0	2580.0	1852.0	6881.0	9038.0	8817.0	8038.0	1295.0	3075.0	1171.0	1266.0	6467.0	7665.0	1651.0	5093.0	5497.0	1801.0	1718.0	3130.0	1101.0	1709.0	799.0	301.0	852.0	385.0	784.0	2150.0	2809.0	4071.0	1439.0	12137.0	2795.0	5176.0	5282.0	1723.0	390.0	182.0	2355.0	1232.0	1346.0	4874.0	3496.0	4803.0	6364.0	2994.0	6038.0	2452.0	5985.0	3407.0	4734.0	3486.0	1365.0	2821.0	2796.0	7044.0	2945.0	6176.0	6978.0	3981.0	24431.0	24527.0	22213.0	16507.0	13514.0
Human Diseases|Infectious Diseases|Toxoplasmosis	0.0	0.0	0.0	0.0	0.0	8.0	4.0	1.0	2.0	0.0	0.0	0.0	0.0	2.0	6.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	2.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2400.0	737.0	0.0	2.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.0	0.0	2.0	0.0	1.0	0.0	1.0	0.0
Human Diseases|Infectious Diseases|Tuberculosis	23741.0	26937.0	21447.0	19379.0	14452.0	22157.0	26014.0	29243.0	25319.0	20490.0	21118.0	22497.0	23003.0	27065.0	20751.0	17397.0	22380.0	25009.0	15451.0	19381.0	24055.0	22457.0	30391.0	27146.0	28704.0	38300.0	27020.0	15645.0	19505.0	26335.0	20261.0	20144.0	37984.0	33740.0	29515.0	29638.0	22139.0	34641.0	27129.0	23101.0	37664.0	17788.0	26131.0	18339.0	19783.0	29255.0	19354.0	17167.0	13460.0	17278.0	12777.0	22650.0	21034.0	16711.0	20632.0	29175.0	21776.0	12485.0	19297.0	19822.0	22630.0	24878.0	23099.0	39616.0	31023.0	31964.0
Human Diseases|Infectious Diseases|Vibrio cholerae infection	0.0	0.0	0.0	0.0	0.0	4.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	3.0	2.0	0.0	0.0	0.0	0.0	0.0	2.0	2.0	22.0	1.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	4.0	27.0	9.0	4.0	3.0	6.0	5.0	7.0	2.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	0.0	2.0	3.0	0.0	0.0	0.0	0.0	0.0	9.0	8.0	11.0	0.0	3.0
Human Diseases|Infectious Diseases|Vibrio cholerae pathogenic cycle	16132.0	18908.0	13567.0	12022.0	8794.0	13476.0	19997.0	21795.0	18871.0	15918.0	12906.0	14291.0	14511.0	17244.0	11121.0	9761.0	10656.0	11135.0	8117.0	11030.0	15474.0	11196.0	38874.0	13813.0	11555.0	22583.0	17808.0	8021.0	9712.0	13827.0	10792.0	12121.0	16632.0	17182.0	15602.0	16939.0	10195.0	29955.0	26345.0	21976.0	44424.0	12334.0	27214.0	19423.0	22872.0	39272.0	12449.0	10782.0	10020.0	9995.0	7892.0	14237.0	12508.0	10715.0	10888.0	15083.0	11969.0	6858.0	10527.0	10748.0	13672.0	19094.0	19783.0	25533.0	19165.0	16913.0
Human Diseases|Metabolic Diseases|Type I diabetes mellitus	11388.0	13073.0	9953.0	9019.0	6068.0	9752.0	12302.0	13196.0	11627.0	9038.0	9858.0	10651.0	10881.0	12239.0	8384.0	9831.0	11746.0	13044.0	8191.0	10815.0	11892.0	10937.0	11714.0	8881.0	8750.0	16365.0	9934.0	7119.0	9421.0	12177.0	9432.0	9092.0	15203.0	14234.0	13115.0	12823.0	9130.0	13722.0	11524.0	9753.0	15088.0	8547.0	9655.0	6697.0	7149.0	10265.0	7690.0	6809.0	5579.0	6675.0	5139.0	10495.0	9598.0	7544.0	7960.0	12419.0	9721.0	5475.0	8352.0	8489.0	10166.0	10010.0	9632.0	16984.0	12153.0	10910.0
Human Diseases|Metabolic Diseases|Type II diabetes mellitus	8426.0	9545.0	7588.0	6816.0	5267.0	9194.0	10016.0	10675.0	9529.0	8426.0	7459.0	7940.0	8229.0	9316.0	6997.0	8003.0	10119.0	11259.0	6796.0	9304.0	11380.0	9071.0	14186.0	7925.0	7320.0	12294.0	8706.0	5496.0	6561.0	8988.0	7039.0	7341.0	13402.0	12217.0	11329.0	11171.0	9239.0	12327.0	11100.0	9537.0	16664.0	6228.0	11419.0	8494.0	9686.0	15278.0	7540.0	6686.0	5474.0	6568.0	5068.0	7680.0	7554.0	5847.0	7876.0	9512.0	7158.0	4159.0	6802.0	6699.0	7860.0	9241.0	8290.0	14167.0	11854.0	10761.0
Human Diseases|Neurodegenerative Diseases|Alzheimer's disease	7175.0	8309.0	6704.0	6039.0	5085.0	7570.0	8836.0	10173.0	8724.0	7332.0	6372.0	6871.0	6890.0	8420.0	6517.0	5992.0	6871.0	7631.0	5117.0	6095.0	7914.0	6686.0	12792.0	8688.0	8996.0	11309.0	9045.0	4995.0	6264.0	8183.0	6500.0	6324.0	11874.0	9256.0	8945.0	9094.0	6494.0	23485.0	13902.0	9166.0	16317.0	5769.0	12022.0	8393.0	9265.0	14251.0	7006.0	6116.0	5352.0	6206.0	4514.0	6834.0	7352.0	5655.0	6092.0	9209.0	6265.0	3613.0	6167.0	6322.0	6829.0	8580.0	8483.0	12479.0	9928.0	9742.0
Human Diseases|Neurodegenerative Diseases|Amyotrophic lateral sclerosis (ALS)	2786.0	3260.0	2238.0	1963.0	483.0	3879.0	5127.0	4717.0	4420.0	3723.0	2362.0	2603.0	2938.0	3209.0	1863.0	4064.0	4762.0	5107.0	3263.0	5127.0	6155.0	3482.0	10290.0	2487.0	1337.0	3402.0	3265.0	1708.0	2281.0	3199.0	2857.0	2311.0	3593.0	3890.0	4640.0	4509.0	3602.0	10063.0	7431.0	4975.0	10235.0	2106.0	6574.0	4756.0	5702.0	9768.0	2692.0	2259.0	2253.0	1830.0	1683.0	2385.0	2400.0	1883.0	3069.0	3246.0	2607.0	1509.0	2880.0	2543.0	2125.0	5074.0	5394.0	5835.0	4356.0	2644.0
Human Diseases|Neurodegenerative Diseases|Huntington's disease	7165.0	8144.0	5579.0	5084.0	3815.0	6475.0	6918.0	7310.0	6436.0	5743.0	5913.0	6299.0	6581.0	7922.0	5169.0	5855.0	6410.0	6693.0	4688.0	6507.0	8292.0	4682.0	16514.0	8239.0	8047.0	10069.0	8726.0	3460.0	4696.0	6366.0	5009.0	4936.0	4236.0	6174.0	5522.0	5582.0	4598.0	24942.0	15305.0	9073.0	18535.0	5155.0	10368.0	7851.0	9034.0	15573.0	4942.0	4709.0	4528.0	4050.0	3167.0	6458.0	4981.0	4386.0	4900.0	5528.0	5635.0	3113.0	5170.0	4498.0	5442.0	8910.0	8237.0	10222.0	8985.0	6740.0
Human Diseases|Neurodegenerative Diseases|Parkinson's disease	6.0	24.0	18.0	48.0	0.0	200.0	9.0	4.0	8.0	3.0	3.0	90.0	9.0	41.0	16.0	0.0	0.0	6.0	10.0	0.0	0.0	0.0	3.0	0.0	0.0	5.0	4.0	0.0	6.0	0.0	0.0	3.0	0.0	0.0	0.0	0.0	3.0	9600.0	2951.0	0.0	7.0	6.0	21.0	9.0	6.0	3.0	42.0	21.0	378.0	48.0	6.0	0.0	3.0	3.0	0.0	3.0	0.0	0.0	4.0	0.0	2.0	0.0	1.0	3.0	7.0	3.0
Human Diseases|Neurodegenerative Diseases|Prion diseases	1367.0	1692.0	1145.0	921.0	408.0	1601.0	2315.0	2158.0	2017.0	1987.0	979.0	1109.0	1231.0	1392.0	648.0	969.0	970.0	936.0	718.0	1320.0	1598.0	988.0	4919.0	1392.0	712.0	2116.0	1589.0	550.0	533.0	865.0	704.0	985.0	1791.0	1916.0	2526.0	2363.0	1031.0	3751.0	2962.0	2305.0	5086.0	1030.0	3262.0	2490.0	2760.0	4827.0	1806.0	1322.0	1343.0	1084.0	952.0	1242.0	703.0	824.0	2356.0	1313.0	831.0	482.0	662.0	686.0	1043.0	1850.0	1842.0	2279.0	2243.0	1220.0
Metabolism|Amino Acid Metabolism|Alanine, aspartate and glutamate metabolism	208193.0	233737.0	173808.0	160053.0	108253.0	147695.0	186635.0	208377.0	181036.0	157470.0	178828.0	195755.0	200243.0	226602.0	165792.0	140155.0	175150.0	194623.0	120911.0	158540.0	200570.0	183570.0	246171.0	183472.0	182641.0	316251.0	205292.0	133050.0	165125.0	221442.0	162804.0	170746.0	272019.0	238166.0	226141.0	226158.0	170444.0	275688.0	239189.0	196743.0	331503.0	153569.0	202945.0	147454.0	162149.0	245708.0	142310.0	119472.0	99313.0	118756.0	89482.0	180718.0	172617.0	141543.0	154239.0	231656.0	172782.0	99376.0	154953.0	150933.0	176863.0	151029.0	149863.0	264969.0	216885.0	207987.0
Metabolism|Amino Acid Metabolism|Amino acid related enzymes	239479.0	270823.0	210215.0	189074.0	140358.0	217950.0	252680.0	282517.0	245447.0	214037.0	205145.0	221888.0	226500.0	261907.0	196106.0	172708.0	214215.0	238116.0	147201.0	193088.0	249625.0	226140.0	354145.0	234152.0	233438.0	365463.0	258140.0	160329.0	195435.0	261279.0	196740.0	201312.0	362608.0	305112.0	290715.0	293790.0	214056.0	377656.0	306778.0	258182.0	443540.0	180223.0	303414.0	221936.0	244432.0	374415.0	206112.0	179824.0	145862.0	180352.0	133166.0	219962.0	204726.0	165161.0	192469.0	295750.0	197549.0	114101.0	179686.0	186218.0	216433.0	221243.0	214677.0	364302.0	295482.0	292931.0
Metabolism|Amino Acid Metabolism|Arginine and proline metabolism	204333.0	229462.0	166020.0	156508.0	130357.0	153589.0	190044.0	219961.0	187444.0	152586.0	171981.0	188906.0	192315.0	221312.0	164796.0	133598.0	163780.0	180892.0	117272.0	152185.0	208747.0	181738.0	319111.0	212514.0	217418.0	321257.0	235452.0	133728.0	165091.0	222126.0	161416.0	160593.0	283180.0	243833.0	231435.0	234400.0	181751.0	314772.0	278099.0	225165.0	395147.0	150314.0	244192.0	176628.0	200033.0	314941.0	135542.0	111314.0	94774.0	110040.0	85577.0	178967.0	184146.0	145689.0	155546.0	241075.0	167243.0	96182.0	155823.0	150496.0	174704.0	191561.0	194729.0	280961.0	213676.0	212657.0
Metabolism|Amino Acid Metabolism|Cysteine and methionine metabolism	162427.0	183359.0	138662.0	126084.0	98936.0	157219.0	182778.0	204344.0	177392.0	156604.0	138092.0	147391.0	151150.0	176157.0	133788.0	116896.0	144032.0	159066.0	98643.0	131344.0	182668.0	153666.0	284850.0	162391.0	155366.0	246876.0	183842.0	103795.0	127558.0	170155.0	131502.0	138186.0	243346.0	203772.0	195890.0	197892.0	149841.0	262806.0	226240.0	197283.0	348286.0	124246.0	241929.0	175699.0	196170.0	306910.0	151463.0	129139.0	104959.0	129329.0	95869.0	148386.0	143161.0	115576.0	134159.0	192538.0	130350.0	76062.0	120249.0	123528.0	148367.0	163965.0	162550.0	261914.0	208806.0	209329.0
Metabolism|Amino Acid Metabolism|Glycine, serine and threonine metabolism	147609.0	169446.0	124172.0	114148.0	83672.0	133173.0	164127.0	181853.0	158137.0	140194.0	133197.0	142272.0	146746.0	168969.0	124228.0	108624.0	130423.0	143198.0	90911.0	121362.0	163845.0	134640.0	255512.0	156095.0	152522.0	233951.0	171810.0	96295.0	119548.0	160156.0	121894.0	129473.0	205448.0	171855.0	166856.0	171746.0	132307.0	241685.0	208342.0	175858.0	321183.0	117495.0	211155.0	150119.0	169473.0	264306.0	128653.0	110810.0	91636.0	108726.0	81199.0	131116.0	130753.0	106175.0	110537.0	170441.0	125209.0	72152.0	109127.0	111983.0	135310.0	141929.0	138039.0	219707.0	185191.0	176740.0
Metabolism|Amino Acid Metabolism|Histidine metabolism	105695.0	117997.0	83641.0	79841.0	57935.0	70277.0	92618.0	105768.0	90758.0	75294.0	91439.0	102173.0	105016.0	121243.0	93657.0	76083.0	97767.0	107911.0	66146.0	87237.0	118247.0	96613.0	137410.0	103142.0	103911.0	171424.0	117579.0	71932.0	89285.0	120131.0	88784.0	85757.0	151613.0	122331.0	121245.0	119438.0	103524.0	137420.0	126766.0	104360.0	180232.0	75934.0	107754.0	77653.0	88443.0	138345.0	66121.0	58259.0	47235.0	58523.0	42685.0	92944.0	90216.0	72927.0	87973.0	127073.0	92047.0	52359.0	81539.0	80507.0	93317.0	92634.0	97771.0	152832.0	123554.0	117451.0
Metabolism|Amino Acid Metabolism|Lysine biosynthesis	125941.0	144213.0	108037.0	99845.0	78076.0	118966.0	142649.0	161989.0	139719.0	122999.0	112820.0	123755.0	126200.0	146402.0	109687.0	88469.0	109170.0	120753.0	76230.0	98654.0	130454.0	127709.0	184538.0	129282.0	127925.0	208821.0	139834.0	88501.0	106128.0	146389.0	108215.0	113000.0	218038.0	177026.0	173694.0	175612.0	124909.0	195081.0	157281.0	134267.0	229792.0	98544.0	159888.0	115669.0	125601.0	190757.0	115228.0	97040.0	78424.0	95368.0	70880.0	119473.0	114582.0	93698.0	116006.0	166889.0	107042.0	62277.0	97133.0	99425.0	120953.0	114534.0	113932.0	203831.0	168002.0	166730.0
Metabolism|Amino Acid Metabolism|Lysine degradation	24563.0	28862.0	20539.0	18329.0	12407.0	24997.0	31054.0	32004.0	28505.0	24434.0	19702.0	20012.0	21305.0	25331.0	17676.0	18152.0	20043.0	21197.0	14267.0	21321.0	34781.0	18369.0	87888.0	32147.0	29565.0	34334.0	39289.0	13054.0	15316.0	21332.0	16560.0	16984.0	26163.0	23116.0	24867.0	26289.0	19230.0	81882.0	66017.0	50818.0	103470.0	19655.0	59255.0	41709.0	52393.0	95825.0	16979.0	15970.0	14269.0	14832.0	12203.0	20481.0	19391.0	15668.0	16271.0	25711.0	17617.0	10030.0	16690.0	15860.0	19191.0	41700.0	43638.0	43470.0	30724.0	26967.0
Metabolism|Amino Acid Metabolism|Phenylalanine metabolism	31218.0	34997.0	24078.0	23257.0	16964.0	22299.0	30561.0	33782.0	29303.0	20290.0	30490.0	33966.0	34822.0	39172.0	28639.0	19240.0	23244.0	25442.0	17048.0	22316.0	35502.0	25267.0	68095.0	40222.0	39772.0	56397.0	45641.0	19931.0	23605.0	32424.0	23968.0	25781.0	43554.0	34289.0	34304.0	34389.0	25654.0	66643.0	57430.0	45857.0	89632.0	28502.0	48776.0	35091.0	43106.0	70175.0	15613.0	13078.0	12339.0	12968.0	10716.0	26202.0	28590.0	23996.0	24228.0	39995.0	30251.0	17210.0	27921.0	26434.0	30639.0	43858.0	47448.0	48814.0	30866.0	27504.0
Metabolism|Amino Acid Metabolism|Phenylalanine, tyrosine and tryptophan biosynthesis	137956.0	155881.0	111452.0	103249.0	79394.0	128988.0	152610.0	168681.0	147952.0	133121.0	119475.0	129738.0	132791.0	147691.0	107257.0	96762.0	110532.0	121747.0	80325.0	103161.0	133477.0	127270.0	194730.0	136751.0	138024.0	213632.0	146643.0	94036.0	112840.0	153634.0	112792.0	119431.0	212366.0	175181.0	169956.0	174826.0	125266.0	183753.0	162000.0	143606.0	248152.0	102881.0	176542.0	128723.0	138276.0	207100.0	131973.0	112136.0	90602.0	110548.0	80548.0	119457.0	117849.0	97711.0	114319.0	170297.0	111537.0	65807.0	100316.0	104797.0	127653.0	105853.0	102888.0	195005.0	163579.0	172160.0
Metabolism|Amino Acid Metabolism|Tryptophan metabolism	22387.0	28093.0	20870.0	18272.0	9427.0	33316.0	43985.0	45197.0	40049.0	32556.0	21326.0	21700.0	23197.0	29004.0	20614.0	18899.0	21115.0	22067.0	15433.0	21865.0	34409.0	19811.0	88166.0	33939.0	31698.0	34446.0	38651.0	14148.0	17416.0	24061.0	21377.0	19986.0	34573.0	27369.0	29275.0	32265.0	19055.0	78959.0	61162.0	49171.0	99849.0	21056.0	64549.0	44488.0	55172.0	95839.0	22235.0	20993.0	17963.0	18989.0	15580.0	21349.0	22449.0	17800.0	16978.0	28519.0	21209.0	12026.0	20055.0	20880.0	23015.0	53410.0	54947.0	60668.0	43540.0	35042.0
Metabolism|Amino Acid Metabolism|Tyrosine metabolism	62791.0	71786.0	53146.0	48378.0	36962.0	53308.0	66320.0	76075.0	64757.0	54667.0	49455.0	53562.0	54005.0	69686.0	56180.0	45037.0	56079.0	61801.0	39767.0	49296.0	76242.0	58128.0	117665.0	64675.0	61899.0	91084.0	73460.0	38317.0	48357.0	64064.0	50387.0	49046.0	93111.0	77380.0	71297.0	71685.0	53124.0	113370.0	98419.0	85103.0	152794.0	48112.0	98933.0	68649.0	80379.0	132893.0	46218.0	41869.0	34496.0	43088.0	32139.0	58177.0	56293.0	44303.0	47915.0	69181.0	52811.0	30059.0	50965.0	51665.0	52237.0	80271.0	81129.0	101462.0	83980.0	78017.0
Metabolism|Amino Acid Metabolism|Valine, leucine and isoleucine biosynthesis	123542.0	141326.0	101781.0	92767.0	78079.0	127204.0	149534.0	166161.0	144875.0	126889.0	106074.0	112170.0	114424.0	129348.0	94783.0	87680.0	96709.0	106073.0	71219.0	89466.0	117725.0	114975.0	188985.0	132941.0	134998.0	189148.0	137065.0	80486.0	97454.0	130551.0	99123.0	107265.0	196320.0	160276.0	152998.0	157736.0	107098.0	188506.0	153221.0	135607.0	234132.0	94298.0	173478.0	125174.0	134381.0	204821.0	126437.0	109165.0	85201.0	107484.0	78200.0	114850.0	111661.0	88471.0	100199.0	150389.0	97129.0	56783.0	83527.0	92904.0	115352.0	109757.0	102803.0	191487.0	150533.0	158810.0
Metabolism|Amino Acid Metabolism|Valine, leucine and isoleucine degradation	40504.0	47403.0	34181.0	31052.0	21558.0	39875.0	45090.0	48826.0	42553.0	35898.0	34472.0	35171.0	37458.0	48570.0	37714.0	36401.0	44744.0	48512.0	30242.0	41196.0	57816.0	37339.0	87822.0	44607.0	42568.0	55488.0	49077.0	25040.0	32732.0	42972.0	35535.0	31676.0	47052.0	44928.0	39969.0	40544.0	35978.0	90282.0	72258.0	55329.0	101354.0	30453.0	63147.0	46013.0	54554.0	90756.0	29152.0	27541.0	22270.0	26532.0	20657.0	36305.0	36888.0	27850.0	24547.0	43245.0	35234.0	19444.0	33386.0	32453.0	34456.0	59775.0	59235.0	73742.0	64500.0	55843.0
Metabolism|Biosynthesis of Other Secondary Metabolites|Betalain biosynthesis	0.0	0.0	0.0	0.0	0.0	10.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Metabolism|Biosynthesis of Other Secondary Metabolites|Butirosin and neomycin biosynthesis	6881.0	7703.0	6876.0	7028.0	7877.0	8524.0	10787.0	12360.0	10709.0	9741.0	8281.0	9160.0	9277.0	10459.0	9013.0	5851.0	8129.0	9283.0	5755.0	7222.0	9538.0	9021.0	13003.0	13503.0	13770.0	17668.0	12553.0	6050.0	7598.0	11084.0	8658.0	8973.0	16305.0	11985.0	11972.0	11620.0	10689.0	11071.0	10991.0	8939.0	13917.0	6042.0	12111.0	8702.0	9744.0	13981.0	9413.0	7689.0	6032.0	8127.0	5626.0	7578.0	10985.0	7175.0	9186.0	11098.0	8383.0	4992.0	9304.0	7416.0	7436.0	7152.0	6566.0	14047.0	12008.0	13044.0
Metabolism|Biosynthesis of Other Secondary Metabolites|Caffeine metabolism	1.0	1.0	0.0	0.0	1.0	0.0	0.0	0.0	1.0	0.0	2.0	0.0	0.0	0.0	2.0	0.0	1.0	1.0	0.0	0.0	0.0	0.0	0.0	1516.0	2140.0	245.0	779.0	0.0	0.0	0.0	0.0	3.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.0	1.0	0.0	0.0	2.0	1.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	1.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Metabolism|Biosynthesis of Other Secondary Metabolites|Clavulanic acid biosynthesis	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Metabolism|Biosynthesis of Other Secondary Metabolites|Flavone and flavonol biosynthesis	278.0	431.0	351.0	543.0	8.0	1119.0	378.0	339.0	313.0	331.0	943.0	1341.0	1548.0	561.0	397.0	1002.0	1288.0	1476.0	685.0	1227.0	1532.0	1881.0	1043.0	831.0	536.0	1660.0	922.0	393.0	296.0	473.0	407.0	379.0	1268.0	2667.0	1879.0	1409.0	246.0	612.0	305.0	759.0	377.0	750.0	18.0	9.0	14.0	24.0	189.0	163.0	136.0	219.0	330.0	1942.0	20.0	35.0	1050.0	2230.0	132.0	79.0	213.0	404.0	608.0	965.0	258.0	563.0	333.0	417.0
Metabolism|Biosynthesis of Other Secondary Metabolites|Flavonoid biosynthesis	237.0	131.0	99.0	96.0	901.0	209.0	68.0	12.0	107.0	1.0	4.0	5.0	4.0	33.0	131.0	3.0	2.0	4.0	1.0	0.0	0.0	223.0	100.0	1877.0	2358.0	768.0	1208.0	58.0	28.0	24.0	11.0	34.0	1135.0	2239.0	1286.0	959.0	491.0	465.0	159.0	49.0	10.0	8.0	19.0	8.0	16.0	0.0	28.0	143.0	186.0	551.0	334.0	137.0	194.0	38.0	1328.0	138.0	414.0	256.0	398.0	468.0	100.0	4.0	0.0	4.0	77.0	19.0
Metabolism|Biosynthesis of Other Secondary Metabolites|Indole alkaloid biosynthesis	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Metabolism|Biosynthesis of Other Secondary Metabolites|Isoflavonoid biosynthesis	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Metabolism|Biosynthesis of Other Secondary Metabolites|Isoquinoline alkaloid biosynthesis	11136.0	12350.0	8726.0	8044.0	4829.0	7376.0	9299.0	9616.0	8593.0	8094.0	9286.0	10240.0	10527.0	11212.0	7810.0	7028.0	8710.0	9635.0	5997.0	8578.0	11876.0	9172.0	20041.0	11056.0	11370.0	16477.0	12936.0	6789.0	8368.0	10964.0	8159.0	8701.0	10466.0	10147.0	9230.0	9877.0	9099.0	19493.0	16882.0	13080.0	24049.0	8309.0	13405.0	10176.0	12028.0	19546.0	7101.0	5854.0	5552.0	6059.0	4723.0	8475.0	8273.0	7091.0	5937.0	11309.0	8928.0	5517.0	9998.0	8833.0	10107.0	8681.0	10097.0	13122.0	8817.0	9153.0
Metabolism|Biosynthesis of Other Secondary Metabolites|Novobiocin biosynthesis	23004.0	26351.0	18728.0	17189.0	12763.0	22384.0	27034.0	29008.0	25612.0	23154.0	20130.0	22006.0	22622.0	25131.0	18212.0	15387.0	18015.0	19612.0	13131.0	17216.0	23036.0	21120.0	39047.0	21974.0	21484.0	35219.0	24865.0	15464.0	18745.0	25125.0	19684.0	19795.0	32362.0	27480.0	26550.0	27922.0	20222.0	33285.0	28678.0	24987.0	44163.0	17204.0	30685.0	23274.0	25533.0	39529.0	21713.0	17480.0	15268.0	17039.0	13320.0	20301.0	18753.0	15540.0	17375.0	27387.0	18753.0	11299.0	19794.0	18982.0	22085.0	22264.0	23582.0	38583.0	29618.0	28341.0
Metabolism|Biosynthesis of Other Secondary Metabolites|Penicillin and cephalosporin biosynthesis	11819.0	12768.0	9625.0	8143.0	1498.0	3269.0	3154.0	3966.0	3107.0	2222.0	6723.0	7043.0	7041.0	8115.0	5028.0	3813.0	5365.0	6080.0	3768.0	4566.0	4300.0	2752.0	4697.0	8751.0	10508.0	10714.0	7831.0	3816.0	5604.0	7932.0	5397.0	4935.0	2462.0	2973.0	2215.0	2154.0	3054.0	7014.0	7140.0	5509.0	7731.0	5123.0	3600.0	2736.0	3420.0	2537.0	1852.0	2932.0	1511.0	2556.0	1668.0	7737.0	5918.0	5559.0	2855.0	5305.0	6143.0	3410.0	4094.0	4713.0	6915.0	4366.0	3512.0	3557.0	4576.0	3591.0
Metabolism|Biosynthesis of Other Secondary Metabolites|Phenylpropanoid biosynthesis	18884.0	22629.0	17628.0	19686.0	13864.0	17687.0	23797.0	32946.0	25482.0	21401.0	24142.0	31576.0	31926.0	28556.0	24812.0	25784.0	32324.0	36882.0	23662.0	28791.0	43892.0	44009.0	42418.0	29915.0	25173.0	58499.0	37588.0	18579.0	20223.0	30979.0	20924.0	22139.0	57667.0	62263.0	51941.0	45642.0	27679.0	46552.0	38131.0	35541.0	52573.0	22781.0	37683.0	25496.0	28719.0	44842.0	18691.0	14748.0	11685.0	14989.0	11433.0	27113.0	28288.0	19796.0	33120.0	45233.0	17535.0	10504.0	17647.0	17234.0	20042.0	18259.0	16165.0	27080.0	26480.0	30645.0
Metabolism|Biosynthesis of Other Secondary Metabolites|Stilbenoid, diarylheptanoid and gingerol biosynthesis	98.0	18.0	22.0	7.0	91.0	59.0	26.0	18.0	70.0	99.0	27.0	23.0	8.0	40.0	158.0	629.0	391.0	397.0	312.0	282.0	4.0	154.0	89.0	308.0	186.0	462.0	179.0	54.0	2.0	2.0	4.0	46.0	1139.0	1562.0	1105.0	797.0	455.0	466.0	159.0	51.0	15.0	13.0	55.0	18.0	35.0	10.0	36.0	147.0	150.0	380.0	236.0	26.0	11.0	10.0	1320.0	99.0	852.0	513.0	802.0	946.0	117.0	247.0	203.0	29.0	82.0	68.0
Metabolism|Biosynthesis of Other Secondary Metabolites|Streptomycin biosynthesis	62887.0	70448.0	52721.0	48590.0	31219.0	40351.0	48898.0	55065.0	47796.0	42340.0	55771.0	61025.0	62702.0	71212.0	54427.0	48331.0	64385.0	72513.0	43164.0	56826.0	70953.0	57430.0	59822.0	59879.0	62336.0	96945.0	63176.0	38934.0	50316.0	66858.0	50805.0	53676.0	74978.0	68865.0	60035.0	57996.0	56963.0	67842.0	65131.0	54429.0	88776.0	46990.0	52709.0	37134.0	40302.0	56232.0	41081.0	36122.0	28279.0	37052.0	26316.0	51945.0	53614.0	43264.0	42064.0	63885.0	55391.0	32084.0	52164.0	47770.0	54821.0	41982.0	38967.0	67759.0	63479.0	62105.0
Metabolism|Biosynthesis of Other Secondary Metabolites|Tropane, piperidine and pyridine alkaloid biosynthesis	19696.0	22531.0	16029.0	14835.0	12138.0	17375.0	21735.0	22399.0	20124.0	17402.0	17424.0	19269.0	19801.0	21753.0	15978.0	13088.0	15983.0	17402.0	11044.0	15433.0	21178.0	17469.0	37097.0	20554.0	19911.0	32701.0	23515.0	13250.0	16361.0	21228.0	16657.0	16463.0	24988.0	21955.0	21600.0	22122.0	17213.0	31716.0	27426.0	22660.0	40826.0	14828.0	25493.0	19466.0	22646.0	36120.0	14683.0	11988.0	10955.0	11943.0	9545.0	16850.0	15663.0	12795.0	14731.0	23448.0	16484.0	9699.0	17378.0	16374.0	18374.0	22140.0	24431.0	34409.0	24403.0	23434.0
Metabolism|Biosynthesis of Other Secondary Metabolites|beta-Lactam resistance	8665.0	9376.0	7495.0	6065.0	768.0	3255.0	2547.0	2876.0	2388.0	1928.0	4758.0	4627.0	4825.0	5700.0	3700.0	3557.0	5322.0	6014.0	3266.0	4520.0	4275.0	3814.0	3975.0	5967.0	7546.0	8204.0	5555.0	3820.0	4721.0	7008.0	4451.0	3307.0	4563.0	4724.0	3956.0	4633.0	4006.0	4734.0	4850.0	3797.0	4638.0	3107.0	2959.0	2091.0	2729.0	1798.0	1360.0	2041.0	1154.0	1709.0	1544.0	5378.0	3803.0	3789.0	2803.0	5517.0	4222.0	2356.0	3368.0	3732.0	5029.0	4219.0	3657.0	3727.0	4466.0	4366.0
Metabolism|Carbohydrate Metabolism|Amino sugar and nucleotide sugar metabolism	268702.0	301563.0	239704.0	229920.0	158876.0	210899.0	256807.0	340314.0	273840.0	215232.0	246493.0	268111.0	272451.0	322878.0	246768.0	200743.0	259106.0	288909.0	181312.0	230392.0	297635.0	241494.0	385683.0	278632.0	264897.0	453097.0	307989.0	169879.0	215342.0	287773.0	217065.0	230954.0	383781.0	309567.0	307890.0	299291.0	263398.0	396823.0	354784.0	292601.0	520045.0	207555.0	330091.0	242493.0	267262.0	420423.0	210388.0	185431.0	145149.0	184321.0	133213.0	238751.0	253836.0	199682.0	215127.0	298633.0	241922.0	138096.0	229013.0	210760.0	242951.0	266596.0	254176.0	383819.0	323880.0	315603.0
Metabolism|Carbohydrate Metabolism|Ascorbate and aldarate metabolism	23165.0	29080.0	19737.0	19629.0	11867.0	29940.0	35039.0	46697.0	36788.0	30262.0	21487.0	22685.0	22881.0	31480.0	26772.0	11555.0	13107.0	13402.0	12164.0	13183.0	29004.0	14252.0	74273.0	30861.0	25046.0	38724.0	36767.0	14707.0	18478.0	24460.0	21800.0	22327.0	36136.0	22179.0	23738.0	26167.0	19816.0	68969.0	57958.0	48401.0	97392.0	20636.0	67645.0	46669.0	56138.0	92744.0	22781.0	18069.0	14854.0	17602.0	14695.0	22186.0	29995.0	22804.0	20614.0	31335.0	19745.0	11468.0	20376.0	19528.0	22882.0	46856.0	45634.0	50294.0	43412.0	37162.0
Metabolism|Carbohydrate Metabolism|Butanoate metabolism	99393.0	116720.0	86935.0	78128.0	62973.0	101882.0	135167.0	146424.0	128095.0	99515.0	86965.0	92256.0	94644.0	117371.0	85576.0	73842.0	85683.0	92673.0	62433.0	80969.0	115010.0	92835.0	235708.0	111030.0	102637.0	154840.0	126812.0	60110.0	73079.0	100916.0	81059.0	81006.0	152852.0	126032.0	126320.0	128845.0	84201.0	206183.0	168965.0	142317.0	266220.0	82269.0	172117.0	124337.0	148120.0	246723.0	80576.0	73717.0	60168.0	71197.0	54762.0	99813.0	90551.0	71319.0	79873.0	125039.0	90334.0	51418.0	85965.0	87809.0	97887.0	156207.0	162924.0	203698.0	144965.0	132438.0
Metabolism|Carbohydrate Metabolism|C5-Branched dibasic acid metabolism	53561.0	62218.0	44079.0	40600.0	31122.0	59397.0	71744.0	78448.0	68849.0	63279.0	47872.0	50343.0	51832.0	56417.0	40733.0	43158.0	47423.0	51815.0	33994.0	45250.0	59865.0	53728.0	96024.0	56700.0	53912.0	83068.0	60840.0	35166.0	42247.0	56723.0	44015.0	49200.0	86476.0	70948.0	68604.0	70605.0	50638.0	91901.0	74130.0	65994.0	117360.0	42894.0	88007.0	63126.0	68728.0	105744.0	61848.0	51510.0	41950.0	50890.0	37570.0	48403.0	47968.0	38795.0	42573.0	65569.0	41906.0	25182.0	37052.0	40676.0	50584.0	46739.0	44120.0	83992.0	69586.0	72010.0
Metabolism|Carbohydrate Metabolism|Citrate cycle (TCA cycle)	119389.0	138583.0	99412.0	91127.0	63319.0	96385.0	127914.0	132819.0	119006.0	90969.0	104934.0	112932.0	117472.0	135960.0	95160.0	102029.0	119675.0	130610.0	84971.0	112411.0	136857.0	96557.0	179822.0	119076.0	120865.0	173101.0	130017.0	72758.0	96740.0	125261.0	98832.0	93408.0	129083.0	108801.0	108558.0	111380.0	96072.0	203785.0	166088.0	126984.0	230175.0	89518.0	141092.0	99255.0	113731.0	173015.0	73851.0	63946.0	57577.0	61125.0	48803.0	101490.0	102854.0	81741.0	67932.0	122207.0	105638.0	59511.0	97882.0	94004.0	104339.0	133196.0	138118.0	181716.0	135260.0	105842.0
Metabolism|Carbohydrate Metabolism|Fructose and mannose metabolism	150689.0	169506.0	135770.0	140762.0	108548.0	95392.0	118961.0	214762.0	153993.0	92174.0	128822.0	145293.0	146907.0	194683.0	156500.0	100403.0	133376.0	146378.0	96278.0	114180.0	159141.0	132104.0	243845.0	176603.0	164169.0	271974.0	194810.0	90961.0	116861.0	164803.0	120350.0	114152.0	235155.0	190433.0	196472.0	182589.0	154752.0	252505.0	224091.0	173657.0	315616.0	111820.0	183929.0	135364.0	154515.0	252022.0	80485.0	74727.0	58853.0	74118.0	53808.0	141607.0	152495.0	118011.0	127339.0	182426.0	136126.0	74237.0	136168.0	114682.0	125101.0	195505.0	194676.0	220949.0	203051.0	203191.0
Metabolism|Carbohydrate Metabolism|Galactose metabolism	168027.0	191176.0	154312.0	143781.0	81091.0	124577.0	150703.0	187211.0	153522.0	134689.0	151229.0	165192.0	169028.0	197395.0	155172.0	105999.0	146876.0	164349.0	100704.0	125286.0	164780.0	136776.0	192230.0	148891.0	138693.0	266333.0	166359.0	100758.0	129139.0	181835.0	135353.0	142585.0	213724.0	176770.0	166659.0	163585.0	134235.0	200678.0	184556.0	164919.0	274334.0	125804.0	177851.0	124967.0	136190.0	205849.0	123812.0	107452.0	80260.0	106658.0	77106.0	152419.0	150038.0	123440.0	127483.0	186947.0	142469.0	81455.0	127491.0	117806.0	141197.0	144626.0	128990.0	217965.0	216634.0	208533.0
Metabolism|Carbohydrate Metabolism|Glycolysis / Gluconeogenesis	198269.0	228484.0	183771.0	166077.0	125095.0	184933.0	223847.0	267829.0	224704.0	185008.0	169978.0	181057.0	183258.0	232419.0	182980.0	127653.0	160527.0	176829.0	115561.0	138366.0	192554.0	159661.0	320318.0	208715.0	198033.0	311639.0	225006.0	122630.0	153204.0	208559.0	162288.0	166546.0	311106.0	231205.0	234976.0	235316.0	170490.0	336514.0	280406.0	237801.0	424348.0	149836.0	293233.0	206880.0	230969.0	367285.0	171615.0	150080.0	118270.0	147780.0	109454.0	179182.0	190846.0	149468.0	174859.0	224641.0	173382.0	98294.0	160553.0	160049.0	178012.0	237633.0	229031.0	327229.0	281815.0	264438.0
Metabolism|Carbohydrate Metabolism|Glyoxylate and dicarboxylate metabolism	86500.0	100492.0	71830.0	68202.0	47826.0	73741.0	92061.0	107028.0	90472.0	72872.0	81002.0	88877.0	91799.0	104177.0	72160.0	66655.0	81017.0	88454.0	56813.0	80060.0	104995.0	81506.0	170687.0	98985.0	98192.0	144930.0	112909.0	55119.0	65953.0	91087.0	67124.0	72366.0	112824.0	107348.0	104717.0	103745.0	80965.0	154148.0	135162.0	108252.0	207168.0	72050.0	118200.0	85156.0	100485.0	163590.0	55919.0	48067.0	42500.0	44910.0	36487.0	81774.0	76282.0	62810.0	64661.0	103154.0	78079.0	45045.0	70068.0	67856.0	82804.0	93145.0	94391.0	128572.0	102655.0	90737.0
Metabolism|Carbohydrate Metabolism|Inositol phosphate metabolism	20182.0	22077.0	16405.0	14649.0	11957.0	15869.0	17272.0	19581.0	17059.0	14820.0	17297.0	18838.0	19426.0	22877.0	17529.0	11027.0	14010.0	15382.0	10123.0	12274.0	17759.0	14252.0	23380.0	21072.0	21289.0	30831.0	21801.0	12168.0	16300.0	19758.0	16213.0	16698.0	21198.0	18880.0	16602.0	16443.0	11768.0	31091.0	23941.0	19327.0	33910.0	15717.0	24510.0	19455.0	17963.0	24841.0	20373.0	15292.0	12867.0	15153.0	11307.0	15968.0	16782.0	14265.0	11510.0	20649.0	16845.0	9582.0	15415.0	15540.0	17055.0	17844.0	15338.0	24201.0	24036.0	22641.0
Metabolism|Carbohydrate Metabolism|Pentose and glucuronate interconversions	98677.0	108200.0	75213.0	74943.0	61445.0	47968.0	56303.0	81488.0	62637.0	42740.0	85013.0	95097.0	97407.0	114321.0	88722.0	52486.0	65826.0	72181.0	52173.0	60142.0	98609.0	76598.0	168477.0	102057.0	97358.0	163833.0	126558.0	55417.0	70011.0	96513.0	67969.0	71305.0	104996.0	104237.0	94540.0	89577.0	65397.0	174793.0	154963.0	123036.0	229415.0	79346.0	112927.0	79469.0	96110.0	164362.0	30268.0	26522.0	21781.0	25957.0	22268.0	93150.0	88370.0	72208.0	71435.0	113405.0	82229.0	46387.0	78020.0	65780.0	76747.0	103151.0	98877.0	96974.0	87615.0	78068.0
Metabolism|Carbohydrate Metabolism|Pentose phosphate pathway	141918.0	160772.0	123656.0	117196.0	92726.0	121419.0	141126.0	181896.0	148177.0	116122.0	125538.0	137366.0	139306.0	172098.0	134486.0	94051.0	119796.0	131249.0	84851.0	105345.0	152289.0	130052.0	241275.0	159507.0	153031.0	243267.0	178617.0	90480.0	109148.0	151964.0	112036.0	117030.0	221301.0	187776.0	180834.0	179217.0	128492.0	245557.0	210097.0	174582.0	316368.0	112098.0	192821.0	140024.0	159391.0	263364.0	103279.0	90074.0	72954.0	88214.0	67366.0	134220.0	131834.0	106923.0	122084.0	177146.0	125799.0	70600.0	112899.0	108863.0	124956.0	165744.0	158376.0	221582.0	196214.0	183398.0
Metabolism|Carbohydrate Metabolism|Propanoate metabolism	77734.0	91456.0	68691.0	62643.0	47787.0	87593.0	107188.0	116766.0	102025.0	83818.0	76721.0	80273.0	83152.0	101920.0	74335.0	69222.0	85614.0	92913.0	57670.0	80591.0	104169.0	79488.0	164839.0	86658.0	82269.0	125227.0	95346.0	49767.0	59841.0	82668.0	66703.0	71136.0	125443.0	102078.0	105408.0	106017.0	82663.0	142900.0	118901.0	99996.0	189050.0	65587.0	123393.0	91076.0	105425.0	170744.0	71982.0	65372.0	53471.0	61756.0	47251.0	77168.0	71105.0	57069.0	67130.0	100124.0	77201.0	43625.0	70661.0	69982.0	77234.0	115475.0	114451.0	161091.0	128734.0	111408.0
Metabolism|Carbohydrate Metabolism|Pyruvate metabolism	177634.0	200500.0	150927.0	138262.0	120819.0	152707.0	182449.0	205275.0	177088.0	143958.0	156729.0	168063.0	171963.0	212516.0	160139.0	134466.0	166792.0	181962.0	117356.0	150584.0	197140.0	156895.0	284543.0	179600.0	179363.0	274883.0	199332.0	112431.0	139148.0	188926.0	142322.0	142149.0	242238.0	206766.0	199628.0	201856.0	160668.0	273994.0	235416.0	191113.0	345240.0	131940.0	222583.0	162673.0	182407.0	284553.0	131348.0	120185.0	96305.0	116527.0	86836.0	166020.0	162475.0	129245.0	140488.0	206891.0	162037.0	91059.0	147899.0	143040.0	157067.0	207080.0	199914.0	278256.0	238697.0	217142.0
Metabolism|Carbohydrate Metabolism|Starch and sucrose metabolism	156811.0	180420.0	146902.0	141299.0	104225.0	148031.0	177336.0	212604.0	177831.0	160003.0	159494.0	182070.0	184287.0	203458.0	163914.0	124989.0	161918.0	182653.0	114991.0	143946.0	212226.0	184024.0	300938.0	183291.0	166545.0	311092.0	216984.0	110137.0	130620.0	190527.0	137598.0	154466.0	280498.0	250816.0	225135.0	220110.0	159766.0	297118.0	261105.0	232310.0	402891.0	145027.0	266614.0	187100.0	211243.0	342492.0	149316.0	122283.0	97850.0	123005.0	91893.0	165247.0	172157.0	133197.0	155633.0	228963.0	140750.0	82563.0	138402.0	126508.0	151391.0	170444.0	158950.0	239403.0	210495.0	220199.0
Metabolism|Energy Metabolism|Carbon fixation in photosynthetic organisms	112889.0	125278.0	95022.0	88027.0	64457.0	83095.0	102647.0	123621.0	103785.0	82254.0	93811.0	103102.0	104977.0	122909.0	91528.0	73823.0	92521.0	102216.0	65084.0	83422.0	110651.0	95058.0	158925.0	109244.0	105155.0	175553.0	123399.0	70067.0	86535.0	117168.0	86196.0	87243.0	151040.0	132407.0	124776.0	124200.0	93979.0	178791.0	148663.0	117998.0	208839.0	81833.0	129206.0	95514.0	106623.0	166853.0	77245.0	66947.0	56257.0	67003.0	50271.0	97850.0	96308.0	78800.0	84135.0	129367.0	92181.0	52378.0	84527.0	81478.0	93889.0	104145.0	103665.0	152526.0	125097.0	123268.0
Metabolism|Energy Metabolism|Carbon fixation pathways in prokaryotes	168700.0	191934.0	143066.0	130626.0	91714.0	139052.0	179174.0	186414.0	167049.0	130126.0	156524.0	169369.0	175181.0	196929.0	138668.0	135128.0	166512.0	183683.0	113122.0	156090.0	194553.0	154004.0	275523.0	172839.0	173321.0	269392.0	195322.0	109504.0	137262.0	183514.0	139451.0	139294.0	221463.0	186035.0	185975.0	189931.0	153910.0	272275.0	232652.0	187258.0	341359.0	133601.0	200054.0	145274.0	168330.0	267125.0	112446.0	101258.0	86543.0	97864.0	74807.0	150332.0	140883.0	115281.0	119809.0	200613.0	155015.0	88368.0	144705.0	139311.0	158668.0	190407.0	199055.0	274099.0	188393.0	165458.0
Metabolism|Energy Metabolism|Methane metabolism	183543.0	207035.0	160686.0	148377.0	122419.0	147280.0	187429.0	221666.0	187140.0	142067.0	156026.0	174524.0	177266.0	207922.0	155463.0	124650.0	156563.0	173551.0	110528.0	141868.0	189287.0	179815.0	292723.0	183147.0	177917.0	303821.0	214793.0	125254.0	151937.0	207738.0	150865.0	145264.0	299258.0	248305.0	247125.0	251773.0	173814.0	282369.0	247860.0	206112.0	364056.0	138891.0	230327.0	165197.0	185442.0	297662.0	132144.0	118472.0	94724.0	115887.0	85292.0	169843.0	170556.0	134849.0	160582.0	242169.0	157632.0	89818.0	145129.0	143656.0	164670.0	198783.0	201111.0	286368.0	211027.0	207484.0
Metabolism|Energy Metabolism|Nitrogen metabolism	142528.0	159018.0	116791.0	106856.0	69582.0	113693.0	148847.0	159491.0	140509.0	110607.0	121161.0	132266.0	136131.0	152936.0	109638.0	98837.0	118525.0	129357.0	83082.0	112508.0	142524.0	116473.0	223246.0	125826.0	118297.0	210904.0	147450.0	85319.0	104735.0	142009.0	106466.0	109664.0	180817.0	153012.0	153799.0	155152.0	108720.0	210721.0	184908.0	152126.0	272064.0	104261.0	170139.0	128842.0	146372.0	227425.0	101863.0	84774.0	72568.0	81941.0	63675.0	119614.0	114948.0	94212.0	101175.0	155971.0	116944.0	65919.0	105715.0	102540.0	117823.0	151732.0	157695.0	214373.0	160508.0	137405.0
Metabolism|Energy Metabolism|Oxidative phosphorylation	184510.0	208859.0	154835.0	141382.0	91498.0	134757.0	177516.0	192920.0	168027.0	133428.0	157172.0	175873.0	180746.0	202855.0	142880.0	137727.0	167244.0	184065.0	119784.0	156301.0	196558.0	160114.0	295942.0	192972.0	198142.0	288737.0	217253.0	118587.0	146318.0	203487.0	146978.0	140128.0	234463.0	214911.0	203277.0	207877.0	156539.0	350300.0	267515.0	197722.0	362208.0	133939.0	211794.0	148774.0	173066.0	280800.0	109951.0	103728.0	88824.0	99694.0	74678.0	157845.0	152382.0	126117.0	138225.0	216142.0	151626.0	86300.0	137094.0	130423.0	155485.0	180039.0	180799.0	253161.0	193707.0	170608.0
Metabolism|Energy Metabolism|Photosynthesis	55347.0	62035.0	50974.0	44939.0	26786.0	54554.0	62721.0	69607.0	60397.0	53736.0	48756.0	52947.0	54246.0	62665.0	47730.0	39603.0	50768.0	56779.0	33960.0	44048.0	54411.0	55697.0	73328.0	55436.0	55629.0	90198.0	58742.0	41182.0	48364.0	66404.0	48737.0	48977.0	97263.0	106644.0	73922.0	78590.0	52859.0	84179.0	64672.0	55570.0	91539.0	41522.0	68301.0	49435.0	52216.0	77370.0	54307.0	47423.0	37868.0	48186.0	35160.0	51284.0	46774.0	39017.0	48299.0	77937.0	48245.0	27788.0	42764.0	45514.0	52299.0	52314.0	48607.0	93270.0	75822.0	78984.0
Metabolism|Energy Metabolism|Photosynthesis - antenna proteins	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	4.0	0.0	0.0	0.0	0.0	0.0	0.0	4.0	0.0	0.0	0.0	0.0	340.0	119.0	0.0	0.0	4.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	8483.0	106.0	1024.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Metabolism|Energy Metabolism|Photosynthesis proteins	56640.0	63503.0	51995.0	45749.0	27190.0	56022.0	64709.0	71453.0	62135.0	55432.0	49779.0	53905.0	55349.0	63909.0	48350.0	40478.0	51621.0	57591.0	34579.0	45100.0	55916.0	56720.0	77926.0	56201.0	56055.0	91257.0	60208.0	41718.0	49003.0	67218.0	49544.0	49819.0	97684.0	116378.0	74949.0	80827.0	53306.0	87581.0	67559.0	57838.0	96604.0	42458.0	71619.0	51945.0	55005.0	82207.0	55990.0	48776.0	39251.0	49532.0	36301.0	52233.0	47379.0	39657.0	48715.0	78843.0	49011.0	28234.0	43543.0	46288.0	53153.0	54143.0	50403.0	95283.0	77686.0	80623.0
Metabolism|Energy Metabolism|Sulfur metabolism	54752.0	61899.0	45811.0	42798.0	29545.0	45705.0	55341.0	61715.0	53212.0	46310.0	51228.0	55812.0	57194.0	63813.0	44884.0	48708.0	59101.0	65162.0	41299.0	55787.0	70684.0	51690.0	89456.0	64124.0	66915.0	89318.0	68192.0	35356.0	42285.0	56602.0	40529.0	45818.0	69972.0	63883.0	57912.0	57576.0	53202.0	88764.0	78017.0	63247.0	116711.0	42911.0	70346.0	50382.0	57224.0	91207.0	41394.0	36454.0	30915.0	35682.0	27056.0	47596.0	47128.0	38752.0	37850.0	62646.0	45571.0	26380.0	42811.0	39014.0	48921.0	48691.0	48254.0	71200.0	60927.0	61142.0
Metabolism|Enzyme Families|Cytochrome P450	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Metabolism|Enzyme Families|Peptidases	320628.0	361539.0	283169.0	254668.0	180129.0	257933.0	314151.0	357574.0	307978.0	262283.0	273102.0	296748.0	303980.0	359480.0	271506.0	221016.0	283171.0	314903.0	191288.0	253790.0	334999.0	285378.0	486481.0	305707.0	298715.0	488664.0	346783.0	203523.0	253550.0	338310.0	258416.0	264824.0	443675.0	390136.0	367424.0	367832.0	276576.0	489569.0	422154.0	354451.0	628624.0	243810.0	401372.0	295011.0	327379.0	519073.0	253871.0	222560.0	180307.0	221129.0	162193.0	284281.0	272060.0	222099.0	251346.0	364910.0	275339.0	158237.0	257944.0	254732.0	289242.0	320763.0	322124.0	490610.0	379232.0	364366.0
Metabolism|Enzyme Families|Protein kinases	57785.0	68807.0	47614.0	42457.0	28067.0	54134.0	73938.0	78252.0	68837.0	61470.0	47068.0	49847.0	51236.0	62786.0	44243.0	38879.0	41057.0	43207.0	31397.0	41834.0	61138.0	44183.0	138917.0	60384.0	55960.0	82551.0	70581.0	32251.0	38128.0	53253.0	40594.0	45712.0	69376.0	67793.0	61310.0	66677.0	39447.0	121382.0	103683.0	86292.0	169547.0	45335.0	104752.0	72725.0	88770.0	152653.0	46381.0	43471.0	34219.0	38906.0	29372.0	52487.0	48153.0	39894.0	40416.0	59127.0	43999.0	24748.0	36680.0	38785.0	47289.0	73127.0	71529.0	90033.0	77610.0	71242.0
Metabolism|Glycan Biosynthesis and Metabolism|Glycosaminoglycan biosynthesis - chondroitin sulfate	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Metabolism|Glycan Biosynthesis and Metabolism|Glycosaminoglycan degradation	41289.0	44092.0	29305.0	28341.0	9958.0	2349.0	1377.0	1566.0	1444.0	1046.0	26157.0	29995.0	31995.0	28600.0	18968.0	28108.0	37115.0	42332.0	25828.0	34414.0	39778.0	25111.0	18361.0	32210.0	34881.0	46652.0	31455.0	21540.0	30251.0	36374.0	24522.0	19971.0	16480.0	19375.0	18605.0	12376.0	28167.0	35938.0	36047.0	23623.0	33943.0	19548.0	3710.0	2660.0	3250.0	5461.0	949.0	1928.0	1541.0	2255.0	1655.0	22362.0	19137.0	17954.0	18146.0	25859.0	23005.0	13860.0	24530.0	17091.0	20963.0	5326.0	4013.0	4200.0	3630.0	2959.0
Metabolism|Glycan Biosynthesis and Metabolism|Glycosphingolipid biosynthesis - ganglio series	30438.0	32367.0	21390.0	20453.0	6915.0	1176.0	893.0	1202.0	1028.0	605.0	19242.0	21696.0	22825.0	21686.0	14561.0	22587.0	29894.0	34073.0	20577.0	27631.0	32036.0	18561.0	13031.0	18167.0	19246.0	32579.0	20870.0	15227.0	21996.0	27246.0	18149.0	15021.0	8425.0	11759.0	9752.0	6571.0	21529.0	25979.0	27319.0	17778.0	26944.0	14586.0	3602.0	2360.0	3026.0	4759.0	675.0	1505.0	1041.0	1670.0	1012.0	15512.0	14820.0	13766.0	8820.0	17000.0	17646.0	10542.0	18261.0	12629.0	15430.0	4001.0	3418.0	2005.0	2880.0	2344.0
Metabolism|Glycan Biosynthesis and Metabolism|Glycosphingolipid biosynthesis - globo series	41566.0	44659.0	30317.0	28733.0	12990.0	6160.0	7571.0	9942.0	8058.0	6328.0	27207.0	30867.0	32238.0	32395.0	23140.0	34447.0	45719.0	52040.0	31318.0	41411.0	49864.0	35837.0	20232.0	26386.0	27608.0	46453.0	29925.0	21951.0	30899.0	38929.0	27056.0	23215.0	23653.0	32109.0	25614.0	20215.0	31355.0	35000.0	36084.0	26255.0	36803.0	22928.0	9675.0	6876.0	7540.0	10474.0	5501.0	5386.0	4196.0	5833.0	4320.0	28075.0	24157.0	21077.0	16692.0	30844.0	25713.0	15317.0	26199.0	19722.0	22848.0	8531.0	7003.0	11090.0	12897.0	14115.0
Metabolism|Glycan Biosynthesis and Metabolism|Glycosphingolipid biosynthesis - lacto and neolacto series	2.0	3.0	24.0	44.0	5.0	0.0	0.0	0.0	0.0	0.0	19.0	48.0	64.0	6.0	7.0	0.0	2.0	3.0	176.0	20.0	17.0	141.0	269.0	92.0	74.0	94.0	110.0	12.0	22.0	15.0	13.0	0.0	0.0	0.0	0.0	0.0	0.0	10.0	19.0	1.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	9.0	131.0	166.0	570.0	43.0	5.0	0.0	0.0	0.0	0.0	0.0
Metabolism|Glycan Biosynthesis and Metabolism|Glycosylphosphatidylinositol(GPI)-anchor biosynthesis	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Metabolism|Glycan Biosynthesis and Metabolism|Glycosyltransferases	77736.0	85069.0	66010.0	57953.0	34234.0	53850.0	60365.0	63162.0	56153.0	47909.0	59891.0	65583.0	68503.0	82842.0	59953.0	50999.0	66216.0	71951.0	43307.0	60909.0	80245.0	53185.0	124592.0	70335.0	73199.0	98824.0	81613.0	39406.0	51310.0	69614.0	51804.0	51597.0	61539.0	70007.0	59721.0	61186.0	45715.0	123599.0	109830.0	86504.0	159921.0	53901.0	87924.0	64277.0	73811.0	120913.0	45292.0	44837.0	36818.0	42916.0	31210.0	67797.0	54775.0	45857.0	41694.0	68261.0	61258.0	33597.0	51629.0	49634.0	58997.0	78161.0	73742.0	90884.0	88246.0	72184.0
Metabolism|Glycan Biosynthesis and Metabolism|Lipopolysaccharide biosynthesis	69717.0	77153.0	54040.0	48584.0	22233.0	46329.0	49441.0	45684.0	43258.0	42105.0	57398.0	64146.0	67214.0	68359.0	40550.0	48188.0	57257.0	61790.0	40106.0	60446.0	74249.0	38802.0	121355.0	70257.0	75393.0	93738.0	81654.0	35239.0	48978.0	61983.0	46828.0	47025.0	17392.0	34871.0	31312.0	32974.0	36024.0	131796.0	110818.0	78317.0	156426.0	49210.0	75736.0	58591.0	66674.0	110598.0	39170.0	33096.0	36165.0	33438.0	27355.0	47454.0	40457.0	37154.0	23465.0	44010.0	52861.0	31315.0	47668.0	43949.0	56487.0	41164.0	41203.0	54642.0	53786.0	31287.0
Metabolism|Glycan Biosynthesis and Metabolism|Lipopolysaccharide biosynthesis proteins	100894.0	113633.0	80795.0	72572.0	37590.0	72922.0	87190.0	82715.0	76804.0	69955.0	89401.0	98467.0	102663.0	107684.0	65435.0	79054.0	94618.0	102394.0	65202.0	98206.0	118919.0	70254.0	182627.0	97390.0	99739.0	146591.0	116942.0	53508.0	73266.0	89627.0	69230.0	73996.0	49919.0	69578.0	68009.0	68355.0	62695.0	181649.0	157044.0	115719.0	228097.0	77987.0	119409.0	90205.0	105048.0	165469.0	60773.0	53817.0	52929.0	51161.0	40952.0	78668.0	67109.0	59153.0	49104.0	72927.0	83045.0	48247.0	73007.0	67601.0	87280.0	75514.0	75578.0	98096.0	90017.0	56735.0
Metabolism|Glycan Biosynthesis and Metabolism|N-Glycan biosynthesis	3768.0	3655.0	2744.0	2633.0	2108.0	916.0	118.0	94.0	154.0	179.0	2788.0	3025.0	3247.0	4126.0	3755.0	3709.0	4804.0	5400.0	3071.0	4063.0	6048.0	4341.0	4543.0	5609.0	6713.0	5824.0	5801.0	2610.0	4096.0	4483.0	3361.0	2582.0	1866.0	5064.0	2747.0	2739.0	2351.0	6589.0	6629.0	4856.0	7973.0	2931.0	2763.0	1914.0	2572.0	4554.0	195.0	518.0	455.0	802.0	571.0	3064.0	3155.0	2140.0	1658.0	3710.0	3360.0	1769.0	2849.0	2518.0	2902.0	3007.0	2981.0	2015.0	2959.0	2163.0
Metabolism|Glycan Biosynthesis and Metabolism|Other glycan degradation	120166.0	129369.0	89330.0	86855.0	30053.0	32402.0	46026.0	52753.0	45357.0	45174.0	98494.0	111307.0	115281.0	111018.0	76269.0	77603.0	101365.0	115490.0	70566.0	93358.0	110208.0	76719.0	65098.0	86114.0	86919.0	168928.0	98934.0	63988.0	85273.0	115747.0	77135.0	84481.0	74935.0	69347.0	60540.0	56512.0	86235.0	104771.0	106976.0	83902.0	137078.0	76632.0	51037.0	33666.0	34417.0	49402.0	43636.0	35295.0	26646.0	35411.0	24140.0	74226.0	75464.0	70472.0	50586.0	94782.0	85839.0	51245.0	77726.0	63296.0	81044.0	16506.0	15396.0	49369.0	49576.0	51359.0
Metabolism|Glycan Biosynthesis and Metabolism|Other types of O-glycan biosynthesis	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Metabolism|Glycan Biosynthesis and Metabolism|Peptidoglycan biosynthesis	125579.0	141003.0	113783.0	101974.0	87164.0	125333.0	145113.0	164775.0	142286.0	120866.0	107843.0	115544.0	118420.0	140985.0	107002.0	94373.0	116941.0	129842.0	81046.0	103510.0	131650.0	120279.0	191681.0	119936.0	118299.0	189958.0	133595.0	83424.0	101994.0	136652.0	105116.0	107020.0	203009.0	164021.0	159601.0	162805.0	118360.0	195917.0	157505.0	134604.0	232409.0	93527.0	171235.0	122876.0	131758.0	199867.0	122118.0	110706.0	87331.0	110695.0	79177.0	122085.0	113955.0	89568.0	107474.0	156765.0	106693.0	61242.0	98743.0	101932.0	115315.0	131162.0	123163.0	210074.0	169818.0	167276.0
Metabolism|Glycan Biosynthesis and Metabolism|Various types of N-glycan biosynthesis	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	50.0	6.0	30.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Metabolism|Lipid Metabolism|Arachidonic acid metabolism	4568.0	5173.0	3325.0	3191.0	1893.0	3726.0	3829.0	4395.0	3647.0	2435.0	4220.0	4104.0	4298.0	5386.0	3921.0	3617.0	4385.0	4732.0	3134.0	4176.0	6427.0	3282.0	12626.0	6172.0	6693.0	5840.0	6374.0	1738.0	2137.0	3441.0	2695.0	2931.0	3234.0	3982.0	2899.0	2940.0	3470.0	9391.0	8453.0	7063.0	13668.0	3788.0	9035.0	6673.0	8798.0	12197.0	1627.0	2506.0	2048.0	2576.0	1827.0	4408.0	3510.0	3104.0	2089.0	3994.0	4209.0	2389.0	3497.0	3462.0	4643.0	9029.0	9096.0	7966.0	5078.0	4660.0
Metabolism|Lipid Metabolism|Biosynthesis of unsaturated fatty acids	23358.0	28875.0	21013.0	18615.0	11280.0	26754.0	36147.0	36786.0	33079.0	32194.0	21005.0	22466.0	24037.0	30727.0	22852.0	16125.0	19099.0	19791.0	13021.0	18587.0	28999.0	17212.0	68681.0	39172.0	40700.0	36702.0	37138.0	13777.0	16517.0	23510.0	19500.0	22036.0	26601.0	23062.0	22994.0	26214.0	18090.0	56278.0	47915.0	39609.0	80851.0	20101.0	52663.0	36239.0	43163.0	72746.0	24955.0	21460.0	18512.0	19426.0	15109.0	21022.0	21243.0	17790.0	15936.0	24043.0	21470.0	12173.0	17380.0	18553.0	21478.0	35024.0	34452.0	45927.0	44975.0	35920.0
Metabolism|Lipid Metabolism|Ether lipid metabolism	4.0	3.0	0.0	0.0	8.0	54.0	9.0	7.0	7.0	9.0	18.0	3.0	3.0	51.0	9.0	16.0	5.0	8.0	2.0	0.0	1.0	137.0	127.0	307.0	157.0	377.0	314.0	0.0	2.0	0.0	0.0	7.0	23.0	293.0	295.0	230.0	43.0	1.0	1.0	8.0	6.0	12.0	172.0	25.0	33.0	16.0	53.0	108.0	52.0	145.0	57.0	854.0	0.0	13.0	293.0	421.0	6.0	3.0	29.0	16.0	26.0	66.0	57.0	41.0	15.0	172.0
Metabolism|Lipid Metabolism|Fatty acid biosynthesis	70749.0	77773.0	55669.0	52993.0	53474.0	58209.0	64793.0	73245.0	63475.0	47718.0	66051.0	72237.0	74106.0	90916.0	68123.0	54987.0	66757.0	72399.0	47612.0	59852.0	80837.0	64690.0	119933.0	77838.0	78466.0	117213.0	86113.0	44427.0	53151.0	76039.0	54694.0	55632.0	102251.0	83753.0	82337.0	83163.0	68499.0	122039.0	102366.0	78745.0	145785.0	55013.0	86064.0	63532.0	70737.0	113242.0	48179.0	47817.0	37911.0	46894.0	33374.0	71448.0	66398.0	52644.0	61137.0	92079.0	68671.0	37811.0	60733.0	57532.0	63673.0	89268.0	84268.0	111512.0	89581.0	83600.0
Metabolism|Lipid Metabolism|Fatty acid elongation in mitochondria	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1516.0	2140.0	245.0	779.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Metabolism|Lipid Metabolism|Fatty acid metabolism	55373.0	66793.0	48327.0	42285.0	21991.0	56278.0	74215.0	79061.0	69483.0	65480.0	44948.0	46399.0	48213.0	57992.0	42004.0	33593.0	38903.0	42316.0	27788.0	38130.0	57598.0	42591.0	119471.0	53411.0	48203.0	72325.0	60391.0	30779.0	37492.0	50367.0	41688.0	47804.0	68946.0	59173.0	54582.0	58715.0	38061.0	108672.0	90877.0	79638.0	150549.0	43936.0	100967.0	69315.0	81297.0	135803.0	53474.0	45431.0	37712.0	43529.0	33637.0	45403.0	44820.0	37276.0	33539.0	54671.0	42641.0	25157.0	39035.0	42688.0	48137.0	62144.0	63017.0	91963.0	75398.0	69065.0
Metabolism|Lipid Metabolism|Glycerolipid metabolism	43789.0	50056.0	40098.0	37016.0	40562.0	50836.0	57100.0	69909.0	57999.0	42243.0	40764.0	43134.0	43360.0	57126.0	44120.0	37257.0	46263.0	50537.0	33399.0	41302.0	55343.0	54721.0	85366.0	55723.0	55338.0	75976.0	58700.0	31166.0	37438.0	50790.0	39530.0	36672.0	89750.0	82771.0	78506.0	77990.0	45721.0	79880.0	63448.0	54001.0	94743.0	36326.0	67655.0	51297.0	58047.0	92091.0	37287.0	35240.0	27384.0	35069.0	26724.0	54508.0	47830.0	36989.0	51440.0	72412.0	41358.0	22866.0	39524.0	38379.0	41735.0	71320.0	66849.0	94913.0	73349.0	74043.0
Metabolism|Lipid Metabolism|Glycerophospholipid metabolism	72865.0	82361.0	67219.0	59785.0	56217.0	75372.0	90583.0	97690.0	86285.0	71947.0	62966.0	71392.0	73954.0	87527.0	65774.0	58855.0	72060.0	78304.0	50707.0	66755.0	86616.0	75862.0	157324.0	91267.0	92279.0	121349.0	99689.0	54527.0	63225.0	85561.0	64585.0	59308.0	123389.0	106383.0	108119.0	110084.0	71299.0	146250.0	115900.0	91746.0	172132.0	54504.0	117497.0	88676.0	97638.0	160656.0	70231.0	60530.0	52890.0	59489.0	45803.0	71730.0	66118.0	52172.0	71552.0	101518.0	64574.0	36887.0	65473.0	62292.0	65224.0	100864.0	97612.0	137626.0	110137.0	105285.0
Metabolism|Lipid Metabolism|Linoleic acid metabolism	11702.0	12249.0	9339.0	9388.0	6353.0	5355.0	7475.0	10443.0	8364.0	5529.0	10593.0	11837.0	11993.0	12808.0	8854.0	740.0	1306.0	1531.0	2103.0	1195.0	1164.0	5267.0	9570.0	13782.0	13882.0	22753.0	13620.0	5970.0	7386.0	11414.0	7365.0	8744.0	13415.0	7780.0	10344.0	10588.0	5873.0	11836.0	10200.0	7619.0	12023.0	7751.0	5767.0	4561.0	4516.0	6105.0	5675.0	4135.0	3404.0	4512.0	3350.0	8473.0	9397.0	7772.0	8818.0	12349.0	10477.0	6013.0	8257.0	7716.0	9814.0	4392.0	4515.0	10125.0	8459.0	10524.0
Metabolism|Lipid Metabolism|Lipid biosynthesis proteins	104742.0	117496.0	85903.0	78741.0	60894.0	83076.0	99963.0	106597.0	95034.0	80752.0	88554.0	96939.0	100679.0	117502.0	86419.0	73728.0	89165.0	97417.0	62263.0	81391.0	104687.0	83926.0	156657.0	103713.0	104410.0	154918.0	112624.0	64028.0	78951.0	108335.0	80313.0	82382.0	125468.0	107408.0	102688.0	106965.0	83709.0	164622.0	138333.0	108773.0	196006.0	75463.0	121813.0	87437.0	96602.0	151411.0	76647.0	68436.0	57339.0	67193.0	49431.0	90049.0	86926.0	71044.0	71244.0	115536.0	89457.0	50377.0	78117.0	77541.0	88076.0	100862.0	97540.0	146546.0	122111.0	112410.0
Metabolism|Lipid Metabolism|Primary bile acid biosynthesis	10195.0	11859.0	10273.0	9438.0	3688.0	7428.0	11152.0	12183.0	10634.0	10821.0	10223.0	11489.0	11763.0	12905.0	9339.0	4196.0	6273.0	7078.0	4092.0	5226.0	5534.0	5863.0	6371.0	9383.0	9030.0	16963.0	9006.0	6092.0	7623.0	11400.0	8356.0	10295.0	12731.0	7496.0	8026.0	8807.0	6932.0	8542.0	8801.0	7748.0	12139.0	7592.0	8902.0	5934.0	5802.0	7680.0	9326.0	6915.0	5628.0	6722.0	5047.0	7595.0	10297.0	8314.0	6963.0	10178.0	9493.0	5523.0	7513.0	7354.0	8923.0	2185.0	2014.0	12222.0	12399.0	11696.0
Metabolism|Lipid Metabolism|Secondary bile acid biosynthesis	10195.0	11859.0	10273.0	9438.0	3688.0	7413.0	11150.0	12182.0	10634.0	10821.0	10222.0	11487.0	11763.0	12853.0	9335.0	4196.0	6273.0	7076.0	4092.0	5226.0	5534.0	5787.0	6246.0	9079.0	8879.0	16588.0	8859.0	6092.0	7623.0	11400.0	8356.0	10295.0	12730.0	7493.0	8009.0	8795.0	6895.0	8542.0	8801.0	7748.0	12138.0	7587.0	8902.0	5934.0	5802.0	7680.0	9326.0	6915.0	5628.0	6722.0	5046.0	7595.0	10297.0	8313.0	6963.0	10176.0	9493.0	5523.0	7512.0	7354.0	8922.0	2185.0	2013.0	12221.0	12395.0	11694.0
Metabolism|Lipid Metabolism|Sphingolipid metabolism	67276.0	72565.0	51471.0	50075.0	21952.0	18541.0	26217.0	29724.0	25788.0	25621.0	60431.0	70894.0	73704.0	67701.0	47740.0	50069.0	65822.0	75211.0	45484.0	60291.0	72113.0	57796.0	43939.0	61240.0	64106.0	108867.0	67454.0	39355.0	50293.0	65955.0	44763.0	51559.0	50736.0	58250.0	46787.0	42921.0	50702.0	58412.0	60276.0	48608.0	78820.0	47937.0	29157.0	20268.0	20858.0	29870.0	24320.0	19046.0	14956.0	19726.0	14432.0	48919.0	45794.0	41164.0	35249.0	67408.0	52452.0	31599.0	49682.0	41184.0	49248.0	8920.0	7807.0	29538.0	27743.0	34325.0
Metabolism|Lipid Metabolism|Steroid biosynthesis	0.0	0.0	0.0	0.0	0.0	11.0	1.0	1.0	0.0	3.0	7.0	1.0	3.0	8.0	0.0	3.0	2.0	1.0	0.0	0.0	0.0	40.0	14.0	4548.0	6421.0	737.0	2337.0	0.0	0.0	0.0	0.0	1.0	1.0	998.0	12.0	120.0	0.0	0.0	0.0	0.0	1.0	4.0	3.0	1.0	1.0	1.0	1.0	4.0	2.0	5.0	4.0	2.0	0.0	0.0	0.0	2.0	1.0	0.0	1.0	1.0	1.0	2.0	0.0	0.0	0.0	1.0
Metabolism|Lipid Metabolism|Steroid hormone biosynthesis	3627.0	4203.0	3203.0	4033.0	2685.0	311.0	796.0	1197.0	876.0	508.0	6552.0	8500.0	9054.0	7003.0	4925.0	9131.0	11884.0	13560.0	8821.0	11363.0	13264.0	7766.0	8414.0	13109.0	15314.0	13438.0	11656.0	2884.0	2997.0	4270.0	2728.0	4449.0	2673.0	4867.0	3102.0	2266.0	8246.0	6957.0	7389.0	4950.0	10491.0	4396.0	3071.0	1959.0	2472.0	4480.0	145.0	148.0	102.0	160.0	122.0	2897.0	4137.0	3221.0	2280.0	6299.0	5554.0	3757.0	8014.0	4071.0	4371.0	1688.0	1760.0	526.0	391.0	259.0
Metabolism|Lipid Metabolism|Synthesis and degradation of ketone bodies	1528.0	2100.0	3167.0	2514.0	3718.0	4740.0	3453.0	4963.0	3713.0	2514.0	2196.0	1936.0	2122.0	5228.0	4954.0	1732.0	3496.0	3796.0	2033.0	2263.0	3504.0	2689.0	8832.0	3966.0	3840.0	4110.0	4081.0	1828.0	1929.0	3195.0	2755.0	1653.0	5433.0	4142.0	3738.0	3623.0	3177.0	5952.0	3666.0	3030.0	5831.0	1613.0	4936.0	3556.0	4214.0	6775.0	1768.0	2705.0	1661.0	2778.0	2148.0	3589.0	3362.0	2042.0	2115.0	3866.0	3699.0	1937.0	4612.0	4346.0	3497.0	10428.0	10071.0	10210.0	10282.0	9922.0
Metabolism|Lipid Metabolism|alpha-Linolenic acid metabolism	2323.0	3238.0	2259.0	1933.0	1026.0	2834.0	4437.0	4149.0	3799.0	3821.0	1887.0	2082.0	2255.0	3003.0	2009.0	1861.0	1849.0	1799.0	1369.0	2418.0	4145.0	1408.0	12686.0	1978.0	993.0	2450.0	3691.0	1352.0	1672.0	1866.0	1645.0	2056.0	1084.0	2043.0	1922.0	2352.0	1004.0	10163.0	8981.0	6857.0	14991.0	2389.0	8472.0	5646.0	7462.0	13718.0	1715.0	1676.0	1750.0	1180.0	1131.0	2208.0	2411.0	1743.0	1107.0	1906.0	1816.0	989.0	1476.0	1439.0	1851.0	4965.0	5201.0	4465.0	4130.0	2457.0
Metabolism|Metabolism of Cofactors and Vitamins|Biotin metabolism	34360.0	37879.0	25873.0	23487.0	12385.0	18700.0	20789.0	20984.0	19068.0	16989.0	23527.0	25953.0	26822.0	28762.0	18761.0	21168.0	25555.0	28013.0	17836.0	25250.0	30449.0	22794.0	40152.0	26343.0	27787.0	42729.0	30606.0	19538.0	25053.0	32992.0	23126.0	20547.0	26000.0	27122.0	26717.0	26463.0	23396.0	43748.0	40194.0	29192.0	50514.0	19095.0	24319.0	18717.0	21724.0	35699.0	13775.0	12674.0	11607.0	12536.0	10029.0	23559.0	21020.0	18353.0	19299.0	28030.0	22652.0	13111.0	21601.0	20325.0	23681.0	18407.0	19176.0	29011.0	23696.0	20553.0
Metabolism|Metabolism of Cofactors and Vitamins|Folate biosynthesis	78717.0	89709.0	64623.0	57629.0	35431.0	69874.0	76639.0	77927.0	71100.0	67964.0	68379.0	71005.0	73153.0	79999.0	55136.0	62182.0	71514.0	78696.0	48547.0	67575.0	82195.0	67458.0	110065.0	74602.0	77977.0	111608.0	81174.0	49126.0	62066.0	80221.0	60554.0	64098.0	92512.0	84372.0	77000.0	79533.0	63033.0	106190.0	95759.0	82484.0	144832.0	58298.0	91167.0	68300.0	76064.0	117332.0	64918.0	58369.0	47714.0	58034.0	42866.0	68405.0	57156.0	49133.0	49609.0	82774.0	62162.0	36189.0	57230.0	57734.0	67807.0	60426.0	56511.0	101927.0	78862.0	78042.0
Metabolism|Metabolism of Cofactors and Vitamins|Lipoic acid metabolism	15112.0	17500.0	12104.0	11169.0	6365.0	9230.0	11719.0	12457.0	11036.0	10409.0	10942.0	11626.0	12150.0	13905.0	9721.0	11991.0	13730.0	15059.0	10082.0	13091.0	15735.0	9574.0	17870.0	11268.0	10856.0	16635.0	12314.0	8203.0	11683.0	14472.0	11452.0	10336.0	8996.0	10386.0	7540.0	7928.0	9634.0	24220.0	20209.0	14278.0	24807.0	9008.0	14956.0	10268.0	11163.0	18327.0	9131.0	7835.0	6970.0	7206.0	5539.0	10920.0	11601.0	9163.0	5387.0	9718.0	10108.0	5841.0	11127.0	9371.0	9976.0	9588.0	9234.0	14138.0	12447.0	10030.0
Metabolism|Metabolism of Cofactors and Vitamins|Nicotinate and nicotinamide metabolism	87317.0	103388.0	77901.0	69137.0	38580.0	80280.0	101543.0	110046.0	96896.0	93161.0	73617.0	79293.0	82037.0	91315.0	65907.0	56126.0	69315.0	76683.0	47123.0	65080.0	85373.0	71758.0	137317.0	69457.0	61002.0	122096.0	82503.0	54563.0	67240.0	89273.0	70053.0	77613.0	112970.0	94031.0	90193.0	95637.0	69751.0	133258.0	112216.0	98682.0	179522.0	65669.0	124241.0	87863.0	98504.0	154465.0	83871.0	70046.0	58976.0	68671.0	51541.0	70617.0	67520.0	58176.0	59746.0	92018.0	67642.0	40104.0	59484.0	64109.0	75341.0	66139.0	63698.0	126575.0	108097.0	103913.0
Metabolism|Metabolism of Cofactors and Vitamins|One carbon pool by folate	104419.0	115688.0	87787.0	79189.0	56853.0	80490.0	90897.0	100367.0	88049.0	77736.0	87458.0	95078.0	97687.0	110748.0	81934.0	71211.0	87792.0	97371.0	60353.0	78954.0	99221.0	88430.0	135042.0	97037.0	97932.0	159072.0	109920.0	67634.0	85003.0	113311.0	84046.0	82556.0	131356.0	115986.0	110301.0	110902.0	84773.0	145758.0	123033.0	100801.0	173403.0	74303.0	107646.0	79338.0	85688.0	132448.0	78668.0	71600.0	57655.0	72204.0	51666.0	90589.0	82256.0	68178.0	78786.0	118171.0	86044.0	49737.0	78659.0	78878.0	91922.0	82847.0	78894.0	137620.0	112837.0	112849.0
Metabolism|Metabolism of Cofactors and Vitamins|Pantothenate and CoA biosynthesis	98014.0	110795.0	82642.0	74568.0	57271.0	88657.0	102438.0	111252.0	97931.0	83489.0	84460.0	90951.0	93058.0	105372.0	77000.0	72688.0	85795.0	94382.0	59428.0	78948.0	102570.0	94874.0	157145.0	101843.0	103112.0	153161.0	113120.0	66533.0	80421.0	108068.0	79796.0	79506.0	145227.0	130379.0	121964.0	123410.0	84681.0	151904.0	129449.0	109647.0	190687.0	74536.0	123738.0	91963.0	103377.0	163278.0	78950.0	70242.0	56470.0	68938.0	51554.0	92014.0	82505.0	66825.0	78097.0	122326.0	80723.0	46411.0	72667.0	75361.0	89130.0	96147.0	93510.0	149510.0	112896.0	116683.0
Metabolism|Metabolism of Cofactors and Vitamins|Porphyrin and chlorophyll metabolism	115206.0	116792.0	82072.0	74711.0	69335.0	79971.0	67490.0	68995.0	63348.0	55970.0	93455.0	104448.0	106490.0	113214.0	77037.0	87487.0	102301.0	112349.0	67225.0	99570.0	119519.0	119853.0	175353.0	102837.0	109791.0	190402.0	138768.0	77425.0	79437.0	115403.0	70094.0	71382.0	139066.0	174231.0	141188.0	154696.0	112833.0	174336.0	149790.0	108025.0	196010.0	75413.0	91374.0	82181.0	93456.0	158236.0	50272.0	47145.0	42681.0	51165.0	41486.0	98391.0	84032.0	73342.0	82723.0	156852.0	80298.0	45038.0	81526.0	73409.0	85320.0	85639.0	91929.0	149405.0	86976.0	107877.0
Metabolism|Metabolism of Cofactors and Vitamins|Retinol metabolism	13223.0	15038.0	9804.0	8832.0	3916.0	7936.0	9397.0	10682.0	9105.0	7546.0	8610.0	8387.0	8499.0	10625.0	7781.0	4343.0	4214.0	4556.0	3884.0	3783.0	7221.0	5499.0	14345.0	8959.0	9132.0	11626.0	9916.0	4632.0	6627.0	9232.0	7030.0	7744.0	10239.0	9234.0	6765.0	7534.0	2862.0	18557.0	16532.0	14456.0	24750.0	8713.0	14440.0	9130.0	10783.0	17373.0	6046.0	5571.0	4624.0	5329.0	4109.0	9055.0	9209.0	7847.0	4159.0	7574.0	9047.0	5091.0	7231.0	8197.0	8280.0	9896.0	9225.0	10663.0	9356.0	8680.0
Metabolism|Metabolism of Cofactors and Vitamins|Riboflavin metabolism	41808.0	47161.0	34706.0	31334.0	22543.0	30888.0	36799.0	40124.0	35148.0	31075.0	38545.0	42398.0	43467.0	48586.0	31815.0	30294.0	34521.0	37566.0	25346.0	34013.0	42312.0	32204.0	78061.0	42643.0	43468.0	65126.0	50454.0	25212.0	30610.0	41911.0	30260.0	33199.0	41746.0	40684.0	36286.0	38910.0	31289.0	76201.0	65110.0	49488.0	98091.0	33463.0	52342.0	39699.0	44670.0	74837.0	28072.0	24108.0	22607.0	23451.0	18513.0	36025.0	33031.0	28133.0	24228.0	42303.0	36212.0	21043.0	33682.0	30953.0	37464.0	34470.0	34281.0	50698.0	39576.0	37654.0
Metabolism|Metabolism of Cofactors and Vitamins|Thiamine metabolism	84231.0	95487.0	73437.0	65836.0	41242.0	79824.0	97429.0	104910.0	92827.0	78849.0	73176.0	78203.0	80543.0	94566.0	72262.0	59712.0	75293.0	82945.0	50128.0	66062.0	85247.0	79863.0	116743.0	80201.0	79977.0	129517.0	87100.0	57011.0	68340.0	95215.0	71487.0	71560.0	140870.0	110333.0	109053.0	111170.0	76505.0	109184.0	95600.0	86789.0	144539.0	62654.0	102138.0	74724.0	82575.0	124144.0	73758.0	63487.0	50912.0	64102.0	47912.0	76735.0	69228.0	57853.0	70456.0	105591.0	76300.0	43680.0	66390.0	71368.0	79377.0	89688.0	89575.0	148341.0	118245.0	114023.0
Metabolism|Metabolism of Cofactors and Vitamins|Ubiquinone and other terpenoid-quinone biosynthesis	56344.0	66821.0	49496.0	43776.0	22095.0	46122.0	63413.0	65755.0	58234.0	48375.0	45570.0	48786.0	50633.0	58588.0	38187.0	45083.0	50621.0	54741.0	37949.0	49955.0	62134.0	36548.0	105124.0	54111.0	54149.0	68430.0	59809.0	29352.0	40120.0	52191.0	41377.0	41992.0	45903.0	48783.0	40246.0	42850.0	31974.0	110306.0	93123.0	71441.0	135903.0	41930.0	82840.0	58187.0	68458.0	109678.0	35834.0	30161.0	28935.0	26942.0	22735.0	42250.0	47355.0	38011.0	26107.0	44595.0	43429.0	24424.0	38644.0	36008.0	41134.0	56924.0	59209.0	73217.0	62014.0	41788.0
Metabolism|Metabolism of Cofactors and Vitamins|Vitamin B6 metabolism	43467.0	50412.0	35839.0	32632.0	20163.0	35053.0	45823.0	48010.0	42845.0	38990.0	35406.0	38072.0	39253.0	42935.0	30238.0	30241.0	35927.0	39588.0	25205.0	34454.0	43906.0	34638.0	62536.0	36167.0	33567.0	60082.0	41827.0	25420.0	32519.0	43016.0	32833.0	35134.0	48432.0	42754.0	40421.0	41314.0	32968.0	59978.0	54053.0	45719.0	79994.0	30859.0	52343.0	36414.0	41133.0	63595.0	33759.0	28034.0	24297.0	27563.0	21097.0	36261.0	35595.0	28897.0	28046.0	43135.0	31999.0	18606.0	27651.0	28517.0	35218.0	31682.0	30527.0	53567.0	44423.0	43831.0
Metabolism|Metabolism of Other Amino Acids|Cyanoamino acid metabolism	37721.0	43017.0	34241.0	34964.0	26861.0	30783.0	37539.0	48348.0	38887.0	29134.0	40286.0	49366.0	50240.0	49637.0	39644.0	41249.0	52302.0	58973.0	37060.0	46464.0	63613.0	61101.0	67269.0	46014.0	41524.0	87595.0	56757.0	30580.0	35576.0	51267.0	35673.0	34369.0	79442.0	83639.0	72351.0	65390.0	44524.0	66567.0	57408.0	50826.0	77268.0	35645.0	51664.0	36860.0	41411.0	61598.0	26302.0	23164.0	18874.0	23041.0	17520.0	45369.0	43368.0	32278.0	47013.0	66284.0	35042.0	20385.0	35454.0	33278.0	37911.0	41767.0	38910.0	54424.0	44048.0	45941.0
Metabolism|Metabolism of Other Amino Acids|D-Alanine metabolism	15823.0	17943.0	16070.0	14122.0	11267.0	19756.0	23636.0	27585.0	23344.0	16392.0	14405.0	14283.0	14441.0	19599.0	15732.0	9687.0	12901.0	14240.0	8777.0	10525.0	14473.0	13691.0	28621.0	15521.0	14583.0	23946.0	17713.0	10153.0	13125.0	17437.0	14522.0	13704.0	30762.0	21010.0	22266.0	22530.0	13512.0	27725.0	21785.0	19664.0	33497.0	12613.0	25820.0	18375.0	20844.0	32433.0	15847.0	15410.0	11451.0	15502.0	11123.0	16975.0	15975.0	11668.0	14128.0	20044.0	15990.0	8765.0	14498.0	15282.0	16173.0	27502.0	27128.0	38089.0	27674.0	25955.0
Metabolism|Metabolism of Other Amino Acids|D-Arginine and D-ornithine metabolism	66.0	154.0	110.0	313.0	617.0	848.0	430.0	1716.0	948.0	162.0	338.0	171.0	91.0	237.0	108.0	229.0	14.0	5.0	363.0	26.0	54.0	268.0	155.0	368.0	193.0	431.0	221.0	9.0	47.0	34.0	52.0	13.0	1044.0	539.0	565.0	441.0	417.0	73.0	99.0	202.0	105.0	123.0	505.0	514.0	539.0	547.0	112.0	167.0	37.0	193.0	224.0	182.0	775.0	388.0	126.0	116.0	31.0	8.0	16.0	58.0	78.0	66.0	26.0	367.0	516.0	362.0
Metabolism|Metabolism of Other Amino Acids|D-Glutamine and D-glutamate metabolism	28780.0	32161.0	25839.0	22779.0	15281.0	22954.0	25805.0	28305.0	24890.0	22615.0	24093.0	25760.0	26366.0	29592.0	20910.0	18940.0	23668.0	26553.0	16123.0	21479.0	24826.0	22439.0	35287.0	23882.0	23773.0	41253.0	27316.0	17328.0	21983.0	29327.0	21966.0	22895.0	34208.0	29607.0	27738.0	28126.0	21888.0	37235.0	31749.0	26710.0	45551.0	20578.0	28619.0	21037.0	22537.0	34175.0	21550.0	19048.0	15497.0	19499.0	14249.0	24613.0	22650.0	18890.0	19845.0	30160.0	23380.0	13659.0	20529.0	21218.0	25634.0	19390.0	18151.0	36717.0	28776.0	28768.0
Metabolism|Metabolism of Other Amino Acids|Glutathione metabolism	56073.0	65110.0	48393.0	42721.0	23283.0	48911.0	61034.0	66074.0	57730.0	52843.0	46311.0	49405.0	51378.0	64437.0	48345.0	42724.0	52806.0	57136.0	35767.0	48623.0	68972.0	42146.0	111594.0	46680.0	43665.0	68955.0	57390.0	29089.0	37175.0	50966.0	40396.0	45386.0	56189.0	55202.0	45819.0	49246.0	38802.0	110520.0	92472.0	76243.0	146374.0	44520.0	93075.0	66025.0	75872.0	123170.0	48117.0	41387.0	35431.0	39165.0	29668.0	47436.0	44129.0	37527.0	29621.0	50134.0	47773.0	26814.0	37702.0	40209.0	47769.0	67274.0	64657.0	83779.0	80539.0	64595.0
Metabolism|Metabolism of Other Amino Acids|Phosphonate and phosphinate metabolism	13525.0	15108.0	10724.0	10323.0	10988.0	9130.0	9030.0	11017.0	9330.0	7313.0	11991.0	12693.0	12182.0	14784.0	10820.0	9813.0	11798.0	13194.0	8454.0	10977.0	15000.0	10307.0	19148.0	13382.0	12927.0	22268.0	15242.0	7577.0	10528.0	12358.0	9451.0	10189.0	14246.0	11318.0	12117.0	10711.0	11990.0	21045.0	19830.0	15524.0	27340.0	10219.0	14664.0	11578.0	13627.0	21814.0	7481.0	6836.0	4890.0	6534.0	4715.0	11958.0	12491.0	9630.0	11559.0	11393.0	11005.0	6183.0	9664.0	9242.0	11615.0	10931.0	10419.0	13117.0	10131.0	9597.0
Metabolism|Metabolism of Other Amino Acids|Selenocompound metabolism	71803.0	82046.0	60926.0	55022.0	36342.0	67570.0	85210.0	95129.0	82188.0	69062.0	58828.0	63185.0	64667.0	77259.0	57721.0	47278.0	57111.0	62472.0	40391.0	52513.0	70412.0	60039.0	109509.0	69119.0	66297.0	103146.0	74482.0	45213.0	54821.0	73351.0	56770.0	59442.0	106301.0	83540.0	82540.0	82863.0	58509.0	109992.0	91530.0	78973.0	138301.0	52503.0	98058.0	71088.0	78817.0	122086.0	65033.0	55613.0	44769.0	54713.0	40802.0	61954.0	62244.0	49402.0	54029.0	81107.0	58029.0	33285.0	52724.0	55501.0	63723.0	76324.0	76803.0	118841.0	94023.0	88891.0
Metabolism|Metabolism of Other Amino Acids|Taurine and hypotaurine metabolism	22457.0	25847.0	20477.0	18709.0	10741.0	17694.0	21919.0	25784.0	21638.0	17620.0	19765.0	21304.0	21917.0	26457.0	19880.0	17646.0	22862.0	25332.0	15314.0	20287.0	25375.0	20146.0	31045.0	21607.0	22161.0	33180.0	23571.0	14366.0	18679.0	24367.0	18989.0	18481.0	28572.0	25677.0	23888.0	23583.0	19047.0	29663.0	27989.0	23557.0	39887.0	17201.0	25796.0	17680.0	20293.0	29701.0	14902.0	14186.0	11234.0	13786.0	10120.0	20126.0	20320.0	15971.0	15477.0	24436.0	21152.0	11938.0	18192.0	18697.0	20812.0	22740.0	21757.0	31946.0	28141.0	24722.0
Metabolism|Metabolism of Other Amino Acids|beta-Alanine metabolism	31026.0	36048.0	24637.0	22313.0	10998.0	25866.0	33542.0	32507.0	29713.0	24907.0	27482.0	29952.0	31103.0	34606.0	23329.0	25050.0	28828.0	31049.0	19695.0	29820.0	43486.0	29801.0	83074.0	32131.0	30248.0	47663.0	43513.0	20235.0	24084.0	33770.0	24083.0	22880.0	38187.0	39377.0	37060.0	38507.0	25397.0	75251.0	65967.0	52835.0	103212.0	26541.0	53665.0	38908.0	50028.0	89581.0	15438.0	15098.0	13713.0	13313.0	11314.0	27999.0	23511.0	20238.0	21314.0	39928.0	25293.0	14389.0	24001.0	21860.0	26251.0	44152.0	47744.0	51092.0	32946.0	29314.0
Metabolism|Metabolism of Terpenoids and Polyketides|Biosynthesis of 12-, 14- and 16-membered macrolides	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Metabolism|Metabolism of Terpenoids and Polyketides|Biosynthesis of ansamycins	17696.0	18563.0	12497.0	11768.0	8627.0	8966.0	10659.0	14287.0	11504.0	7905.0	11867.0	13318.0	12752.0	14953.0	11005.0	5749.0	6184.0	6818.0	5375.0	5851.0	10345.0	11270.0	24493.0	17123.0	15566.0	27900.0	19848.0	9392.0	10554.0	16045.0	10125.0	9918.0	22371.0	18483.0	18544.0	18254.0	10981.0	27540.0	23313.0	18419.0	32584.0	10838.0	18934.0	15335.0	18267.0	29104.0	7321.0	6579.0	5433.0	6941.0	5165.0	14899.0	13619.0	12054.0	13824.0	20601.0	10346.0	5808.0	9684.0	9258.0	11539.0	15497.0	16217.0	19738.0	12222.0	15364.0
Metabolism|Metabolism of Terpenoids and Polyketides|Biosynthesis of siderophore group nonribosomal peptides	6609.0	7975.0	5296.0	4925.0	3340.0	7445.0	9674.0	10305.0	9139.0	6422.0	5696.0	5823.0	6088.0	8129.0	6450.0	9007.0	8124.0	8495.0	6529.0	8187.0	12343.0	4300.0	29964.0	7449.0	5484.0	8135.0	11155.0	3093.0	3989.0	5340.0	4451.0	4853.0	6691.0	5115.0	5845.0	5817.0	4016.0	26255.0	23108.0	18696.0	37964.0	7058.0	22882.0	16018.0	20508.0	34365.0	4026.0	3964.0	3285.0	3542.0	2885.0	5155.0	7465.0	5732.0	2886.0	6456.0	6554.0	3477.0	5848.0	5477.0	5269.0	19166.0	19922.0	14110.0	9401.0	7192.0
Metabolism|Metabolism of Terpenoids and Polyketides|Biosynthesis of type II polyketide backbone	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Metabolism|Metabolism of Terpenoids and Polyketides|Biosynthesis of type II polyketide products	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Metabolism|Metabolism of Terpenoids and Polyketides|Biosynthesis of vancomycin group antibiotics	15745.0	17519.0	12286.0	10847.0	6005.0	6964.0	8450.0	9736.0	8333.0	6961.0	10936.0	12182.0	12492.0	13828.0	10155.0	10441.0	13270.0	14988.0	9161.0	11949.0	14489.0	12131.0	11072.0	11465.0	12182.0	18752.0	12371.0	8354.0	10670.0	13791.0	10569.0	10600.0	13793.0	14221.0	11955.0	11269.0	10560.0	14047.0	14227.0	11183.0	17335.0	9586.0	9163.0	6749.0	7202.0	10199.0	6830.0	6076.0	4870.0	6426.0	4766.0	11343.0	11578.0	9025.0	8231.0	13293.0	10848.0	6192.0	9806.0	10013.0	11108.0	6391.0	6018.0	11660.0	9602.0	9901.0
Metabolism|Metabolism of Terpenoids and Polyketides|Carotenoid biosynthesis	370.0	726.0	397.0	651.0	3975.0	1418.0	3770.0	5733.0	4109.0	843.0	941.0	741.0	385.0	1246.0	586.0	1116.0	50.0	18.0	1768.0	122.0	29.0	488.0	410.0	1674.0	2222.0	546.0	1010.0	74.0	335.0	238.0	475.0	78.0	3981.0	5083.0	1448.0	1842.0	183.0	301.0	244.0	388.0	175.0	354.0	2801.0	1404.0	1287.0	1052.0	53.0	202.0	179.0	160.0	320.0	940.0	4170.0	1959.0	627.0	278.0	586.0	184.0	259.0	693.0	546.0	2907.0	3367.0	3294.0	776.0	330.0
Metabolism|Metabolism of Terpenoids and Polyketides|Geraniol degradation	14242.0	17518.0	11545.0	10177.0	1206.0	12508.0	18244.0	16696.0	15545.0	13083.0	12032.0	12897.0	13749.0	15559.0	9393.0	10840.0	12205.0	12920.0	8548.0	13540.0	20876.0	8737.0	47418.0	17062.0	15799.0	18900.0	21665.0	6212.0	7639.0	11052.0	8586.0	10217.0	8365.0	8952.0	9738.0	10874.0	7797.0	40945.0	36177.0	29053.0	60747.0	12710.0	30524.0	20399.0	27110.0	50947.0	6390.0	7138.0	6334.0	5419.0	4659.0	11580.0	9430.0	8525.0	5767.0	12182.0	11100.0	6267.0	9170.0	8807.0	11699.0	22830.0	24230.0	21613.0	15281.0	9541.0
Metabolism|Metabolism of Terpenoids and Polyketides|Limonene and pinene degradation	16116.0	19008.0	12858.0	11713.0	9010.0	16151.0	22373.0	24288.0	20966.0	16404.0	12451.0	12521.0	12734.0	17696.0	12767.0	11636.0	12493.0	13035.0	9678.0	12643.0	20535.0	11361.0	46955.0	21205.0	19956.0	23128.0	23979.0	8214.0	11441.0	14381.0	12280.0	11018.0	19877.0	14556.0	16673.0	17952.0	13343.0	42405.0	35272.0	28259.0	56391.0	11693.0	33869.0	22927.0	28806.0	52374.0	10051.0	10408.0	8828.0	10574.0	8407.0	13994.0	14949.0	11129.0	12648.0	16237.0	13149.0	7302.0	11993.0	12488.0	12599.0	28677.0	30093.0	31784.0	22807.0	18543.0
Metabolism|Metabolism of Terpenoids and Polyketides|Polyketide sugar unit biosynthesis	41327.0	45266.0	32926.0	30236.0	18771.0	19544.0	24132.0	27472.0	23760.0	19360.0	33940.0	37695.0	38566.0	43283.0	31986.0	35384.0	46394.0	52315.0	30723.0	41130.0	48835.0	38861.0	32011.0	33949.0	36235.0	59791.0	37552.0	24565.0	31409.0	42133.0	30350.0	30814.0	45222.0	43993.0	37936.0	36031.0	39046.0	38392.0	38862.0	30966.0	49339.0	28461.0	24134.0	16630.0	18280.0	24403.0	18656.0	18020.0	13743.0	18826.0	12894.0	33041.0	32076.0	26540.0	26115.0	40209.0	33880.0	19517.0	31304.0	28225.0	33962.0	23099.0	21595.0	34055.0	31415.0	32234.0
Metabolism|Metabolism of Terpenoids and Polyketides|Prenyltransferases	56306.0	64093.0	52264.0	46491.0	32028.0	50634.0	61491.0	68808.0	59558.0	50152.0	49356.0	53174.0	54415.0	64954.0	49771.0	42287.0	53750.0	59827.0	37424.0	46593.0	57870.0	48513.0	72549.0	58461.0	61010.0	86285.0	61088.0	37361.0	48347.0	63374.0	49585.0	48431.0	78533.0	66194.0	59063.0	60833.0	46501.0	84949.0	68559.0	56854.0	95869.0	41785.0	68289.0	48525.0	52229.0	77286.0	47177.0	40050.0	33460.0	40653.0	30670.0	48030.0	50861.0	39787.0	39547.0	61705.0	49619.0	28218.0	44604.0	45106.0	50429.0	56153.0	54205.0	89617.0	76624.0	69112.0
Metabolism|Metabolism of Terpenoids and Polyketides|Sesquiterpenoid biosynthesis	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Metabolism|Metabolism of Terpenoids and Polyketides|Terpenoid backbone biosynthesis	85967.0	97336.0	80142.0	71260.0	55946.0	83411.0	95584.0	107600.0	93266.0	78881.0	77009.0	82788.0	84821.0	101438.0	77379.0	64103.0	82165.0	91331.0	55231.0	70733.0	86925.0	82610.0	115537.0	86134.0	87539.0	136449.0	92377.0	59028.0	72763.0	98912.0	75232.0	75679.0	136914.0	114276.0	107427.0	109023.0	78852.0	123660.0	99163.0	84669.0	140732.0	65544.0	102709.0	74743.0	79788.0	115957.0	76075.0	66604.0	54636.0	68661.0	50879.0	81816.0	78629.0	62478.0	72140.0	109576.0	78963.0	45162.0	70728.0	73396.0	83173.0	87607.0	83835.0	145932.0	119638.0	117857.0
Metabolism|Metabolism of Terpenoids and Polyketides|Tetracycline biosynthesis	14512.0	15755.0	10935.0	10853.0	18040.0	15324.0	17398.0	20067.0	17234.0	10169.0	17224.0	18834.0	19005.0	24477.0	17855.0	15056.0	18340.0	19589.0	13265.0	16721.0	21855.0	19562.0	32413.0	20301.0	21288.0	30849.0	22336.0	10716.0	11116.0	17203.0	11877.0	12711.0	33297.0	27123.0	27660.0	27429.0	21244.0	24995.0	20934.0	16365.0	32939.0	13184.0	19333.0	15651.0	17097.0	28249.0	11286.0	12180.0	9348.0	11381.0	8165.0	19940.0	15736.0	12212.0	19716.0	27712.0	18254.0	9824.0	16857.0	15091.0	16142.0	30034.0	28403.0	34600.0	24689.0	22067.0
Metabolism|Metabolism of Terpenoids and Polyketides|Zeatin biosynthesis	10145.0	11229.0	8787.0	7992.0	5345.0	6918.0	7976.0	8822.0	7745.0	6755.0	8692.0	9422.0	9674.0	10722.0	7906.0	7198.0	9289.0	10466.0	6260.0	8260.0	9839.0	8276.0	10030.0	8335.0	8364.0	15118.0	9576.0	6340.0	7993.0	10554.0	7623.0	8170.0	11706.0	9991.0	9409.0	9323.0	8329.0	13131.0	11163.0	8806.0	14430.0	7137.0	8746.0	6354.0	6774.0	9686.0	6794.0	6029.0	4976.0	6192.0	4469.0	8375.0	8178.0	6677.0	6823.0	10743.0	8453.0	4850.0	7528.0	7373.0	8609.0	6478.0	6086.0	11641.0	9486.0	9387.0
Metabolism|Nucleotide Metabolism|Purine metabolism	391637.0	447616.0	349898.0	311928.0	220969.0	380070.0	443740.0	487443.0	426072.0	370267.0	343924.0	367551.0	377678.0	450589.0	336980.0	289268.0	360691.0	398086.0	248081.0	323385.0	412781.0	350165.0	581906.0	369992.0	361823.0	584326.0	408942.0	248614.0	310453.0	418733.0	324829.0	338067.0	561962.0	467384.0	445942.0	457402.0	333302.0	583569.0	489733.0	423646.0	743319.0	301211.0	509755.0	368041.0	400723.0	617792.0	355141.0	311746.0	251761.0	308718.0	227858.0	361780.0	338999.0	275627.0	300724.0	451946.0	347079.0	198435.0	307651.0	318786.0	359725.0	404730.0	384279.0	640548.0	537246.0	499542.0
Metabolism|Nucleotide Metabolism|Pyrimidine metabolism	301306.0	339602.0	272611.0	243340.0	184536.0	286634.0	327477.0	366127.0	318066.0	274460.0	265183.0	282867.0	289403.0	343034.0	258178.0	214279.0	272600.0	303046.0	186000.0	241339.0	304888.0	270149.0	432296.0	274473.0	264826.0	459124.0	312569.0	194571.0	243949.0	330884.0	253191.0	258731.0	442666.0	360843.0	349527.0	357182.0	266861.0	455028.0	372607.0	315844.0	546286.0	228023.0	377162.0	274875.0	296438.0	453903.0	270615.0	238308.0	191944.0	238873.0	174853.0	282417.0	266947.0	214885.0	242826.0	358644.0	265100.0	151816.0	235636.0	243068.0	278895.0	297332.0	278013.0	483113.0	393894.0	383441.0
Metabolism|Xenobiotics Biodegradation and Metabolism|1,1,1-Trichloro-2,2-bis(4-chlorophenyl)ethane (DDT) degradation	0.0	0.0	0.0	0.0	0.0	20.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	21.0	1.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	3.0	0.0	0.0	1.0	10.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Metabolism|Xenobiotics Biodegradation and Metabolism|Aminobenzoate degradation	23316.0	26770.0	19215.0	17553.0	17170.0	19887.0	25607.0	28970.0	24582.0	16512.0	18056.0	18805.0	18716.0	25922.0	18867.0	18078.0	21312.0	22929.0	15563.0	19640.0	23850.0	17662.0	31999.0	26743.0	28076.0	34825.0	26052.0	13757.0	19466.0	22555.0	18449.0	15505.0	26745.0	22107.0	21575.0	21498.0	18324.0	27333.0	25300.0	20643.0	34995.0	14625.0	22994.0	16330.0	18636.0	27977.0	12729.0	13212.0	10675.0	13556.0	10407.0	20899.0	22200.0	15877.0	14248.0	20438.0	20513.0	11032.0	18648.0	19478.0	19148.0	32139.0	30829.0	37297.0	30028.0	24637.0
Metabolism|Xenobiotics Biodegradation and Metabolism|Atrazine degradation	19.0	17.0	14.0	8.0	1173.0	327.0	51.0	23.0	27.0	22.0	525.0	38.0	186.0	592.0	1078.0	105.0	25.0	19.0	3.0	12.0	3055.0	687.0	12006.0	9816.0	12107.0	2856.0	7871.0	590.0	777.0	494.0	867.0	21.0	663.0	1946.0	232.0	447.0	683.0	10204.0	8668.0	6728.0	14348.0	1206.0	8244.0	5534.0	7344.0	13567.0	51.0	122.0	44.0	114.0	198.0	485.0	1027.0	669.0	504.0	1226.0	138.0	117.0	1385.0	937.0	122.0	5279.0	5706.0	1185.0	70.0	675.0
Metabolism|Xenobiotics Biodegradation and Metabolism|Benzoate degradation	22135.0	25581.0	22011.0	18916.0	23787.0	28559.0	28734.0	33859.0	28385.0	21453.0	22253.0	23752.0	23850.0	34106.0	27654.0	18485.0	25285.0	28104.0	17060.0	21728.0	35650.0	30534.0	66968.0	29255.0	25401.0	45031.0	36745.0	17527.0	19976.0	25825.0	20727.0	20502.0	50316.0	43855.0	41410.0	39532.0	26786.0	53036.0	43691.0	39296.0	74791.0	23496.0	47003.0	34466.0	40682.0	67078.0	17786.0	18616.0	13689.0	20048.0	15220.0	29037.0	26708.0	20309.0	27867.0	38525.0	26300.0	14998.0	25644.0	27889.0	28457.0	48429.0	48301.0	55005.0	42176.0	40806.0
Metabolism|Xenobiotics Biodegradation and Metabolism|Bisphenol degradation	12804.0	13669.0	10457.0	10411.0	8048.0	6935.0	10383.0	13538.0	11052.0	7208.0	11941.0	13155.0	13258.0	14329.0	9671.0	2342.0	2432.0	2623.0	3297.0	2287.0	1600.0	6378.0	11098.0	16811.0	17121.0	26164.0	15818.0	7030.0	8816.0	12696.0	8522.0	9621.0	16585.0	10464.0	13401.0	13694.0	7414.0	12518.0	10525.0	7859.0	12362.0	8332.0	6708.0	5177.0	5298.0	7001.0	6335.0	5044.0	4269.0	5602.0	4272.0	9721.0	10988.0	8876.0	11527.0	15135.0	12505.0	7217.0	10589.0	10262.0	11594.0	6711.0	7274.0	13502.0	10433.0	12310.0
Metabolism|Xenobiotics Biodegradation and Metabolism|Caprolactam degradation	6676.0	9120.0	5986.0	4900.0	142.0	10635.0	15751.0	14381.0	13388.0	10892.0	5637.0	5876.0	6409.0	8211.0	4840.0	5368.0	5329.0	5189.0	3893.0	6687.0	12178.0	4463.0	37050.0	12330.0	11680.0	8428.0	14194.0	2693.0	2867.0	4386.0	4184.0	5321.0	7286.0	6042.0	7752.0	9021.0	3118.0	29567.0	25135.0	20939.0	44836.0	7329.0	24695.0	16473.0	21908.0	41742.0	5403.0	6007.0	5067.0	4518.0	3871.0	6937.0	5064.0	4599.0	4114.0	8015.0	5844.0	3180.0	4256.0	4966.0	6101.0	20097.0	21270.0	19813.0	13093.0	8168.0
Metabolism|Xenobiotics Biodegradation and Metabolism|Chloroalkane and chloroalkene degradation	31567.0	36014.0	27304.0	24964.0	16542.0	28184.0	36941.0	43920.0	36890.0	31203.0	25979.0	26971.0	27078.0	34422.0	27045.0	10473.0	13085.0	14398.0	10979.0	10980.0	19007.0	23361.0	44620.0	33183.0	32187.0	48017.0	33805.0	17304.0	21513.0	30863.0	24239.0	26214.0	50643.0	37763.0	37862.0	39840.0	20094.0	47140.0	38201.0	34795.0	58498.0	23350.0	43432.0	31029.0	34968.0	53939.0	27645.0	23114.0	17785.0	22673.0	17014.0	26933.0	29112.0	23189.0	26050.0	34382.0	27138.0	15637.0	24155.0	26065.0	26778.0	31265.0	31184.0	50688.0	42888.0	43390.0
Metabolism|Xenobiotics Biodegradation and Metabolism|Chlorocyclohexane and chlorobenzene degradation	753.0	1309.0	776.0	953.0	1245.0	1045.0	1794.0	3082.0	2084.0	1168.0	976.0	1201.0	1264.0	2216.0	2105.0	1628.0	1801.0	1911.0	1561.0	1621.0	3236.0	2355.0	4737.0	4322.0	5048.0	1887.0	3410.0	486.0	788.0	934.0	1052.0	790.0	2547.0	4956.0	2673.0	2240.0	694.0	4101.0	3326.0	2988.0	5220.0	1393.0	3948.0	2647.0	3241.0	5208.0	483.0	511.0	351.0	443.0	482.0	1618.0	2134.0	1125.0	882.0	2188.0	1612.0	823.0	1195.0	1714.0	626.0	3352.0	3287.0	2374.0	3377.0	2695.0
Metabolism|Xenobiotics Biodegradation and Metabolism|Dioxin degradation	8177.0	10054.0	9670.0	8087.0	6477.0	13809.0	15681.0	17220.0	14979.0	14165.0	11255.0	12064.0	12389.0	16059.0	12751.0	4872.0	7337.0	8132.0	4823.0	5964.0	10163.0	8564.0	22814.0	9727.0	7287.0	17501.0	11740.0	6363.0	6650.0	9626.0	8193.0	11391.0	20172.0	15061.0	14176.0	14713.0	8108.0	18082.0	14818.0	15658.0	31919.0	11192.0	22271.0	15889.0	17774.0	27929.0	13323.0	11995.0	8660.0	11481.0	8234.0	11060.0	10248.0	9046.0	10828.0	15175.0	11183.0	6452.0	10594.0	11055.0	11994.0	17377.0	16618.0	23478.0	21153.0	18830.0
Metabolism|Xenobiotics Biodegradation and Metabolism|Drug metabolism - cytochrome P450	12276.0	14770.0	9703.0	8512.0	3937.0	10756.0	13485.0	14503.0	12600.0	11032.0	8044.0	7764.0	7989.0	11486.0	8842.0	6033.0	6294.0	6598.0	5283.0	6007.0	11779.0	6851.0	26175.0	11042.0	10973.0	10958.0	12635.0	4842.0	6680.0	9261.0	7788.0	8030.0	11294.0	12580.0	8469.0	9896.0	3801.0	28950.0	23702.0	19771.0	36746.0	9163.0	22939.0	14981.0	18559.0	31590.0	7603.0	7057.0	6035.0	6284.0	5060.0	9197.0	9441.0	7850.0	4589.0	7675.0	8982.0	4983.0	7272.0	8393.0	8138.0	16605.0	16094.0	16217.0	15545.0	12482.0
Metabolism|Xenobiotics Biodegradation and Metabolism|Drug metabolism - other enzymes	51327.0	56703.0	45154.0	41041.0	29985.0	42205.0	46436.0	52399.0	45336.0	39637.0	45605.0	49580.0	51089.0	57514.0	42745.0	36432.0	47023.0	52548.0	31681.0	42424.0	52750.0	46018.0	75538.0	46901.0	43468.0	83150.0	56134.0	32964.0	40316.0	56654.0	41008.0	42324.0	66269.0	59049.0	56702.0	55821.0	46013.0	70137.0	63118.0	52108.0	90031.0	37699.0	56588.0	42654.0	46568.0	71946.0	39301.0	34977.0	28117.0	34401.0	25399.0	49260.0	45409.0	36268.0	40019.0	60874.0	44035.0	25245.0	40554.0	39317.0	46386.0	45738.0	41648.0	71737.0	56629.0	56450.0
Metabolism|Xenobiotics Biodegradation and Metabolism|Ethylbenzene degradation	8519.0	9234.0	6210.0	6029.0	8155.0	3506.0	4243.0	6185.0	4726.0	2836.0	4929.0	5696.0	5400.0	8274.0	6865.0	6276.0	7751.0	8428.0	5834.0	7040.0	10886.0	6343.0	16185.0	7577.0	6762.0	12032.0	10168.0	4513.0	6841.0	7986.0	5929.0	3964.0	6704.0	6196.0	5630.0	5217.0	7299.0	15123.0	13814.0	10119.0	18570.0	4400.0	9929.0	6609.0	8180.0	14891.0	1190.0	1784.0	1910.0	2821.0	2232.0	6987.0	7636.0	5004.0	4769.0	5859.0	5846.0	3120.0	5963.0	5383.0	4525.0	10077.0	10213.0	8379.0	7732.0	6416.0
Metabolism|Xenobiotics Biodegradation and Metabolism|Fluorobenzoate degradation	379.0	538.0	303.0	272.0	5.0	643.0	849.0	807.0	713.0	762.0	303.0	364.0	387.0	626.0	436.0	316.0	298.0	318.0	236.0	598.0	1296.0	313.0	4433.0	3693.0	4531.0	1232.0	2771.0	165.0	160.0	271.0	237.0	365.0	351.0	1403.0	475.0	552.0	174.0	3515.0	2972.0	2367.0	5016.0	701.0	3202.0	2293.0	2961.0	4732.0	362.0	270.0	252.0	214.0	187.0	333.0	620.0	550.0	220.0	518.0	236.0	136.0	192.0	182.0	238.0	2007.0	2023.0	944.0	721.0	468.0
Metabolism|Xenobiotics Biodegradation and Metabolism|Metabolism of xenobiotics by cytochrome P450	12275.0	14769.0	9703.0	8512.0	3936.0	10732.0	13482.0	14502.0	12598.0	11030.0	8035.0	7763.0	7986.0	11480.0	8843.0	6031.0	6293.0	6597.0	5283.0	6007.0	11785.0	6846.0	26201.0	9526.0	8833.0	10709.0	11857.0	4842.0	6679.0	9261.0	7788.0	8026.0	11282.0	12578.0	8463.0	9889.0	3796.0	28958.0	23707.0	19775.0	36758.0	9165.0	22948.0	14791.0	18269.0	31116.0	7600.0	7052.0	6033.0	6279.0	5042.0	9186.0	9448.0	7852.0	4548.0	7676.0	8979.0	4983.0	7271.0	8391.0	8137.0	16388.0	15906.0	16195.0	15543.0	12425.0
Metabolism|Xenobiotics Biodegradation and Metabolism|Naphthalene degradation	31127.0	35350.0	25573.0	23199.0	18179.0	21913.0	27123.0	31996.0	26817.0	22066.0	22296.0	23273.0	23068.0	30780.0	23677.0	18624.0	23032.0	25579.0	17328.0	20243.0	28075.0	22947.0	35621.0	28974.0	29191.0	40888.0	29493.0	15948.0	21816.0	28429.0	22334.0	21333.0	36690.0	30386.0	27946.0	27737.0	22147.0	38103.0	34144.0	29702.0	48582.0	19830.0	32476.0	21696.0	24390.0	37812.0	17950.0	16920.0	13485.0	17831.0	13229.0	25760.0	26645.0	20581.0	20769.0	25754.0	23917.0	13646.0	23631.0	23962.0	23506.0	27749.0	27265.0	37736.0	32953.0	31189.0
Metabolism|Xenobiotics Biodegradation and Metabolism|Nitrotoluene degradation	5366.0	6852.0	4668.0	3838.0	3237.0	10056.0	13341.0	12475.0	11579.0	8147.0	4419.0	5265.0	5645.0	7372.0	4667.0	3912.0	3917.0	3766.0	2896.0	5337.0	6836.0	8385.0	23848.0	9427.0	9618.0	11638.0	10453.0	4791.0	4414.0	6565.0	5733.0	4382.0	14354.0	11523.0	14599.0	16947.0	8005.0	15358.0	13381.0	10354.0	20679.0	4652.0	13356.0	10453.0	12725.0	22274.0	5866.0	5068.0	4636.0	4145.0	3723.0	6576.0	5882.0	4157.0	7222.0	12643.0	5012.0	2783.0	8766.0	7024.0	5401.0	17147.0	20618.0	23712.0	12072.0	9613.0
Metabolism|Xenobiotics Biodegradation and Metabolism|Polycyclic aromatic hydrocarbon degradation	15156.0	16740.0	12705.0	12128.0	10905.0	12469.0	15205.0	18746.0	15533.0	11016.0	13528.0	14929.0	14913.0	18669.0	15403.0	14106.0	17633.0	19828.0	12745.0	14643.0	17821.0	16857.0	11020.0	15966.0	17089.0	25957.0	15644.0	11310.0	13857.0	18660.0	13696.0	13016.0	31024.0	22857.0	21936.0	21055.0	17792.0	13336.0	12397.0	11730.0	16152.0	10964.0	13401.0	9319.0	9522.0	11680.0	10972.0	11002.0	7905.0	12267.0	8188.0	15204.0	15631.0	11729.0	15337.0	20692.0	16099.0	8971.0	13901.0	14608.0	13874.0	16560.0	15771.0	26788.0	20634.0	21198.0
Metabolism|Xenobiotics Biodegradation and Metabolism|Styrene degradation	241.0	268.0	141.0	316.0	1859.0	1975.0	3127.0	3689.0	3033.0	451.0	301.0	265.0	181.0	1475.0	1826.0	314.0	422.0	382.0	516.0	109.0	1807.0	1264.0	7156.0	5306.0	5793.0	2652.0	4328.0	344.0	648.0	696.0	1105.0	253.0	3881.0	2071.0	2544.0	2378.0	1104.0	4153.0	3487.0	3083.0	5305.0	902.0	4886.0	3468.0	4460.0	6107.0	140.0	314.0	575.0	833.0	727.0	803.0	2750.0	1482.0	966.0	1793.0	1854.0	962.0	1388.0	2275.0	2604.0	8233.0	8353.0	6605.0	3639.0	3011.0
Metabolism|Xenobiotics Biodegradation and Metabolism|Toluene degradation	23335.0	28272.0	21338.0	18531.0	8235.0	24679.0	41438.0	40077.0	36793.0	24997.0	20135.0	21269.0	22204.0	25992.0	17064.0	18871.0	21452.0	23246.0	15388.0	21257.0	27321.0	17489.0	54124.0	25267.0	23719.0	31439.0	28188.0	12510.0	17422.0	21885.0	19434.0	19417.0	31894.0	21341.0	24799.0	26849.0	14944.0	53818.0	42784.0	34802.0	65645.0	19446.0	44293.0	29865.0	36150.0	58457.0	19343.0	15808.0	15003.0	14596.0	12043.0	19387.0	21726.0	15976.0	13106.0	23687.0	21173.0	11405.0	16536.0	18504.0	20380.0	40668.0	44891.0	52147.0	30975.0	21526.0
Metabolism|Xenobiotics Biodegradation and Metabolism|Xylene degradation	7710.0	9570.0	8423.0	7052.0	5368.0	11559.0	14729.0	15852.0	13942.0	13580.0	10352.0	11297.0	11448.0	14515.0	10857.0	4348.0	6188.0	6839.0	4172.0	5291.0	7508.0	8346.0	15242.0	8539.0	6833.0	16771.0	9271.0	5984.0	6016.0	8913.0	7356.0	10982.0	19036.0	14647.0	13881.0	14409.0	7913.0	11284.0	9032.0	10674.0	21964.0	9916.0	15636.0	11060.0	12135.0	18398.0	11581.0	10157.0	7472.0	9634.0	7031.0	9746.0	8720.0	8008.0	10217.0	13316.0	10566.0	6228.0	10069.0	10494.0	11288.0	11750.0	11700.0	20590.0	17864.0	16142.0
Organismal Systems|Circulatory System|Cardiac muscle contraction	6.0	24.0	18.0	48.0	0.0	192.0	5.0	3.0	6.0	3.0	3.0	90.0	9.0	39.0	10.0	0.0	0.0	6.0	9.0	0.0	0.0	0.0	3.0	0.0	0.0	3.0	4.0	0.0	6.0	0.0	0.0	3.0	0.0	0.0	0.0	0.0	3.0	7200.0	2214.0	0.0	5.0	6.0	21.0	9.0	6.0	3.0	42.0	21.0	378.0	48.0	6.0	0.0	3.0	3.0	0.0	3.0	0.0	0.0	2.0	0.0	0.0	0.0	0.0	3.0	6.0	3.0
Organismal Systems|Circulatory System|Vascular smooth muscle contraction	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Organismal Systems|Digestive System|Bile secretion	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	3.0	0.0	0.0	0.0	0.0	0.0	6.0	0.0	26.0	1.0	1.0	0.0	2.0	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	2.0	0.0	75.0	59.0	40.0	14.0	4.0	18.0	5.0	9.0	9.0	0.0	0.0	0.0	0.0	0.0	0.0	8.0	5.0	0.0	4.0	0.0	0.0	0.0	0.0	0.0	10.0	7.0	2.0	0.0	1.0
Organismal Systems|Digestive System|Carbohydrate digestion and absorption	1033.0	1159.0	782.0	936.0	2525.0	1321.0	1536.0	1805.0	1587.0	1055.0	878.0	1301.0	1154.0	1674.0	1749.0	4999.0	6219.0	7080.0	4383.0	6113.0	8335.0	3918.0	8298.0	1448.0	659.0	1321.0	2643.0	602.0	633.0	966.0	915.0	1178.0	2078.0	3132.0	1986.0	1620.0	4422.0	7279.0	7010.0	4754.0	9773.0	1130.0	6316.0	4512.0	5980.0	10341.0	974.0	1524.0	968.0	1505.0	741.0	1873.0	2929.0	1369.0	1038.0	1973.0	1016.0	649.0	2132.0	1034.0	752.0	3586.0	3521.0	1726.0	1386.0	1358.0
Organismal Systems|Digestive System|Fat digestion and absorption	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Organismal Systems|Digestive System|Gastric acid secretion	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Organismal Systems|Digestive System|Mineral absorption	183.0	161.0	140.0	251.0	1093.0	403.0	449.0	1312.0	849.0	258.0	297.0	221.0	113.0	273.0	143.0	854.0	398.0	402.0	667.0	304.0	9.0	242.0	325.0	323.0	230.0	414.0	232.0	139.0	261.0	171.0	262.0	31.0	714.0	1818.0	331.0	435.0	229.0	137.0	99.0	29.0	49.0	70.0	937.0	985.0	725.0	768.0	957.0	618.0	723.0	717.0	581.0	186.0	775.0	394.0	126.0	50.0	314.0	209.0	323.0	596.0	626.0	369.0	221.0	126.0	81.0	146.0
Organismal Systems|Digestive System|Pancreatic secretion	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Organismal Systems|Digestive System|Protein digestion and absorption	11406.0	12571.0	8784.0	8220.0	3064.0	3026.0	4507.0	4819.0	4277.0	4684.0	9308.0	9930.0	10192.0	10656.0	7285.0	5356.0	7016.0	8015.0	4640.0	6440.0	7608.0	5420.0	3678.0	6036.0	5801.0	14480.0	7422.0	5872.0	8371.0	10325.0	7168.0	8718.0	5108.0	4784.0	3890.0	3604.0	5609.0	9135.0	10067.0	7632.0	11987.0	7691.0	4360.0	2882.0	2994.0	3204.0	4418.0	3375.0	2998.0	3523.0	2563.0	7181.0	8134.0	6924.0	3917.0	7259.0	8488.0	4878.0	6786.0	6288.0	8157.0	2.0	4.0	4012.0	4139.0	3903.0
Organismal Systems|Digestive System|Salivary secretion	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Organismal Systems|Endocrine System|Adipocytokine signaling pathway	23772.0	27496.0	19262.0	17454.0	8280.0	15102.0	20287.0	21325.0	19320.0	20775.0	19248.0	20700.0	21412.0	21720.0	15241.0	15826.0	18690.0	21206.0	12870.0	17166.0	19265.0	17152.0	13031.0	15479.0	14864.0	30688.0	16011.0	13847.0	18064.0	22248.0	17253.0	21099.0	20860.0	18696.0	15497.0	15988.0	15669.0	19193.0	17972.0	16269.0	24433.0	16133.0	18238.0	12380.0	11780.0	13790.0	20367.0	15114.0	13133.0	15559.0	11657.0	15334.0	16892.0	14387.0	10199.0	18916.0	16724.0	10107.0	14231.0	15234.0	18672.0	1869.0	974.0	18147.0	18588.0	18058.0
Organismal Systems|Endocrine System|GnRH signaling pathway	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0
Organismal Systems|Endocrine System|Insulin signaling pathway	15609.0	16821.0	11587.0	11107.0	10160.0	10523.0	10669.0	13014.0	11016.0	9088.0	12349.0	13898.0	14185.0	16043.0	11825.0	10776.0	12977.0	14305.0	9765.0	12090.0	15998.0	12721.0	19403.0	14843.0	15348.0	22178.0	16810.0	8831.0	10552.0	14770.0	10137.0	10954.0	16198.0	18003.0	14400.0	14740.0	12342.0	19777.0	18399.0	15049.0	27614.0	10656.0	15783.0	11729.0	12587.0	20034.0	9855.0	8501.0	6863.0	8384.0	6175.0	12471.0	12146.0	10344.0	9592.0	15895.0	11093.0	6406.0	10659.0	8792.0	11570.0	11856.0	9715.0	14553.0	14217.0	14577.0
Organismal Systems|Endocrine System|Melanogenesis	0.0	0.0	0.0	0.0	0.0	10.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Organismal Systems|Endocrine System|PPAR signaling pathway	28540.0	32632.0	22902.0	20799.0	13163.0	18455.0	24152.0	26190.0	23308.0	22974.0	22994.0	24977.0	25610.0	28442.0	20553.0	17841.0	20836.0	23282.0	14747.0	18670.0	21924.0	20087.0	20074.0	22096.0	22306.0	39190.0	22590.0	16801.0	21554.0	27215.0	20698.0	24023.0	27262.0	24987.0	20521.0	21796.0	18705.0	27632.0	24495.0	20662.0	32826.0	19339.0	23224.0	16128.0	15861.0	20171.0	22524.0	17434.0	14785.0	17695.0	13254.0	19798.0	22005.0	18336.0	13835.0	25269.0	21310.0	12392.0	18401.0	18962.0	22462.0	10359.0	9255.0	27050.0	25920.0	24594.0
Organismal Systems|Endocrine System|Progesterone-mediated oocyte maturation	4828.0	5222.0	3539.0	3519.0	3116.0	1901.0	3193.0	3255.0	2980.0	2035.0	3988.0	4935.0	5202.0	4877.0	3154.0	5384.0	6846.0	7652.0	4404.0	6795.0	7749.0	6216.0	8064.0	5390.0	5523.0	8453.0	6210.0	3617.0	4068.0	5773.0	3824.0	3209.0	6516.0	7200.0	7065.0	6751.0	6731.0	9083.0	7073.0	4341.0	8101.0	3058.0	3241.0	2597.0	3377.0	5959.0	923.0	1051.0	1214.0	1100.0	925.0	3952.0	3251.0	2797.0	4137.0	6605.0	3474.0	1964.0	3851.0	3094.0	3325.0	3854.0	4448.0	5784.0	2682.0	3185.0
Organismal Systems|Endocrine System|Renin-angiotensin system	0.0	0.0	0.0	0.0	0.0	9.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	5.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Organismal Systems|Environmental Adaptation|Circadian rhythm - plant	1.0	1.0	0.0	0.0	1.0	2.0	0.0	0.0	1.0	0.0	3.0	0.0	1.0	1.0	2.0	1.0	1.0	1.0	0.0	0.0	0.0	0.0	0.0	1516.0	2140.0	245.0	779.0	0.0	0.0	0.0	0.0	3.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	0.0	3.0	2.0	1.0	0.0	2.0	2.0	0.0	1.0	1.0	1.0	0.0	0.0	0.0	1.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0
Organismal Systems|Environmental Adaptation|Plant-pathogen interaction	18817.0	20223.0	15015.0	13787.0	15128.0	14817.0	18237.0	20879.0	17815.0	13298.0	15194.0	17942.0	17998.0	21633.0	16063.0	13735.0	16323.0	17763.0	12012.0	15199.0	19947.0	18584.0	33834.0	19043.0	18647.0	31005.0	22893.0	13565.0	14826.0	21405.0	14548.0	13281.0	29615.0	25574.0	24939.0	26068.0	18068.0	34688.0	27331.0	20254.0	37876.0	13029.0	23536.0	18013.0	20398.0	33517.0	11806.0	10761.0	9218.0	10527.0	8054.0	17102.0	17091.0	13400.0	15465.0	26558.0	15041.0	8283.0	14771.0	13724.0	14885.0	22934.0	23208.0	31182.0	22450.0	25092.0
Organismal Systems|Excretory System|Aldosterone-regulated sodium reabsorption	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Organismal Systems|Excretory System|Endocrine and other factor-regulated calcium reabsorption	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Organismal Systems|Excretory System|Proximal tubule bicarbonate reclamation	7642.0	8368.0	6357.0	5563.0	3294.0	2572.0	2482.0	2222.0	2272.0	2236.0	5869.0	6203.0	6429.0	6887.0	4128.0	4513.0	5267.0	5841.0	3495.0	4992.0	4831.0	2940.0	7959.0	8517.0	10132.0	10011.0	8288.0	3099.0	4441.0	5960.0	4177.0	4465.0	1476.0	2959.0	2167.0	2060.0	3065.0	8138.0	8191.0	6042.0	11242.0	4979.0	3184.0	2490.0	3066.0	5417.0	1025.0	1035.0	931.0	1005.0	883.0	5157.0	4442.0	4182.0	2282.0	4114.0	5509.0	3148.0	4733.0	3951.0	5464.0	2979.0	3076.0	4536.0	2683.0	1972.0
Organismal Systems|Excretory System|Vasopressin-regulated water reabsorption	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Organismal Systems|Immune System|Antigen processing and presentation	4828.0	5222.0	3539.0	3519.0	3116.0	1901.0	3193.0	3255.0	2980.0	2035.0	3988.0	4935.0	5202.0	4877.0	3154.0	5384.0	6846.0	7652.0	4404.0	6795.0	7749.0	6216.0	8064.0	5390.0	5523.0	8453.0	6210.0	3617.0	4068.0	5773.0	3824.0	3209.0	6516.0	7200.0	7065.0	6751.0	6731.0	9083.0	7073.0	4341.0	8101.0	3058.0	3241.0	2597.0	3377.0	5959.0	923.0	1051.0	1214.0	1100.0	925.0	3952.0	3251.0	2797.0	4137.0	6605.0	3474.0	1964.0	3851.0	3094.0	3325.0	3854.0	4448.0	5784.0	2682.0	3185.0
Organismal Systems|Immune System|Complement and coagulation cascades	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Organismal Systems|Immune System|Cytosolic DNA-sensing pathway	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Organismal Systems|Immune System|Fc epsilon RI signaling pathway	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Organismal Systems|Immune System|Fc gamma R-mediated phagocytosis	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0
Organismal Systems|Immune System|Hematopoietic cell lineage	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Organismal Systems|Immune System|Leukocyte transendothelial migration	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Organismal Systems|Immune System|NOD-like receptor signaling pathway	7894.0	8407.0	5551.0	5299.0	3144.0	2751.0	3207.0	3256.0	2992.0	2054.0	6341.0	7122.0	7357.0	7376.0	4765.0	5409.0	6853.0	7666.0	4467.0	6795.0	7750.0	6227.0	8298.0	6382.0	6607.0	11238.0	7620.0	4393.0	5185.0	7647.0	4858.0	4801.0	6679.0	7226.0	7076.0	6759.0	6769.0	11535.0	9843.0	6254.0	10998.0	4912.0	3381.0	2939.0	3915.0	6479.0	933.0	1073.0	1222.0	1176.0	1129.0	5858.0	5261.0	4520.0	4873.0	7791.0	5553.0	3069.0	5263.0	4333.0	5411.0	4465.0	4493.0	6035.0	2710.0	3410.0
Organismal Systems|Immune System|RIG-I-like receptor signaling pathway	6.0	4.0	7.0	2.0	2.0	930.0	25.0	7.0	9.0	13.0	202.0	64.0	17.0	181.0	304.0	9.0	9.0	8.0	7.0	5.0	961.0	80.0	3218.0	403.0	139.0	137.0	1073.0	43.0	29.0	31.0	3.0	5.0	409.0	184.0	136.0	191.0	139.0	3285.0	2732.0	2410.0	4906.0	482.0	2678.0	1649.0	2231.0	4462.0	33.0	41.0	29.0	119.0	224.0	922.0	100.0	69.0	353.0	1087.0	4.0	1.0	48.0	15.0	348.0	2201.0	1574.0	531.0	24.0	304.0
Organismal Systems|Nervous System|Cholinergic synapse	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Organismal Systems|Nervous System|Glutamatergic synapse	23451.0	25728.0	19461.0	17809.0	10851.0	12237.0	15746.0	17785.0	15534.0	13662.0	19235.0	21277.0	21858.0	23734.0	17140.0	14827.0	19005.0	21327.0	12585.0	17041.0	19838.0	18165.0	22192.0	19782.0	20720.0	34882.0	22083.0	14042.0	16944.0	23226.0	15907.0	17638.0	25907.0	23005.0	21406.0	21560.0	18176.0	28325.0	24471.0	18864.0	31556.0	15905.0	16087.0	11729.0	12982.0	19555.0	12116.0	10077.0	8287.0	9948.0	7443.0	17926.0	17117.0	14620.0	14490.0	23839.0	18485.0	10561.0	15744.0	15032.0	18584.0	12653.0	12480.0	22858.0	18716.0	18366.0
Organismal Systems|Nervous System|Long-term depression	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Organismal Systems|Nervous System|Long-term potentiation	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Organismal Systems|Nervous System|Neurotrophin signaling pathway	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Organismal Systems|Sensory System|Olfactory transduction	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Organismal Systems|Sensory System|Phototransduction	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Organismal Systems|Sensory System|Phototransduction - fly	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Unclassified|Cellular Processes and Signaling|Cell division	15819.0	17679.0	12531.0	11473.0	8098.0	10667.0	12263.0	12823.0	11492.0	10398.0	12888.0	14386.0	14748.0	16370.0	11622.0	11098.0	13385.0	14715.0	9269.0	13018.0	16942.0	12400.0	22890.0	11630.0	11744.0	22503.0	15827.0	10513.0	13704.0	17566.0	12405.0	11628.0	15821.0	15138.0	14107.0	14883.0	12695.0	25461.0	22492.0	17251.0	32042.0	11239.0	17521.0	12877.0	14371.0	23628.0	9864.0	7610.0	7427.0	7375.0	6018.0	11758.0	11910.0	10161.0	9341.0	15777.0	12138.0	6942.0	11358.0	10574.0	12351.0	12399.0	12749.0	16723.0	13598.0	11671.0
Unclassified|Cellular Processes and Signaling|Cell motility and secretion	37902.0	42471.0	34240.0	29947.0	17561.0	31489.0	35682.0	38081.0	33508.0	29101.0	28695.0	31548.0	32756.0	36494.0	23741.0	23225.0	29496.0	32398.0	20804.0	28629.0	35189.0	24226.0	66495.0	50544.0	55107.0	53704.0	48050.0	21184.0	27633.0	35262.0	27531.0	26213.0	27831.0	28660.0	26008.0	28500.0	23711.0	65349.0	54244.0	41592.0	78678.0	25087.0	47043.0	35019.0	39030.0	63468.0	26741.0	23233.0	20690.0	23077.0	18036.0	28232.0	26474.0	22607.0	18122.0	32596.0	27403.0	16396.0	27644.0	25262.0	29694.0	32343.0	32299.0	46045.0	38508.0	32606.0
Unclassified|Cellular Processes and Signaling|Electron transfer carriers	5692.0	7328.0	4693.0	4017.0	1038.0	10700.0	25948.0	23195.0	22079.0	9290.0	4283.0	4716.0	5101.0	6177.0	4488.0	4336.0	4237.0	4112.0	3067.0	5713.0	9639.0	5491.0	33408.0	7001.0	3205.0	8334.0	9784.0	2938.0	3682.0	4555.0	6099.0	4466.0	20205.0	9068.0	15310.0	16305.0	3507.0	23563.0	20177.0	17586.0	34960.0	6450.0	24469.0	15831.0	21843.0	38064.0	4948.0	5885.0	4559.0	4854.0	3396.0	5218.0	5840.0	3430.0	4811.0	15022.0	7768.0	3612.0	6465.0	8093.0	6824.0	39146.0	46669.0	44343.0	13760.0	7655.0
Unclassified|Cellular Processes and Signaling|Germination	342.0	126.0	93.0	102.0	2061.0	313.0	80.0	13.0	123.0	12.0	182.0	707.0	708.0	543.0	540.0	33.0	4.0	6.0	1.0	0.0	97.0	2408.0	1935.0	1477.0	1670.0	3233.0	1883.0	1543.0	558.0	1780.0	13.0	30.0	5242.0	4749.0	4219.0	4771.0	2251.0	9.0	0.0	14.0	4.0	12.0	23.0	12.0	14.0	33.0	9.0	30.0	8.0	33.0	61.0	1151.0	738.0	695.0	2193.0	4870.0	20.0	0.0	4.0	8.0	54.0	287.0	202.0	112.0	82.0	2497.0
Unclassified|Cellular Processes and Signaling|Inorganic ion transport and metabolism	58551.0	69653.0	48935.0	44477.0	16067.0	48529.0	69450.0	73699.0	64878.0	58745.0	48142.0	53069.0	54869.0	61001.0	42317.0	43311.0	50705.0	54780.0	35709.0	51919.0	71182.0	40783.0	134982.0	66852.0	64677.0	83650.0	73439.0	30745.0	37970.0	52419.0	43049.0	46412.0	54686.0	46920.0	48757.0	51725.0	43114.0	121729.0	107584.0	86432.0	171097.0	44501.0	102987.0	72433.0	88161.0	150598.0	45176.0	38676.0	34464.0	34828.0	26998.0	44801.0	44335.0	37998.0	32787.0	49655.0	43805.0	25655.0	44313.0	40868.0	45501.0	67405.0	70635.0	83121.0	67712.0	56131.0
Unclassified|Cellular Processes and Signaling|Membrane and intracellular structural molecules	154271.0	171568.0	120789.0	110979.0	53132.0	82617.0	95950.0	97500.0	88161.0	79495.0	122461.0	135297.0	141157.0	150554.0	101006.0	99390.0	121510.0	133227.0	84801.0	121539.0	160327.0	93466.0	258211.0	131430.0	129536.0	203360.0	164458.0	81222.0	106079.0	141642.0	101784.0	103375.0	84279.0	95310.0	89193.0	90184.0	92214.0	280931.0	247781.0	181167.0	348006.0	107551.0	168209.0	123333.0	146096.0	250776.0	71438.0	63300.0	60966.0	59951.0	47360.0	113683.0	102616.0	88829.0	66780.0	122637.0	114782.0	66039.0	106435.0	93473.0	112373.0	115504.0	112755.0	122681.0	103157.0	82788.0
Unclassified|Cellular Processes and Signaling|Other ion-coupled transporters	253267.0	286064.0	216763.0	195923.0	126525.0	191189.0	247934.0	261255.0	232037.0	196998.0	221265.0	240562.0	249709.0	280789.0	201757.0	189800.0	231453.0	253743.0	158777.0	222035.0	298616.0	214452.0	517538.0	245916.0	223933.0	388444.0	303430.0	149570.0	181155.0	247830.0	184247.0	195765.0	292021.0	261507.0	262030.0	263212.0	202465.0	474079.0	419759.0	335505.0	634130.0	195831.0	371625.0	271291.0	318123.0	529529.0	174675.0	149403.0	129389.0	143867.0	111893.0	215927.0	206988.0	169582.0	175536.0	279157.0	217788.0	125500.0	204859.0	194427.0	215455.0	281058.0	293046.0	357374.0	276387.0	244997.0
Unclassified|Cellular Processes and Signaling|Other transporters	45013.0	50369.0	37026.0	34602.0	30901.0	33839.0	45138.0	48995.0	43057.0	33453.0	38556.0	43818.0	45740.0	51474.0	35737.0	34245.0	42043.0	45793.0	30030.0	41137.0	53763.0	40007.0	93293.0	44891.0	42151.0	70605.0	55212.0	27726.0	32263.0	44504.0	33039.0	34413.0	53177.0	50211.0	50343.0	50909.0	41200.0	80878.0	71188.0	54101.0	106234.0	33401.0	60198.0	44401.0	51135.0	87294.0	28682.0	24125.0	22448.0	22134.0	17854.0	38226.0	37759.0	30670.0	34121.0	50940.0	38900.0	22594.0	40131.0	35073.0	39848.0	53041.0	55406.0	69806.0	48145.0	43032.0
Unclassified|Cellular Processes and Signaling|Pores ion channels	107539.0	119184.0	84189.0	77115.0	40752.0	56480.0	65494.0	64076.0	59151.0	54567.0	89990.0	99784.0	104188.0	111440.0	76116.0	75413.0	93297.0	102652.0	63545.0	92635.0	127273.0	69401.0	198399.0	91382.0	87553.0	145147.0	121324.0	55564.0	71459.0	94443.0	67329.0	75420.0	55205.0	71774.0	60050.0	61457.0	68027.0	195696.0	184699.0	140167.0	276672.0	81756.0	133118.0	97481.0	116060.0	200626.0	50589.0	43442.0	43858.0	41468.0	32909.0	78933.0	74699.0	65105.0	45020.0	88541.0	84727.0	48519.0	76005.0	66540.0	81323.0	85961.0	86584.0	88774.0	72167.0	56385.0
Unclassified|Cellular Processes and Signaling|Signal transduction mechanisms	65117.0	76949.0	64001.0	55839.0	45303.0	76553.0	96324.0	105025.0	91576.0	80644.0	58413.0	64098.0	66004.0	84479.0	64794.0	57923.0	73106.0	79714.0	48481.0	66957.0	93691.0	76517.0	166559.0	83427.0	81926.0	108886.0	91835.0	45337.0	50871.0	73392.0	55718.0	59514.0	125696.0	113326.0	107777.0	108950.0	70933.0	140905.0	117223.0	101690.0	192296.0	56632.0	131860.0	94063.0	107845.0	180200.0	70111.0	61143.0	50465.0	58275.0	44416.0	71423.0	62645.0	49953.0	68317.0	93885.0	59252.0	33339.0	53703.0	55156.0	61826.0	100049.0	99679.0	140804.0	120658.0	105901.0
Unclassified|Cellular Processes and Signaling|Sporulation	14961.0	8146.0	6293.0	8028.0	56546.0	16295.0	13196.0	20242.0	17529.0	9706.0	13159.0	19059.0	17287.0	20713.0	18261.0	2152.0	2413.0	2545.0	1974.0	1439.0	5435.0	55816.0	53206.0	41034.0	43164.0	73791.0	47618.0	23787.0	11842.0	28687.0	11427.0	9053.0	107938.0	93736.0	105350.0	108110.0	55584.0	15057.0	6805.0	7053.0	11358.0	7911.0	10338.0	19912.0	21808.0	43299.0	9713.0	8108.0	5800.0	8690.0	7027.0	31755.0	17861.0	15710.0	71912.0	82352.0	11400.0	7232.0	24784.0	17795.0	18075.0	35140.0	42141.0	73392.0	22913.0	65741.0
Unclassified|Genetic Information Processing|Protein folding and associated processing	118534.0	135867.0	99336.0	89621.0	61237.0	111819.0	135113.0	143901.0	127546.0	112607.0	102810.0	108879.0	112434.0	132644.0	98120.0	80044.0	93139.0	101401.0	66720.0	89536.0	125977.0	89489.0	229773.0	131760.0	131651.0	175854.0	145732.0	74133.0	93917.0	121552.0	96752.0	101770.0	144549.0	122338.0	116364.0	122610.0	91302.0	225587.0	195958.0	158648.0	299513.0	93597.0	191442.0	137374.0	156750.0	255490.0	106973.0	90382.0	76118.0	88511.0	66586.0	100073.0	105693.0	83710.0	81637.0	126284.0	100068.0	57388.0	93313.0	92524.0	105741.0	132746.0	132175.0	183795.0	147417.0	134048.0
Unclassified|Genetic Information Processing|Replication, recombination and repair proteins	129511.0	156412.0	119145.0	105468.0	73530.0	148068.0	188611.0	202673.0	177124.0	161815.0	111763.0	122252.0	127261.0	148723.0	103594.0	87370.0	105760.0	113696.0	74192.0	109044.0	120896.0	112734.0	243480.0	147681.0	146460.0	208602.0	145316.0	82099.0	94885.0	133503.0	105341.0	116970.0	213469.0	178356.0	184988.0	186243.0	121623.0	186859.0	152150.0	132552.0	244850.0	94498.0	175493.0	123019.0	136742.0	216691.0	129406.0	112818.0	95838.0	110634.0	84611.0	120364.0	105147.0	84829.0	126482.0	141522.0	109766.0	63265.0	95143.0	102883.0	119211.0	131288.0	123194.0	238155.0	213390.0	179504.0
Unclassified|Genetic Information Processing|Restriction enzyme	45632.0	49193.0	34143.0	31793.0	13914.0	30127.0	27806.0	28458.0	26030.0	24151.0	44239.0	46226.0	48222.0	48222.0	32857.0	28555.0	38032.0	43015.0	25295.0	34912.0	41963.0	29915.0	36027.0	33912.0	34112.0	68108.0	41390.0	25226.0	32222.0	42136.0	29684.0	36361.0	39180.0	30142.0	29492.0	29067.0	36122.0	40312.0	39044.0	35886.0	65910.0	34780.0	29438.0	21460.0	22225.0	31313.0	24915.0	21790.0	17616.0	24195.0	18041.0	29686.0	26803.0	27025.0	20764.0	40780.0	38278.0	22598.0	31217.0	29774.0	41640.0	24872.0	20260.0	40688.0	32159.0	33242.0
Unclassified|Genetic Information Processing|Transcription related proteins	2799.0	3436.0	2834.0	2043.0	664.0	1800.0	3223.0	3491.0	2929.0	2538.0	1138.0	1406.0	1568.0	2665.0	2265.0	1390.0	2138.0	2224.0	1413.0	2061.0	3350.0	1085.0	8599.0	2974.0	2854.0	2116.0	3269.0	1560.0	1999.0	1952.0	2358.0	1545.0	1809.0	1608.0	1646.0	1861.0	820.0	6988.0	5891.0	4601.0	10014.0	1636.0	6073.0	3985.0	5142.0	9211.0	1093.0	1027.0	977.0	763.0	804.0	1594.0	1867.0	1533.0	1272.0	1995.0	1454.0	773.0	2018.0	2139.0	1414.0	5303.0	5636.0	4380.0	5007.0	3490.0
Unclassified|Genetic Information Processing|Translation proteins	146537.0	166404.0	129690.0	114559.0	92362.0	144112.0	167421.0	182325.0	160365.0	140170.0	119814.0	130179.0	134171.0	158841.0	117106.0	102925.0	126828.0	139197.0	87662.0	116326.0	150263.0	132625.0	245178.0	140654.0	138808.0	212140.0	157300.0	94526.0	115253.0	155610.0	120300.0	119427.0	207044.0	182145.0	175155.0	180452.0	124343.0	232362.0	191005.0	161095.0	286985.0	106477.0	202026.0	147962.0	160296.0	250873.0	137064.0	120209.0	99868.0	118581.0	87789.0	135058.0	122680.0	99490.0	116099.0	168751.0	120678.0	69732.0	110969.0	116159.0	131832.0	151784.0	145903.0	244652.0	197579.0	184816.0
Unclassified|Metabolism|Amino acid metabolism	33171.0	37530.0	27558.0	24593.0	19373.0	22251.0	26411.0	29345.0	25104.0	20983.0	25144.0	27539.0	28192.0	35090.0	25774.0	23073.0	28113.0	30664.0	19972.0	27926.0	35045.0	27143.0	63677.0	37237.0	37204.0	52516.0	41872.0	19916.0	26407.0	33948.0	27233.0	22432.0	30805.0	36664.0	32672.0	31665.0	26347.0	53584.0	48033.0	36013.0	65830.0	22387.0	36843.0	27965.0	32810.0	53711.0	16550.0	16560.0	13278.0	16208.0	12193.0	30988.0	30385.0	22579.0	25415.0	31768.0	26091.0	14956.0	30111.0	26972.0	27100.0	37171.0	38722.0	46358.0	33900.0	31745.0
Unclassified|Metabolism|Biosynthesis and biodegradation of secondary metabolites	12094.0	14376.0	9644.0	8868.0	5683.0	9187.0	12629.0	12509.0	11305.0	9280.0	10009.0	11454.0	11895.0	13628.0	10057.0	11245.0	13474.0	14567.0	9276.0	14260.0	23346.0	10877.0	48211.0	16225.0	14691.0	19554.0	22523.0	7184.0	8794.0	11497.0	8642.0	8365.0	11358.0	12357.0	11628.0	12116.0	10955.0	41754.0	36783.0	28939.0	60296.0	11500.0	32568.0	22679.0	28891.0	51671.0	6497.0	5889.0	5341.0	4802.0	3982.0	9961.0	9582.0	8537.0	6336.0	14320.0	9743.0	5542.0	8760.0	8237.0	9398.0	23402.0	23955.0	16451.0	12896.0	9478.0
Unclassified|Metabolism|Carbohydrate metabolism	33590.0	37516.0	27718.0	27147.0	14985.0	21902.0	26685.0	33344.0	27438.0	24514.0	32951.0	37101.0	37990.0	38628.0	29737.0	16842.0	20857.0	23799.0	16433.0	19639.0	36187.0	30288.0	70043.0	39629.0	36586.0	60769.0	47843.0	18748.0	21161.0	32171.0	21404.0	29040.0	43515.0	42994.0	35181.0	36753.0	21217.0	70675.0	62746.0	55339.0	104104.0	32258.0	58834.0	40685.0	48468.0	82467.0	24256.0	21097.0	15281.0	20817.0	14543.0	32270.0	29165.0	26019.0	25158.0	46579.0	27585.0	16544.0	24116.0	22599.0	29958.0	29393.0	28067.0	31734.0	27974.0	33815.0
Unclassified|Metabolism|Energy metabolism	144146.0	159128.0	114980.0	105684.0	93584.0	96427.0	140024.0	148060.0	131553.0	88341.0	112356.0	128527.0	131903.0	148912.0	106392.0	112347.0	134924.0	148334.0	96357.0	130373.0	170207.0	129658.0	271591.0	136611.0	131788.0	213983.0	170536.0	90443.0	114890.0	151461.0	113991.0	99023.0	172395.0	156171.0	157111.0	159116.0	122549.0	251569.0	221922.0	169489.0	314549.0	102103.0	183214.0	137842.0	159500.0	265549.0	80987.0	68494.0	64686.0	67289.0	53009.0	121798.0	121059.0	93898.0	97658.0	170379.0	118498.0	66497.0	117093.0	109083.0	115708.0	184632.0	201072.0	233087.0	132559.0	125436.0
Unclassified|Metabolism|Glycan biosynthesis and metabolism	10825.0	12756.0	8735.0	7477.0	4732.0	9500.0	12723.0	11759.0	11085.0	10794.0	8148.0	9153.0	9686.0	10759.0	6362.0	7531.0	8268.0	8488.0	5898.0	9633.0	14357.0	6184.0	36640.0	7243.0	4808.0	11801.0	12829.0	5227.0	6714.0	8675.0	7423.0	7348.0	3509.0	6984.0	6542.0	7511.0	5163.0	29403.0	25810.0	20017.0	42970.0	8569.0	23857.0	17610.0	21106.0	38480.0	8607.0	6809.0	7419.0	5564.0	4918.0	8126.0	6140.0	5857.0	3983.0	6979.0	7297.0	4311.0	7379.0	6734.0	7929.0	14112.0	14696.0	15181.0	12289.0	7638.0
Unclassified|Metabolism|Lipid metabolism	17050.0	18460.0	12967.0	12193.0	14387.0	10773.0	12082.0	15565.0	12495.0	6525.0	11624.0	14000.0	13663.0	18159.0	15544.0	13785.0	16332.0	18032.0	12591.0	14996.0	28252.0	16243.0	55450.0	20583.0	19733.0	26025.0	29042.0	9806.0	10475.0	16608.0	10074.0	8655.0	26598.0	22383.0	20232.0	20902.0	16551.0	57775.0	47968.0	37050.0	73433.0	13768.0	41588.0	28809.0	35742.0	64263.0	5958.0	7099.0	5867.0	7183.0	4926.0	16453.0	17559.0	13525.0	13148.0	25295.0	12463.0	6640.0	10366.0	10603.0	12191.0	33174.0	33540.0	24329.0	15329.0	17055.0
Unclassified|Metabolism|Metabolism of cofactors and vitamins	20811.0	23934.0	18054.0	15417.0	13109.0	22331.0	28053.0	28910.0	25946.0	20170.0	18611.0	19439.0	20342.0	25877.0	18947.0	14911.0	17867.0	18792.0	12564.0	17329.0	26619.0	15406.0	62932.0	27492.0	28183.0	30293.0	31192.0	10617.0	13104.0	17820.0	15682.0	16651.0	22408.0	19845.0	19018.0	20793.0	13648.0	47261.0	41735.0	35252.0	72167.0	18120.0	44653.0	33930.0	39517.0	67204.0	20189.0	17549.0	15237.0	16115.0	12518.0	17693.0	16809.0	13678.0	11080.0	20456.0	19755.0	11190.0	19190.0	18861.0	21286.0	41808.0	43840.0	45636.0	32495.0	25123.0
Unclassified|Metabolism|Nucleotide metabolism	8984.0	11468.0	10206.0	8731.0	4937.0	16729.0	21760.0	22664.0	20030.0	18760.0	8781.0	8982.0	9555.0	13515.0	11095.0	5644.0	6850.0	6950.0	4454.0	7321.0	13039.0	5252.0	42756.0	12961.0	8863.0	15163.0	16021.0	5901.0	8114.0	10295.0	10050.0	10721.0	13979.0	7432.0	9674.0	11378.0	7196.0	32231.0	28080.0	24529.0	50535.0	9667.0	35386.0	24525.0	29118.0	49915.0	16206.0	13923.0	11049.0	13214.0	9575.0	8605.0	11276.0	8466.0	6553.0	11192.0	9531.0	5504.0	9792.0	9795.0	10685.0	24050.0	25728.0	30756.0	24335.0	21414.0
Unclassified|Metabolism|Others	172417.0	198178.0	150439.0	139749.0	101402.0	140366.0	185014.0	221894.0	183820.0	147529.0	144676.0	164717.0	165674.0	211920.0	160416.0	134824.0	164025.0	179309.0	122349.0	148390.0	199389.0	161091.0	301360.0	185947.0	179933.0	264136.0	199718.0	101379.0	122774.0	175151.0	134096.0	135701.0	255163.0	230285.0	215407.0	210443.0	151477.0	281763.0	245097.0	206120.0	368414.0	131708.0	240120.0	167611.0	191019.0	310267.0	122452.0	113771.0	89266.0	113642.0	83395.0	164352.0	166833.0	128903.0	150070.0	201889.0	153693.0	87099.0	146869.0	138483.0	145628.0	210441.0	205746.0	272758.0	242028.0	213728.0
Unclassified|Poorly Characterized|Function unknown	278767.0	319044.0	245013.0	216712.0	132751.0	258617.0	325000.0	345850.0	305455.0	263422.0	224644.0	244295.0	253178.0	298655.0	215351.0	199403.0	239955.0	259726.0	168211.0	229605.0	319858.0	221603.0	602835.0	272790.0	258408.0	375733.0	320923.0	148855.0	185601.0	260430.0	203181.0	212524.0	315299.0	288276.0	278544.0	290849.0	190622.0	548385.0	468356.0	390699.0	740154.0	214662.0	478002.0	347761.0	396836.0	653391.0	245480.0	204640.0	180853.0	195102.0	150826.0	243304.0	220191.0	184080.0	178924.0	281926.0	222922.0	127726.0	198502.0	198541.0	228945.0	349367.0	348293.0	437678.0	368426.0	309777.0
Unclassified|Poorly Characterized|General function prediction only	613216.0	692726.0	527435.0	481722.0	360580.0	499778.0	608837.0	683035.0	589193.0	497258.0	520411.0	568568.0	586298.0	699186.0	524725.0	466202.0	585477.0	644165.0	402099.0	534426.0	707261.0	567130.0	1038138.0	614698.0	600309.0	946053.0	701451.0	389297.0	474378.0	651932.0	487433.0	486225.0	834241.0	747250.0	708181.0	710782.0	555195.0	990836.0	869613.0	706281.0	1268108.0	454341.0	790473.0	567525.0	643763.0	1041154.0	441087.0	390720.0	322833.0	382795.0	289316.0	565533.0	539807.0	428828.0	486773.0	709535.0	524090.0	297972.0	486537.0	472337.0	533854.0	652033.0	637509.0	916318.0	760569.0	704027.0